Facile fabrication of core cross-linked micelles by RAFT polymerization and enzyme-mediated reaction

Wu, Yukun; Lai, Quanyong; Lai, S. L.; Wu, Jieying; Wang, Wei; Yuan, Zhi

doi:10.1016/j.colsurfb.2014.03.031

Cited by 16 publications

(9 citation statements)

References 56 publications

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“…These micelles showed better anticancer activity than free DOX. Yukun Wu et al 253 tested a method to increase the stability of an amphiphilic block copolymer by developing novel core cross-linked micelles. They synthesized poly(ethylene glycol)- block -poly( N -isopropylacrylamide- co -N-(4-hydroxypHenethyl) acrylamide) diblock copolymer (PEG- b -P(NIPAAm- co -NHPAAm)).…”

Section: Dual Stimuli In Temperature-responsive Systemsmentioning

confidence: 99%

Temperature-Responsive Smart Nanocarriers for Delivery Of Therapeutic Agents: Applications and Recent Advances

Karimi

Zangabad

Ghasemi

et al. 2016

ACS Appl. Mater. Interfaces

359

212

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Smart drug delivery systems (DDSs) have attracted the attention of many scientists, as carriers that can be stimulated by changes in environmental parameters such as temperature, pH, light, electromagnetic fields, mechanical forces, etc. These smart nanocarriers can release their cargo on demand when their target is reached and the stimulus is applied. Using the techniques of nanotechnology, these nanocarriers can be tailored to be target-specific, and exhibit delayed or controlled release of drugs. Temperature-responsive nanocarriers are one of most important groups of smart nanoparticles (NPs) that have been investigated during the past decades. Temperature can either act as an external stimulus when heat is applied from the outside, or can be internal when pathological lesions have a naturally elevated termperature. A low critical solution temperature (LCST) is a special feature of some polymeric materials, and most of the temperature-responsive nanocarriers have been designed based on this feature. In this review, we attempt to summarize recent efforts to prepare innovative temperature-responsive nanocarriers and discuss their novel applications.

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Section: Dual Stimuli In Temperature-responsive Systemsmentioning

confidence: 99%

Temperature-Responsive Smart Nanocarriers for Delivery Of Therapeutic Agents: Applications and Recent Advances

Karimi

Zangabad

Ghasemi

et al. 2016

ACS Appl. Mater. Interfaces

359

212

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“…Various approaches to fabricate self-healing microcapsules have been widely reported, including layer-by-layer assembly techniques, 19,20 self-assembly of amphiphilic block copolymers into spherically closed structures by reversible addition fragmentation chain transfer (RAFT) polymerization, 21 solvent evaporation method, 22 coacervation, 23 and microuidic techniques. [24][25][26][27] Nevertheless, when the wrapped core material is liquid isophorone diisocyanate (IPDI), capsulation technology is severely restricted because IPDI is a highly reactive healing reagent for a one-component catalyst-free self-healing system.…”

Section: Introductionmentioning

confidence: 99%

Multilayer composite microcapsules synthesized by Pickering emulsion templates and their application in self-healing coating

Yang

et al. 2015

J. Mater. Chem. A

161

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ARTICLE This journal isMultilayer composite microcapsules, richly and efficiently loaded with healing reagents (Isophorone diisocyanate, IPDI), are prepared based on lignin nanoparticle-stabilized oil-in-water (O/W) Pickering emulsion templates. The size control of the microcapsules is conducted by varying the lignin content and oil-water volume ratio in Pickering emulsions. With scanning electron microscope (SEM) and optical microscope (OM), the resulting microcapsules show spherical shape, ideal structure of rough outer surface and smooth inner surface, shell thickness of 4.5 m and mean diameter of 40-117 m. Fourier transform infrared spectra (FTIR) and Thermal gravimetric analysis (TGA) indicate extraordinary characteristics of the capsules: core fractions of 81.1 wt.%, excellent thermal stability with initial evaporating temperature of IPDI elevated for 72 °C, firm durability among aqueous solution-submersion and air-exposure with mass loss about 9.7 wt.% after four days submersion or two weeks exposure. Furthermore, the microcapsules are embedded into epoxy coatings for applying this technology into anticorrosive polymer coatings. Investigated by brine-submersion corrosion-accelerating test, the selfhealing microcapsules-incorporated epoxy coatings on steel plates demonstrate good dispersibility of capsules in coatings and favourable anticorrosive effects.

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“…Another very important approach is enzyme-responsive cross-linking or breaking of cross-links that is given in Figure 10e. Crosslinked micelles and gels can be obtained using this approach as well [387,388].…”

Section: Biochemical Stimuli-responsive Polymersmentioning

confidence: 99%

Stimuli-Responsive Polymers Providing New Opportunities for Various Applications

Koçak

Tuncer

Bütün

2020

Hacettepe Journal of Biology and Chemistry

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U yaranlara duyarlı polimerler, çevrelerindeki koşullarda küçük bir değişiklik olduğunda fiziksel veya kimyasal özelliklerini önemli ölçüde değiştirir. Koşullardaki değişikliklere bağlı olarak, bu tür kopolimerler kendiliğinden bir araya gelebilir ve çeşitli nanoboyutlu yapılar oluşturabilir. Bu tür polimerlerin farklı alanlarda önemli kullanımları vardır. Bu derlemede, çevreye duyarlı farklı polimerlerin mimarileri, duyarlılıklarına göre sınıflandırmaları ve çeşitli alanlardaki uygulamaları gibi temel konulardaki bazı güncel literatür raporlarının bir analizini sunuyoruz. Son yirmi yılda, biyoteknoloji, nanoteknoloji, kolloid ve yüzey bilimi, malzeme bilimi vb. dahil olmak üzere çeşitli uygulamalar için uygun uyarıcıya duyarlı yeni polimerlerin ve polimerik malzemelerin hazırlanmasına yönelik sentetik yöntemlerde ve stratejilerde büyük gelişmeler olmuştur. Çok geniş kapsamı olan bu polimer türünün okuyucular tarafından daha anlaşılır olabilmesi için genellikle temel kavramlar/konular şematize edilmiştir. Ayrıca, bu malzemelerin üretiminde izlenebilecek stratejiler yeter düzeyde verilmeye çalışılmıştır. Anahtar KelimelerUyarıya-duyarlı polimerler, kendi-kendine-düzenlenme, nanoyapılar, akıllı polimerler.

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Facile fabrication of core cross-linked micelles by RAFT polymerization and enzyme-mediated reaction

Cited by 16 publications

References 56 publications

Temperature-Responsive Smart Nanocarriers for Delivery Of Therapeutic Agents: Applications and Recent Advances

Temperature-Responsive Smart Nanocarriers for Delivery Of Therapeutic Agents: Applications and Recent Advances

Multilayer composite microcapsules synthesized by Pickering emulsion templates and their application in self-healing coating

Stimuli-Responsive Polymers Providing New Opportunities for Various Applications

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