Fine needle aspiration biopsy in clinical management of head and neck tumors

Flynn, Michael B.; Wolfson, Stewart E.; Thomas, S.; Kuhns, James G.

doi:10.1002/jso.2930440405

Cited by 28 publications

(17 citation statements)

References 9 publications

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“…Nondiagnostic and inadequate smears have been reported in 2-10% of cases in the literature [2]; in our cases we observed 5 of 70 (7%) inadequate smears. We excluded these inaccurate results from the statistical analysis the same as several previous studies [8,9,14,15]. In those studies, a test was interpreted just when it was done properly.…”

Section: Discussionmentioning

confidence: 99%

Value of Fine-Needle Aspiration Cytology in the Evaluation of Parotid Tumors

Javadi

Asghari

Hassannia

2011

Indian J Otolaryngol Head Neck Surg

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Fine needle aspiration cytology (FNAC) is commonly used in the study of parotid masses; however controversy exists regarding its diagnostic accuracy. The objective of this study was to evaluate the effectiveness of FNAC as a preoperative diagnostic tool of parotid tumors. Sixty-five patients had satisfactory preoperative FNAC and underwent subsequent surgery to the parotid between March 2002 and July 2009 at our institution. The results of the FNAC were compared to the permanent histopathological diagnosis. The sensitivity, specificity, positive predictive value, negative predictive value, and the overall accuracy of FNAC for parotid masses were 57.9, 97.8, 91.7, 84.9, and 86%, respectively. FNAC is useful in the preoperative assessment of parotid tumors and surgical planning. The non-diagnostic and false-negative results are the limitations of FNAC that should be reduced to improve its usefulness in the evaluation of parotid tumors.

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Section: Discussionmentioning

confidence: 99%

Value of Fine-Needle Aspiration Cytology in the Evaluation of Parotid Tumors

Javadi

Asghari

Hassannia

2011

Indian J Otolaryngol Head Neck Surg

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“…FNA biopsy is more convenient for the patient and their families, with minimal loss of time from work. 3,19 It also reduces the need to perform excision biopsy in many cases, which often requires time off from work, preoperative blood tests, and radiologic testing. In the pediatric population, FNA helps save children from having to undergo anesthesia and from suffering the complications of excision biopsy.…”

Section: Fna Biopsy For Pediatric Head and Neck Lesionsmentioning

confidence: 99%

Evaluation of fine needle aspiration biopsy as a diagnostic tool in pediatric head and neck lesions

Dutta¹,

Awasthi²,

Agarwal³

et al. 2010

PLMI

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Background: Fine needle aspiration (FNA) biopsy is a well accepted diagnostic procedure and considered to be a valuable test for initial assessment of head and neck swellings in adults. The technique has gained popularity in the pediatric population over the last decade, with varying degrees of acceptance rates, accuracy, and results among pathologists. Objective: This study was performed to evaluate the utility of aspiration cytology as a first-line diagnostic tool in palpable head and neck masses in children, taking into account the diversity of lesions observed in this subset of the population. Cytologic analysis was correlated with histologic results for evaluating diagnostic accuracy wherever possible. The applicability of FNA biopsy in diagnosing pediatric malignant lesions was also evaluated. Methods: This retrospective study conducted from January 2008 to December 2009 screened all pediatric cases referred to the departments of pathology at two tertiary care hospitals in India. Data from a total of 662 children aged 0-15 years presenting with head and neck masses who underwent FNA biopsy were collected. Cytologic results were interpreted and analyzed according to anatomic site. The lesions were then categorized into inflammatory, infective, and neoplastic. Results: Of the 662 lesions, 23 cases were excluded due to inadequate material, thus the data for 639 cases were finally evaluated. Lymph node lesions predominated, accounting for 570 cases (89.2%), of which 412 (72%) cases were diagnosed as reactive and 91 (16%) cases as tubercular lymphadenitis. Other lesions aspirated were thyroid (18 cases, 2.8%), salivary gland (12 cases, 1.8%), and miscellaneous surface lumps (39 cases, 6.1%). Of all the cases, 628 (98.27%) were reported as benign and 11 (1.67%) as malignant. The positive predictive value of cytologic analysis in diagnosing malignancy was 100%, although exact typing of lesions was possible only on histopathologic examination. Conclusion: FNA biopsy is a sensitive and minimally invasive first-line investigation in the diagnosis of head and neck masses in children. It is highly accurate in isolating and determining potentially neoplastic lesions, thus guiding the way for cases which truly require excision biopsy or other second-line investigations.

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“…4,5,7,9 In our study, we showed that ultrasound guidance increased the adequacy (diagnostic yield), sensitivity, and accuracy of neck mass FNC to 94%, 97%, and 96%, respectively. Most strikingly, the accuracy of diagnosing malignant neck masses reached 98% in our study, with a positive predictive value of 98% in 48 malignant cancers, including metastases (P = .023).…”

Section: Discussionmentioning

confidence: 48%

“…3 Therefore, a proper and minimally invasive means of diagnosing a neck mass is crucial for effective treatment planning. Two fine-needle biopsy (FNB) techniques have been widely used in clinical settings with promising diagnostic benefit as outpatient procedures [4][5][6][7] : fine-needle aspiration biopsy (FNA) and fine-needle capillary sampling biopsy (FNC). Of these, FNC, also known as the French biopsy technique, is a type of FNB technique that involves repetitive passes of a 25-gauge needle through the neck mass.…”

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confidence: 99%

How Diagnostic Is Ultrasound-Guided Neck Mass Biopsy (Fine-Needle Capillary Sampling Biopsy Technique)?

Lee

Chen

Sauk

et al. 2009

Journal of Ultrasound in Medicine

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Objective. The purpose of this study was to evaluate the diagnostic value of ultrasound-guided neck mass biopsy (fine-needle capillary sampling biopsy [FNC] The most biopsied location was in the lymph nodes (34.8%), followed by perithyroid soft tissue masses (28.0%). A 25-gauge needle was used most frequently (97.7%). A total of 41 biopsies were diagnostic for thyroid diseases (31.1%), with the most common being thyroid papillary carcinoma. We found metastases in 31 biopsies (23.5%). Following these 2 were 29 lymph node biopsies. No major complications were noted. Of the 132 neck masses biopsied, 8 were pathologically nondiagnostic (93.9% diagnostic yield), yielding sensitivity, specificity, and accuracy of greater than 95% (97.1%, 95.2%, and 95.8%, respectively). Conclusions. Ultrasound-guided FNC of neck masses is highly diagnostic. The diagnostic yield is especially high for detection of malignancy, including metastases. Together with a high clinical suspicion, ultrasound-guided needle biopsy should be performed to form a correct diagnosis and make appropriate management plans.

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Fine needle aspiration biopsy in clinical management of head and neck tumors

Cited by 28 publications

References 9 publications

Value of Fine-Needle Aspiration Cytology in the Evaluation of Parotid Tumors

Value of Fine-Needle Aspiration Cytology in the Evaluation of Parotid Tumors

Evaluation of fine needle aspiration biopsy as a diagnostic tool in pediatric head and neck lesions

How Diagnostic Is Ultrasound-Guided Neck Mass Biopsy (Fine-Needle Capillary Sampling Biopsy Technique)?

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