First and foremost, I would like to thank my supervisor, Prof. Alex C. Kot, for giving me the opportunity to pursuit the Ph.D. in such a renowned institution as NTU, and for providing me important guidance throughout this journey. I am also grateful to Prof. Anderson Rocha for enabling this opportunity by recommending me to Prof. Kot, and also for his support in the early stages of my doctorate studies.I wish to thank all of those that I have met during my time in ROSE lab, including the Ph.D. colleagues, interns and staff. In special, I want to express my deepest gratitude to Abrar, Kamila, Raman, and Yasin, for their warm welcoming and companionship during my studies. I am thankful as well to Jun, for working together with me in essential projects carried out during my Ph.D. research. I feel extremely grateful for all of the amazing people I have encountered around NTU and Singapore, which I had the chance to create deep and meaningful connections with. Their support throughout this period, by sharing so many joyful moments and lending me an ear when necessary, was invaluable for me to endure my studies. They are also responsible for many happy memories, that I will carry out with me for the rest of my life.At last, I would like to thank those that have supported me from so far away.I have a profound gratitude to my dear friends, in Brazil or spread across the globe. Their loyal friendship, despite the long distance, was paramount to give me strength to accomplish this thesis. I am also deeply grateful to my family, for being so understanding with me living geographically so distant during this period. Overcoming the physical barrier, their loving feelings sent through messages, pictures and videos, always warmed my heart and gave me peace of mind to carry on.ix "As a well spent day brings happy sleep, so a life well spent brings happy death."
-da Vinci, LeonardoTo my loving dog Bazinga, forever in my happiest memories