Fabrication of hydroxyapatite from fish bones waste using reflux method

Cahyanto, Arief; Kosasih, Engkos Achmad; Aripin, Dudi; Hasratiningsih, Zulia

doi:10.1088/1757-899x/172/1/012006

Cited by 28 publications

(15 citation statements)

References 7 publications

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“…calcined at 900˚C is presented in Figure 2. In this image, the morphology of hydroxyapatite was found porous with pore size less than 1 μm in average and nonhomogeneous [8]. surface morphology of the prepared hydroxypatite (HAP) ceramic particles via calcinations of natural bones and synthetic sol-gel method and observed the aggregation of particles with rough and granular to dense surfaces.…”

Section: Properties Of Hydroxyapatitementioning

confidence: 80%

“…Hydroxyapatite has the capability to form chemical bonds with surrounding hard tissues [39] [40] with the formation of a HAP interfacial layer [41]. The similar physical and chemical characteristics of natural hydroxyapatite with bone make it biocompatible [8].…”

Section: Properties Of Hydroxyapatitementioning

confidence: 99%

“…It is a main component of bone mineral but in some cases carbonate-apatite is a main hard tissue component, as in dental enamel [4]. One of the most common apatites used as bioceramic in medicine and dentistry is hydroxyapatite (HAP) due to its bioactivity and osteoconductive properties in vivo [5] [6] [7] [8]. The advantage of using HAP as a bioceramic or biomaterial compared to other bioceramics, such as Bioglass or A-W glass-ceramic, is its chemical similarity to the inorganic component of bone and tooth.…”

Section: Introductionmentioning

confidence: 99%

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Hydroxyapatite: Preparation, Properties and Its Biomedical Applications

Pokhrel¹

2018

ACES

100

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Hydroxyapatite, a naturally occurring form of calcium phosphate, is the main mineral component of bones and teeth. Natural hydroxyapatite and bone have similar physical and chemical characteristics make it biocompatible. Its porous structure resembles native bone. The biocompatibility, biodegradability and bioactivity make it extensively useful in interdisciplinary fields of sciences like chemistry, biology, and medicine. Calcium phosphate-based ceramics are of great interest as substitutes of synthetic bone graft due to their similarities in composition to bone mineral and bioactivity as well as osteoconductivity. This article gives an overview of hydroxyapatite from its preparation and properties to biomedical applications of its composites.

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Section: Properties Of Hydroxyapatitementioning

confidence: 80%

Section: Properties Of Hydroxyapatitementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Hydroxyapatite: Preparation, Properties and Its Biomedical Applications

Pokhrel¹

2018

ACES

100

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“…Researchers have synthesised hydroxyapatite using different techniques, such as hydrothermal synthesis, precipitation, and hydrolysis, as well as employing natural resources, like bovine bones [ 37 , 38 , 39 , 40 ], fish bones [ 41 , 42 , 43 ], marine shells [ 44 , 45 , 46 ], and eggshells [ 45 , 47 , 48 , 49 ]). Historically, the usage of xenogeneic bone, like Kiel bone (actual bone harvested from calf or ox) and Boplant (actual bone harvested from a calf) in biomedical applications, were thought to be the alternate to auto- or homografts, mainly due to limited supply of grafts, site morbidity, and the difficulty/expense of multiple surgical processes [ 22 ].…”

Section: Hydroxyapatitementioning

confidence: 99%

A Review on the Use of Hydroxyapatite-Carbonaceous Structure Composites in Bone Replacement Materials for Strengthening Purposes

2018

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Biomedical materials constitute a vast scientific research field, which is devoted to producing medical devices which aid in enhancing human life. In this field, there is an enormous demand for long-lasting implants and bone substitutes that avoid rejection issues whilst providing favourable bioactivity, osteoconductivity and robust mechanical properties. Hydroxyapatite (HAp)-based biomaterials possess a close chemical resemblance to the mineral phase of bone, which give rise to their excellent biocompatibility, so allowing for them to serve the purpose of a bone-substituting and osteoconductive scaffold. The biodegradability of HAp is low (Ksp ≈ 6.62 × 10−126) as compared to other calcium phosphates materials, however they are known for their ability to develop bone-like apatite coatings on their surface for enhanced bone bonding. Despite its favourable bone regeneration properties, restrictions on the use of pure HAp ceramics in high load-bearing applications exist due to its inherently low mechanical properties (including low strength and fracture toughness, and poor wear resistance). Recent innovations in the field of bio-composites and nanoscience have reignited the investigation of utilising different carbonaceous materials for enhancing the mechanical properties of composites, including HAp-based bio-composites. Researchers have preferred carbonaceous materials with hydroxyapatite due to their inherent biocompatibility and good structural properties. It has been demonstrated that different structures of carbonaceous material can be used to improve the fracture toughness of HAp, as they can easily serve the purpose of being a second phase reinforcement, with the resulting composite still being a biocompatible material. Nanostructured carbonaceous structures, especially those in the form of fibres and sheets, were found to be very effective in increasing the fracture toughness values of HAp. Minor addition of CNTs (3 wt.%) has resulted in a more than 200% increase in fracture toughness of hydroxyapatite-nanorods/CNTs made using spark plasma sintering. This paper presents a current review of the research field of using different carbonaceous materials composited with hydroxyapatite with the intent being to produce high performance biomedically targeted materials.

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“…Several research has been conducted to increase the economic value of fish bone waste, for example fish bone flour [3,4], gelatin [2], and hydroxyapatite production [5][6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Preparation and Characterization Nanoparticle Calcium Oxide from Snakehead Fish Bone using Ball Milling Method

Muryati

Hariani

Said

2019

IJFAC

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Snakehead Fish Bone (SFB) is a waste from food processing in Palembang. Fish bones have calcium content so they have a potential as a source of Calcium Oxide (CaO). Calcination of fish bones was carried out at a temperature of 900 o C with variations of time 1, 2, 3, and 4 hours. The Nanoparticle Calcium Oxide (NCO) was prepared using the ball milling method. This study aims to make NCO as a raw material for hydroxyapatite synthesis. The NCO was characterized using Fourier Transform Infra-Red (FTIR), X-Ray Diffraction (XRD), and Scanning Electron Microscope (SEM). Characterization using FTIR shows that NCO has functional groups O-H, CO 3 2and PO 4 3functional groups. XRD analysis shows that NCO has an average particle size of 38.9445 nm. Analysis using SEM shows particles in the form of granules of almost uniform size. The NCO produced eligible of the nanomaterial and has the potential as a raw material for synthesis of hydroxyapatite.

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Fabrication of hydroxyapatite from fish bones waste using reflux method

Cited by 28 publications

References 7 publications

Hydroxyapatite: Preparation, Properties and Its Biomedical Applications

Hydroxyapatite: Preparation, Properties and Its Biomedical Applications

A Review on the Use of Hydroxyapatite-Carbonaceous Structure Composites in Bone Replacement Materials for Strengthening Purposes

Preparation and Characterization Nanoparticle Calcium Oxide from Snakehead Fish Bone using Ball Milling Method

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