Fetal MRI of CNS abnormalities

Masselli, Gabriele; Notte, M. R. Vaccaro; Zacharzewska-Gondek, A.; Laghi, Francesca; Manganaro, Lucia; Brunelli, Roberto

doi:10.1016/j.crad.2020.03.035

Cited by 26 publications

(14 citation statements)

References 9 publications

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“…The high signal in the cerebrospinal fluid gap around the brain, and the low signal in the lumen of the intracranial vessels (due to the "flow-through" effect in the SS-FSE sequence) formed an appropriate contrast, and the high resolution of this sequence facilitated the visualization of the fetal straight sinus. These findings were consistent with research conducted by Masselli et al (10).…”

Section: Discussionsupporting

confidence: 94%

“…In existing studies, the FIRM sequence was more commonly used to diagnose fetal cerebral hemorrhage (11). Although DWI sequences had significant advantages in investigations evaluating fetal brain development (10), this sequence was observed to have had some amplification effect on the fetal straight sinus in the present study. Therefore, the SS-FSE sequences may be more suitable than others for observing and evaluating the fetal straight sinus.…”

Section: Discussionmentioning

confidence: 60%

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Quantitative Evaluation of a Cross-Sectional Area of the Fetal Straight Sinus by Magnetic Resonance Imaging and Its Clinical Value

Xu²,

Liu³

et al. 2022

Front. Neurol.

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ObjectiveThe intracranial venous system plays an important role in ensuring blood circulation and a stable blood supply to the fetal brain. In the present study, a cross-sectional area of the fetal straight sinus was quantitatively evaluated by fetal magnetic resonance imaging (MRI) to explore the method's clinical value.MethodsThe clinical and MRI data of 126 normal fetuses in mid-to-late stage pregnancies were retrospectively analyzed. The “dominant” sequence of the fetal straight sinus was selected, and the cross-sectional area of the lumen was measured at each gestational age to obtain the normal range at different ages and to analyze the developmental pattern and characteristics of the fetal straight sinus.ResultsThere were statistically significant differences in the cross-sectional area of the fetal straight sinus among different gestational ages (P < 0.05). The cross-sectional area of the fetal straight sinus was positively correlated with gestational age (coefficient of determination = 0.6892, P < 0.05). That is, the cross-sectional area of the fetal straight sinus grew with increasing gestational age, and the regression equation was y = 0.27 x – 2.14 (P < 0.05). Additionally, there were five fetuses with cerebral venous abnormalities, including four with heart failure and one with venous sinus thrombosis.ConclusionQuantitative measurement of a cross-sectional area of the fetal straight sinus by MRI enhanced understanding of the anatomical features and developmental pattern of fetal cerebral veins and provided a reference for the clinical diagnosis of related diseases and investigation concerning pathogenesis.

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Section: Discussionsupporting

confidence: 94%

Section: Discussionmentioning

confidence: 60%

Quantitative Evaluation of a Cross-Sectional Area of the Fetal Straight Sinus by Magnetic Resonance Imaging and Its Clinical Value

Xu²,

Liu³

et al. 2022

Front. Neurol.

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“…The lumbar multifidus muscle plays a key role in maintaining spinal stability, and its functional status is closely related to low back pain. Magnetic resonance imaging (MRI) is an important clinical imaging tool, which can clearly display the morphological changes of the psoas major, multifidus muscle, and lumbar disc in patients with LDH and measure the cross-sectional area of BPMM and multifidus muscle, to provide reference for clinical diagnosis and treatment [ 11 , 12 ]. However, at the current stage, the value of MRI parameters in evaluating the therapeutic effect of PTED for patients with LDH is still under exploration.…”

Section: Introductionmentioning

confidence: 99%

Value of Lumbar MRI Parameters in the Evaluation of Postoperative Curative Effect on Patients with Lumbar Disc Herniation and Analysis of Risk Factors

