Field Use and Evaluation of a Vaccine for Bovine Staphylococcic Mastitis

Oehme, F W; Coles, Embert H.

doi:10.3168/jds.s0022-0302(67)87717-8

Cited by 6 publications

(2 citation statements)

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“…agalactiae and Staph. aureus and although potential efficacy was shown in laboratory experiments, early field trials failed to demonstrate that immunization could reduce new IMI (Oehme and Coles, 1967;Mellenberger, 1977). While several Staph.…”

Section: Other Important Preventive Strategiesmentioning

confidence: 99%

A 100-Year Review: Mastitis detection, management, and prevention

Ruegg

2017

Journal of Dairy Science

647

475

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Mastitis is the most frequent disease of dairy cows and has well-recognized detrimental effects on animal wellbeing and dairy farm profitability. Since the beginning of modern dairy farming, producers have sought effective methods to minimize the occurrence of mastitis in their herds. The objective of this paper is to review and highlight important advances in detection, management, and prevention of mastitis that have occurred since the first volume of the Journal of Dairy Science was published in 1917. Initial research efforts were directed at understanding the nature of pathogenic bacteria that were responsible for most intramammary infections. For decades, researchers worked to identify effective strategies to control mastitis caused by Streptococcus agalactiae and Staphylococcus aureus. To develop successful control programs, mastitis workers first had to identify mechanisms of infection, define the clinical and subclinical states of the disease, discover appropriate screening tests, determine likely points of exposure, identify pathogen-specific characteristics, and develop effective procedures for machine milking. Pioneering researchers eventually recognized that mastitis control was based on preventing new infections from occurring in healthy cows and reducing the duration that cows remained infected. Development of a control program that incorporated post-milking teat dipping, hygienic milking procedures, and strategic use of antibiotic therapy at dry-off resulted in widespread control of contagious pathogens. As herd management changed, researchers were tasked with defining control of mastitis caused by opportunistic pathogens originating from environmental sources. As mastitis pathogens have evolved, researchers have sought to define antimicrobial usage that will maintain animal wellbeing while minimizing unnecessary usage. During the last century, tremendous significant advances in mastitis control have been made but changing herd structure and more rigorous processor standards ensure that mastitis will remain an important subject focus of future research.

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Section: Other Important Preventive Strategiesmentioning

confidence: 99%

A 100-Year Review: Mastitis detection, management, and prevention

Ruegg

2017

Journal of Dairy Science

647

475

View full text Add to dashboard Cite

show abstract

“…The results indicated that local production of immunoglobulins close to the glandular epithelium created a concentra- tion gradient with the highest concentration immediately adjacent to the basal membrane of the epithelial cell. In this situation preferential transfer of IgA and IgM across the glandular epithelium could occur without the necessity for specific receptor sites as postulated for selective transfer of D. Immunity to staphylococcal mastitis Numerous attempts have been made in the past to immunize ruminants against the commonly occurring staphylococcal mastitis by administering staphylococcal vaccines parenterally (Derbyshire 1962, Cameron 1964, Oehme & Coles 1967, Lepper 1967, Skean & Overcast 1968. Generally these attempts have been unsuccessful probably because blood antibody passes into milk in significant quantities only after the mammary gland epithelium becomes inflamed , Mackenzie & Lascelles 1968.…”

Section: Lascelles and Mcdowellmentioning

confidence: 99%