Facile synthesis of simple mono-alkyl phosphates from phosphoric acid and alcohols

Biosynthesis of a water-soluble lipid I analogue and a convenient assay for translocase I

“…Lyophilization of the aqueous phase gave the crude product. Purification by DOWEX 50WX8 afforded neryl phosphate ( 6 )-mono ammounium salt (0.17g, 74%) as a white solid [29]. This reaction could readily be scaled up to multi grams of neryl phosphate-mono ammonium salt.…”

A novel synthetic approach to glycerophospholipids via Horner–Wadsworth–Emmons reaction of mixed phosphonoacetate

“…[8][9][10][11] Chemical synthesis of natural and unnatural glycerophospholipids has recently attracted much attention because of their variety of biological activities. [12][13][14][15][16][17][18][19][20][21][22] In some cases, however, the amphipathic property of glycerophospholipids, which is attributed to their hydrophilic region (a phosphorylated alcohol moiety) and hydrophobic region (a diacylglycerol moiety), causes difficulties in the handling of these compounds and their precursors during their organic synthesis.…”

Synthesis of acid–base bifunctional CaO/ITQ-2 zeolite catalyst for phosphorylation of dodecanol

“…Phosphate esters of long-chain alkyl alcohols are widely used as antistatic agents, emulsifiers, wetting agents, hydrotropes and intermediates in medical chemistry [1][2][3][4]. Di-dodecyl phosphate ester (DAP) is an important intermediate of pesticides and textile smoothing agents.…”