Chen

2021

Evidence-Based Complementary and Alternative Medicine

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Objective. For exploring the value of magnetic resonance imaging (MRI) parameters in the evaluation of postoperative curative effect on patients with lumbar disc herniation (LDH) and analyzing risk factors. Methods. Totally 60 patients confirmed with LDH in our hospital between Jan. 2018 and Jan. 2020 were enrolled into the observation group (Obs group) given transforaminal endoscopic discectomy (TED). In addition, 60 individuals with low back pain but no LDH over the same time span were enrolled into the control group (Con group). The two groups were given lumbar MRI, and the cross-sectional area differences of bilateral psoas major muscle (BPMM) and multifidus muscle of the patients before and after therapy were evaluated. The visual analog scale (VAS) and Japanese Orthopaedic Association (JOA) scores of the two groups before and after therapy were compared, and the associations of the cross-sectional area differences of BPMM and multifidus muscle with efficacy, VAS score, and JOA score were analyzed. According to MacNab criteria, the clinical efficacy on the patients was evaluated, on which the patients were grouped. In addition, logistic regression analysis was performed for analyzing risk factors of clinical efficacy, and receiver operating characteristic (ROC) curves were drawn for analyzing the value of risk factors with differences in clinical efficacy evaluation. Results. The Obs group presented larger cross-sectional area differences of BPMM and multifidus muscle than the Con group (both P < 0.05 ). At 6 months after surgery, the Obs group showed a superior rate of 83.33%. In this group, patients with a superior efficacy showed smaller cross-sectional area differences of BPMM and multifidus muscle before surgery and at 6 months after surgery and got lower VAS scores and higher JOA scores than those without a superior efficacy (all P < 0.05 ). According to Pearson’s correlation analysis, the cross-sectional area differences of BPMM and multifidus muscle before surgery and at 6 months after surgery were positively associated with VAS score and negatively associated with JOA score (both P < 0.05 ). According to logistic regression analysis, the cross-sectional area differences of BPMM and multifidus muscle were risk factors impacting the patients’ prognosis. ROC curve-based analysis revealed that the cross-sectional area differences could be adopted as evaluation indexes for clinical efficacy on patients. Conclusion. The cross-sectional area differences of BPMM and multifidus muscle can serve as reference indexes for evaluating the postoperative efficacy on patients with LDH.

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“…The early ossification of fetal skull represents another challenge [36,37] . Therefore, magnetic resonance imaging [MRI] has come into practice, with its advantages of better soft tissue contrast resolution, larger field of view and opportunity to obtain multiplane images make fetal MRI an important diagnostic tool [38] .…”

Section: Discussionmentioning

confidence: 99%

Ultrasonographic Evaluation of Fetal Brain Midline Structures in The Second Trimester: The role of 2D versus 4D, with Post-Natal Correlation

Salam

Mustafa

Sayed

et al. 2021

International Journal of Medical Arts

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Background: Midline cerebral structures are essential for the normal morphogenesis and function of the fetal brain. However, the diagnosis of congenital anomalies of midline cerebral structures. The Aim of The Work:This study aimed to evaluate the role of 2D versus 4D ultrasound in the diagnosis of midline structures of the fetal brain at the second trimester of pregnancy.Patients and Methods: 200 pregnant women at the second trimester [18-22 weeks] were selected. They were clinically evaluated to check the female and fetal wellbeing. Then a screening of fetal brain midline strictures had been performed by two-and four-dimensional ultrasound, aiming to discover any anomalies of the fetal brain midline structure. Both scans were compared with the postnatal transcranial ultrasound. Results:The 2D ultrasound detected no abnormality in 194 out of 200 fetuses [97.0%], and 4 cases [2.0%] had mega-cisterna magna, and 2 cases [1.0%] had encephalomylocele, which were detected by the 4 D and confirmed by postnatal transcranial ultrasound. The 4 D US discovered 2 cases [1.0%] of Dandywalker malformation, which was confirmed by postnatal transcranial US. There was a complete agreement between prenatal 4D ultrasound and postnatal transcranial ultrasound. The prenatal 2D ultrasound had a sensitivity of 75.0%, specificity of 100.0%, PPV of 100.0%, NPV of 98.7% and overall accuracy of 99.0%. Otherwise, the prenatal 4D ultrasound was 100.0% sensitive and specific. Conclusion:4D ultrasound showed superiority in the diagnosis and confirmation of the fetal brain midline structure's abnormalities. Also, the prenatal 4D ultrasound was 100.0% sensitive as postnatal transcranial US.

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Fetal MRI of CNS abnormalities

Cited by 26 publications

References 9 publications

Quantitative Evaluation of a Cross-Sectional Area of the Fetal Straight Sinus by Magnetic Resonance Imaging and Its Clinical Value

Quantitative Evaluation of a Cross-Sectional Area of the Fetal Straight Sinus by Magnetic Resonance Imaging and Its Clinical Value

Value of Lumbar MRI Parameters in the Evaluation of Postoperative Curative Effect on Patients with Lumbar Disc Herniation and Analysis of Risk Factors

Ultrasonographic Evaluation of Fetal Brain Midline Structures in The Second Trimester: The role of 2D versus 4D, with Post-Natal Correlation

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