Feature-space assessment of electrical impedance tomography coregistered with computed tomography in detecting multiple contrast targets

Krishnan, K. Gopala; Liu, Jeff; Kohli, Kirpal

doi:10.1118/1.4873326

Cited by 8 publications

(3 citation statements)

References 31 publications

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“…The feasibility of reduced-order models using orthogonal decomposition of conductivity and potential distributions has been demonstrated in simulations and tank measurements 47 , but no individual structural information is embedded in the reconstruction. An approach that shows the capabilities of image fusion of CT and EIT data utilizing a coregistration algorithm is described for measurements on a phantom 54 . However, neither structural information is directly used in the EIT reconstruction nor is the dimensionality of the problem reduced.…”

Section: Discussionmentioning

confidence: 99%

Structural-functional lung imaging using a combined CT-EIT and a Discrete Cosine Transformation reconstruction method

Schullcke

Gong

Krueger-Ziolek

et al. 2016

Sci Rep

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Lung EIT is a functional imaging method that utilizes electrical currents to reconstruct images of conductivity changes inside the thorax. This technique is radiation free and applicable at the bedside, but lacks of spatial resolution compared to morphological imaging methods such as X-ray computed tomography (CT). In this article we describe an approach for EIT image reconstruction using morphologic information obtained from other structural imaging modalities. This leads to recon- structed images of lung ventilation that can easily be superimposed with structural CT or MRI images, which facilitates image interpretation. The approach is based on a Discrete Cosine Transformation (DCT) of an image of the considered transversal thorax slice. The use of DCT enables reduction of the dimensionality of the reconstruction and ensures that only conductivity changes of the lungs are reconstructed and displayed. The DCT based approach is well suited to fuse morphological image information with functional lung imaging at low computational costs. Results on simulated data indicate that this approach preserves the morphological structures of the lungs and avoids blurring of the solution. Images from patient measurements reveal the capabilities of the method and demonstrate benefits in possible applications.

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Section: Discussionmentioning

confidence: 99%

Structural-functional lung imaging using a combined CT-EIT and a Discrete Cosine Transformation reconstruction method

Schullcke

Gong

Krueger-Ziolek

et al. 2016

Sci Rep

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“…The premenstrual syndrome can be determined from the intracellular versus extracellular fluid [5]. The workflow of EIT system is a combination of frequency generator, phase shifter, multiplier, demodulator, and signal conditioner that are connected with objects via multiplexers and several electrodes [6]. The simplified structure of the EIT system is shown in figure 1.…”

Section: Introductionmentioning

confidence: 99%

Survey on Medical Imaging of Electrical Impedance Tomography (EIT) by Variable Current Pattern Methods

Adam¹,

Sathesh²

2021

JISMAC

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Recently, the image reconstruction study on EIT plays a vital role in the medical application field for validation and calibration purpose. This research article analyzes the different types of reconstruction algorithms of EIT in medical imaging applications. Besides, it reviews many methods involved in constructing the electrical impedance tomography. The spatial distribution and resolution with different sensitivity has been discussed here. The electrode arrangement of various methods involved in the EIT system is discussed here. This research article comprises of adjacent drive method, cross method, and alternative opposite current direction method based on the voltage driven pattern. The assessment process of biomedical EIT has been discussed and investigated through the impedance imaging of the existent substances. The locality of the electrodes can be calculated and fixed for appropriate methods. More specifically, this research article discusses about the EIT image reconstruction methods and the significance of the alternative opposite current direction approach in the biomedical system. The change in conductivity test is further investigated based on the injection of current flow in the system. It has been established by the use of Electrical Impedance Tomography and Diffuse Optical Tomography Reconstruction Software (EDITORS) software, which is open-source software.

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“…Compared with conventional external radiotherapy, interstitial brachytherapy features fewer complications, less trauma, safety, and efficacy. It further improves the anti-tumor effect via killing tumor cells and most effectively protects normal tissue [11,12], and therefore has been rapidly applied in clinic. At present, the preferred choice of therapy in early prostate cancer therapy is interstitial implant with 125 I particle.…”

Section: Introductionmentioning

confidence: 99%

The Mechanism of Computed Tomography-Guided 125I Particle in Treating Lung Cancer

Jin

Yang

et al. 2017

Med Sci Monit

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BackgroundThe incidence of malignant tumor has gradually increased. How to improve the survival and quality of life of patients who lose the opportunity for surgery or who are unwilling to receive surgery remains an obstacle. At present, 125I particle interstitial implant therapy has been applied in a variety of treatments of tumors. However, the mechanism of computed tomography (CT)-guided 125I particle therapy in lung cancer has not been fully elucidated.Material/MethodsA total of 42 patients with advanced non-small cell lung cancer were retrospectively analyzed between January 2013 and December 2013, including 19 patients who received CT-guided 125I particle therapy and 23 patients who received chemotherapy. Curative effect and adverse reactions at 6 months and 12 months were compared and analyzed. A rabbit lung cancer VX2 model was treated by 125I particle implantation therapy under CT guidance. The change in tumor volume was detected. Tumor cell apoptosis was tested by flow cytometry. Bcl-2 and Bax expression were determined by real-time polymerase chain reaction (PCR) and Western blot.Results125I particle therapy obviously reduced tumor volume after 6 months and 12 months. It showed significantly higher efficiency (57.9%, 57.9%) and control (78.9%, 73.7%) than the rates of efficiency and control in the chemotherapy group (P<0.05). 125I particle implantation therapy markedly suppressed rabbit VX2 transplanted tumor cell proliferation, promoted tumor regression, induced tumor cell apoptosis, reduced Bcl-2 expression, and upregulated Bax expression level (P<0.05).ConclusionsCT-guided 125I particle implantation therapy can inhibit tumor proliferation and growth by regulating the expression of apoptosis-related genes and proteins, which is a promising approach in lung cancer treatment.

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Feature-space assessment of electrical impedance tomography coregistered with computed tomography in detecting multiple contrast targets

Cited by 8 publications

References 31 publications

Structural-functional lung imaging using a combined CT-EIT and a Discrete Cosine Transformation reconstruction method

Structural-functional lung imaging using a combined CT-EIT and a Discrete Cosine Transformation reconstruction method

Survey on Medical Imaging of Electrical Impedance Tomography (EIT) by Variable Current Pattern Methods

The Mechanism of Computed Tomography-Guided 125I Particle in Treating Lung Cancer

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