Factors promoting the tissue dissolving capability of sodium hypochlorite

Abstract

EA 157, Metrohm, Herisau, Switzerland.

Endodontic Irrigation Solutions: A Review

“…The disinfecting properties of hypochlorite solutions decrease with increasing pH, whereas their antimicrobial efficacy increases with decreasing pH. 15 Moorer and Wesselink found that mechanical agitation with NaOCl is very important for the generation of a tissue-dissolving effect (9). Ultrasonic agitation increased the activity of a 5% NaOCl solution in the apical third of the root canal wall (16).…”

“…High concentrations of NaOCl have better tissue-dissolving effects. Low concentrations used in high volumes have potency equivalent to that of high concentrations (9). In addition, higher concentrations of NaOCl are more toxic than lower concentrations (10).…”

Eradication of Intracanal Enterococcus Faecalis Biofilm by Passive Ultrasonic Irrigation and RinsEndo System

“…Therefore, it may be suggested that there may be a point of saturation and the increase in volume beyond which bacterial elimination in the complex root canal space will no longer improve (28). In addition, Moorer and Wesselink (30) found that chlorine, which is responsible for the antimicrobial effect of NaOCl, is consumed rapidly within 2 min, so the time of 45 s is probably too short for the effective antimicrobial efficacy of 3% NaOCl against 21 days old E. faeaclis colonization.…”

Avaliação histológica da limpeza dos canais radiculares promovida por diferentes métodos de irrigação e análise tomográfica da área apical no comprimento de trabalho

“…Esta última promovendo além do arrasto de irritantes; restos de sangue; detritos e raspas de dentina, tanto da câmara pulpar quanto dos canalículos dentinários. (FIGDOR; SUNDQVIST, 2007;HAAPASSALO et al 2005;LOPES & SIQUEIRA JR, 2004;MOORER;WESSELINK, 1982).…”

“…Outros fatores relacionados à irrigação podem influenciar na eficácia da solução tais como: volume; profundidade de penetração da agulha de irrigação; tempo de permanência da solução no interior do canal radicular; área de contato e, aquecimento da solução, que no caso do hipoclorito de sódio, potencializa a dissolução de tecido orgânico (ALBRECHT; ESTRELA et al, 2002;GAMBARINI, 1999;MOORER;WESSELINK, 1982;WALTERS et al, 2002).…”