Features of Kidney Function in Patients With Comorbidity of Arterial Hypertension and Chronic Obstructive Pulmonary Disease

Boiko, Olha; Родіонова, В. В.; Shevchenko, Luydmyla

doi:10.7759/cureus.31828

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…В многочисленных исследованиях доказана ассоциация хронической обструктивной болезни легких (ХОБЛ) и почечной дисфункции [7; 8]. Наряду с этим работы, посвященные изучению функции почек при сочетании ИМ и ХОБЛ, единичны [9]. В связи с этим представляется обоснованным определение функции органов выделения (креатинин, СКФ) у больных инфарктом миокарда в сочетании с ХОБЛ.…”

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Renal Function in Myocardial Infarction in Patients With Chronic Obstructive Pulmonary Disease

Прокофьева¹,

Polunina²,

Belyakova³

2023

СПНО (MPSE)

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Инфаркт миокарда (ИМ) продолжает лидировать среди причин смертности населения экономически развитых стран мира. Особенно опасно сочетание ИМ с другими хроническими заболеваниями, например с хронической обструктивной болезнью легких (ХОБЛ). Нарушение работы почек у больных с острым коронарным синдромом и ИМ встречается нередко и сопряжено с неблагоприятным прогнозом. Работы по оценке почечной функции у больных с сочетанием ИМ и ХОБЛ единичны. Целью исследования явилось: определить наличие почечной дисфункции в остром периоде инфаркта миокарда у больных с хронической обструктивной болезнью легких. Обследовано 195 больных ИМ+ХОБЛ, 130 больных ИМ без ХОБЛ и 110 соматически здоровых лиц. Оцениваемыми параметрами были: уровни мочевины, креатинина, скорость клубочковой фильтрации (СКФ), наличие протеинурии. Статобработка полученных данных осуществлялась с помощью программы SPSS 26.0. В обеих группах больных ИМ (ИМ+ХОБЛ и ИМ без ХОБЛ) уровни мочевины, креатинина и СКФ превосходили значения, полученные в группе контроля. При сравнении показателей внутри групп статистически значимые различия получены только для СКФ -у больных ИМ+ХОБЛ СКФ была наименьшей. Уровни мочевины и креатинина в группах наблюдения были сопоставимы. Удельный вес больных с протеинурией был наибольшим в группе больных ИМ без ХОБЛ. Не наблюдалось зависимости значений показателей от наличия зубца Q на ЭКГ. Ключевые слова: коморбидность, инфаркт миокарда, хроническая обструктивная болезнь легких, почечная дисфункция.

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“…(2022). При сравнении трех групп -с ХОБЛ, сердечно-сосудистой патологией и коморбидных пациентов -наиболее выраженное снижение СКФ определялось также среди лиц с коморбидной патологией[9].Заключение.…”

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Renal Function in Myocardial Infarction in Patients With Chronic Obstructive Pulmonary Disease

Прокофьева¹,

Polunina²,

Belyakova³

2023

СПНО (MPSE)

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The Relationship between The Characteristics of Type 2 Diabetes Mellitus Patients and The Chronic Kidney Disease Stage during The COVID-19 Pandemic at RSI Jemursari Surabaya

Irawan,

Effendi,

Donastin

et al. 2024

IIMJ

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Introduction: The prevalence of diabetes mellitus has risen globally, posing a substantial health challenge, with a marked increase reported in both developed and developing nations. Diabetes is a primary contributor to the global prevalence of Chronic Kidney Disease (CKD). During the pandemic, there is a considerable challenge, especially for CKD patients, including a loss in health services, vulnerability to COVID-19 infection, stressful events during social distancing, and a decrease in therapy adherence. Hence, the COVID-19 pandemic may give rise to various characteristics in individuals with chronic kidney disease. Objective: To investigate the correlation between the characteristic of patients with type 2 diabetes mellitus and the chronic kidney disease (CKD) stage at RSI Jemursari Surabaya during the COVID-19 pandemic. Methods: An observational analytical cross-sectional study was conducted on individuals with chronic kidney disease (CKD) previously diagnosed with diabetes mellitus (DM) during the COVID-19 pandemic from 2020 to 2022. A total of 169 samples were obtained using a simple random sampling method. The variables considered include age, gender, HbA1c, blood pressure, cardiovascular comorbidities, Pulmonary comorbidities, and history of COVID-19. Results: The study demonstrated a significant correlation between blood pressure and kidney function tests, including blood creatine level, BUN, and eGFR, with CKD stage (P<0.05). Randomised blood glucose also has a significant correlation to the CKD stage. No notable correlation was observed among age, gender, HbA1c levels, cardiovascular comorbidities, pulmonary comorbidities, and history of COVID-19. Conclusions: The presence of hypertension and abnormal kidney function test results correlate with the stage of chronic kidney disease (CKD) during a pandemic.

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Lung Dysfunction and Chronic Kidney Disease: A Complex Network of Multiple Interactions

Gembillo

Calimeri

Tranchida

et al. 2023

JPM

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Chronic kidney disease (CKD) is a progressive disease that affects > 10% of the total population worldwide or >800 million people. CKD poses a particularly heavy burden in low- and middle-income countries, which are least able to cope with its consequences. It has become one of the leading causes of death worldwide and is one of the few non-communicable diseases where the number of related deaths has increased over the last two decades. The high number of people affected, and the significant negative impact of CKD should be a reason to increase efforts to improve prevention and treatment. The interaction of lung and kidney leads to highly complex and difficult clinical scenarios. CKD significantly affects the physiology of the lung by altering fluid homeostasis, acid-base balance and vascular tone. In the lung, haemodynamic disturbances lead to the development of alterations in ventilatory control, pulmonary congestion, capillary stress failure and pulmonary vascular disease. In the kidney, haemodynamic disturbances lead to sodium and water retention and the deterioration of renal function. In this article, we would like to draw attention to the importance of harmonising the definitions of clinical events in pneumology and renal medicine. We would also like to highlight the need for pulmonary function tests in routine clinical practise for the management of patients with CKD, in order to find new concepts for pathophysiological based disease-specific management strategies.

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Features of Kidney Function in Patients With Comorbidity of Arterial Hypertension and Chronic Obstructive Pulmonary Disease

Cited by 3 publications

References 19 publications

Renal Function in Myocardial Infarction in Patients With Chronic Obstructive Pulmonary Disease

Renal Function in Myocardial Infarction in Patients With Chronic Obstructive Pulmonary Disease

The Relationship between The Characteristics of Type 2 Diabetes Mellitus Patients and The Chronic Kidney Disease Stage during The COVID-19 Pandemic at RSI Jemursari Surabaya

Lung Dysfunction and Chronic Kidney Disease: A Complex Network of Multiple Interactions

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