Factors associated with global cognitive impairment in epilepsy patients: a cross-sectional study in Mataram, Indonesia

Harahap, Herpan Syafii; Rizki, Mohammad; Irawati, Deasy

doi:10.13181/mji.oa.226118

Cited by 2 publications

(2 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Educational level is another factor that affects the occurrence of cognitive impairment among epileptic patients; studies identified cognitive impairment is inversely associated with education level (Beh et al, 2020; Harahap et al, 2022; Wang et al, 2019).…”

Section: Literature Reviewmentioning

confidence: 99%

Magnitude of Cognitive Impairment Among Patients With Epilepsy at Health Institutions in Gurage Zone, Ethiopia

et al. 2023

View full text Add to dashboard Cite

Introduction Epilepsy is a widespread neurological disorder characterized by recurrent unprovoked seizures; it contributes to 1% of the global burden of diseases and can end in cognitive impairment. Objective To assess the magnitude and associated factors of cognitive impairment among patients with epilepsy. Method The study utilized an institution-based cross-sectional study design. All patients with epilepsy whose ages were above 18 years were the source population. The authors performed bivariate and multivariate logistic regression analyses. Finally, variables with a p-value <.05 were significantly associated. Result The magnitude of cognitive impairment is 25.6%. Having no family history of epilepsy (AOR=0.12; 95% CI [0.02, 0.61]), polytherapy (AOR=5.14; 95% CI [1.12, 23.62]), and medication-related complaints (AOR=8.24; 95% CI [1.87, 36.38]) were strongly associated with cognitive impairment. Conclusion Significant numbers of patients were positive for cognitive impairment. Family history, polytherapy, and medication-related complaints were associated factors.

show abstract

Section: Literature Reviewmentioning

confidence: 99%

Magnitude of Cognitive Impairment Among Patients With Epilepsy at Health Institutions in Gurage Zone, Ethiopia

et al. 2023

View full text Add to dashboard Cite

show abstract

“…This evaluation aims to guide diagnostic ceonsiderations, treatment initiation, and administration of anti-seizure medications to reduce the life-threatening effects of prolonged seizures and status epilepticus, 3 as well as global cognitive impairment. 4 The first seizure episode is a life-changing event with psychophysical consequences. 5 Patients must be appropriately assessed and managed immediately after an unprovoked seizure.…”

mentioning

confidence: 99%

Risk of seizure recurrence in children with new-onset afebrile seizure

Taha,

Muhammed

2023

Med J Indones

View full text Add to dashboard Cite

BACKGROUND A seizure is a brief change in the normal neuronal electrical activity of the brain that causes changes in consciousness, perception, behavior, or movement. This study aimed to evaluate clinical findings, initial electroencephalography (EEG), and brain imaging findings as predictors of seizure recurrence after the first nonfebrile seizure. METHODS This prospective follow-up study was conducted at Azadi Teaching Hospital, Kirkuk from July 2019 to January 2022 and enrolled 150 patients, ranging from 1 month to 15 years of age, who presented with their first afebrile seizure. The seizure types were classified based on the International League Against Epilepsy in 2017. A brain imaging with EEG was performed within 72 hours after admission. RESULTS The median age of the patients was 5 years. A higher risk of seizure recurrence occurred in patients with focal seizure (relative risk [RR] = 6.604) (95% confidence interval [CI] 3.975–10.971), seizure occurrence at sleep (RR = 3.815) (95% CI 2.410–6.039), an abnormal neurological presentation such as Todd’s paralysis (RR = 1.739) (95% CI 1.252–2.415), a positive family history of seizures (RR = 2.333) (95% CI 1.598–3.408), abnormal EEG (RR = 0.171) (95% CI 0.092–0.318), and abnormal brain image findings (RR = 0.681) (95% CI 0.492–0.941) within 72 hours. Seizure recurrence was not correlated with sex. CONCLUSIONS Early and late childhood new-onset afebrile seizures with a positive family history, focal epilepsy, seizure during sleep, prolonged attack duration with frequent attacks within 24 hours, and abnormal initial EEG and brain image had a high risk of seizure recurrence.

show abstract

Factors associated with global cognitive impairment in epilepsy patients: a cross-sectional study in Mataram, Indonesia

Cited by 2 publications

References 24 publications

Magnitude of Cognitive Impairment Among Patients With Epilepsy at Health Institutions in Gurage Zone, Ethiopia

Magnitude of Cognitive Impairment Among Patients With Epilepsy at Health Institutions in Gurage Zone, Ethiopia

Risk of seizure recurrence in children with new-onset afebrile seizure

Contact Info

Product

Resources

About