Fine Needle Aspiration Cytology of Lymph Nodes in Hiv Infected Patients

Satyanarayana, S; Kalghatgi, AT; Muralidhar, Akshay; Prasad, RS; Jawed, KZ; Trehan, A

doi:10.1016/s0377-1237(02)80010-7

Cited by 17 publications

(25 citation statements)

References 10 publications

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“…Satyanarayana et al 14 reported a reactive cytomorphological pattern in 16.4% of their cases of tuberculosis, which is lower than our study.…”

Section: Reactive Lymphadenopathycontrasting

confidence: 90%

Study of Prevalence of Granulomatous Lymphadenitis in Individuals Affected With Hiv Infection

Rao¹,

Aparna²,

Murthy³

et al. 2017

jemds

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BACKGROUNDPrevalence of Granulomatous lymphadenitis in human immune deficiency virus infection is increasing drastically in developing countries, particularly in India. In the present study, an attempt has been made to find an association of Granulomatous lymphadenitis in human immune deficiency virus infection in humans.The aim of this study is to correlate the FNAC finding with clinical, radiological and morphological patterns like correlation with findings and the CD4 count, relation of Mantoux to lymph nodes and relation with x-ray findings. MATERIALS AND METHODSA descriptive study done in 100 adult patients, aimed to study the prevalence of tuberculous lymphadenitis by cytological patterns in lymph nodes of HIV sero-positive patients by collecting and studying material through FNAC and clinical importance by Mantoux and x-ray findings. Patients attending Government General Hospital, ACSR GMC, Nellore who was not on ATT or ART were chosen for the study. RESULTSVarious lesions were observed in this study. Granulomatous lymphadenitis was observed in 74 cases, reactive lymphadenitis was seen in 22 cases and acute suppurative lymphadenitis was seen in 3 cases. One case has shown secondary deposits of squamous cell carcinoma. CONCLUSIONFNAC is a relatively inexpensive initial investigative technique important for assessing the cause of lymphadenopathy in HIV patients; allows a rapid diagnosis obviating the need for surgery and enabling swift treatment to be undertaken where necessary. Universal safety precautions must be strictly followed. The method is accurate, cost effective and acceptable to patients. TB is the major opportunistic infection, which could be detected in both symptomatic and asymptomatic individuals and even in tiny nodes. There was strong association with Mantoux and x-ray for diagnosing Granulomatous lesions. KEYWORDS

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“…Satyanarayana et al 14 reported a reactive cytomorphological pattern in 16.4% of their cases of tuberculosis, which is lower than our study.…”

Section: Reactive Lymphadenopathycontrasting

confidence: 90%

Study of Prevalence of Granulomatous Lymphadenitis in Individuals Affected With Hiv Infection

Rao¹,

Aparna²,

Murthy³

et al. 2017

jemds

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“…All the cases of reactive lymphadenitis were negative for AFB. Satyanarayana et al [20] in their study reported a reactive cytomorphological pattern in 16.4% of their cases of tuberculosis. Bottles et al [21] in their study on HIV lymphadenopathy mentioned that 50% aspirate showed reactive lymphoid hyperplasia, Picerno I et al [22] and Reid et al [10] found reactive hyperplasia in 41% and 51% aspirates respectively.…”

Section: Discussionmentioning

confidence: 86%

“…Shenoy et al [17] , Vanisri et al [5] and Deshmukh et al [13] also did not find any other opportunistic infection in their studies. Though, Satyanarayana et al [20] reported one case of Cryptococcus and one case of Rhodotorula in their studies.…”

Section: Discussionmentioning

confidence: 95%

Fnac of Hiv Lymphadenopathy in a Tertiary Care Hospital: A Two Year Study

Surase¹,

Deka²,

Solanke³

et al. 2016

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The incidence of Human Immunodeficiency Virus (HIV) infection is seen to be increasing in Asia, particularly in the Indian subcontinent. Immune system and the central nervous system are the two major targets of this infection. HIV infection is often associated with a number of opportunistic infections and malignancies, presenting with lymphadenopathy which is one of the earliest manifestations of HIV infection. Hence, this study was done to evaluate the diagnostic utility of Fine Needle Aspiration Cytology (FNAC) for HIV positive lymphadenopathy patients and to analyse the different cytological diagnostic patterns of lymph node lesions in HIV/AIDS patients. MATERIALS AND METHODSA total of 70 cases were studied in this prospective study. Fine needle aspiration was done. Both alcohol fixed and air dried smears were prepared. Lymph node aspirates were stained with Haematoxylin and Eosin (H&E), Papanicolaou's stain (PAP), Giemsa and Ziehl and Neelsen (ZN) stain. All these stains were done in all the cases irrespective of the cytological findings. RESULTS AND DISCUSSIONIn the present study, out of 70 HIV positive patients, 40 (57.14%) were males and 30 (42.86%) were females with a male-tofemale ratio of 1.3:1. Maximum affected patients were seen in the age group of 31-40 years. The most common site of HIV lymphadenopathy is the cervical lymph nodes 47 (67.14%), followed by axillary 08 (11.44%), inguinal, submandibular and supraclavicular 04 (5.71%) cases each. The most common presentation was tuberculous lymphadenitis constituted about 42 (60%) cases. CONCLUSIONFNAC is reliable and inexpensive technique for evaluation and identification of opportunistic infections, neoplastic lesions and non-neoplastic lesions. In HIV patients, it helps in segregating cases which requires further evaluation. This is a quick and repeatable procedure which spare patients from lymph node excision and enable immediate treatment of specific infection.

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“…Satyanarayana et al [12], in a study of fine needle aspiration cytology (FNAC) of lymph nodes in 196 HIV-positive patients demonstrated acid fast bacilli (AFB) with equal frequency in both symptomatic and asymptomatic groups. This suggests that many of the cases of generalised lymphadenopathy in HIV positive patients are tubercular in aetiology.…”

Section: Discussionmentioning

confidence: 99%

Lymphoreticular Involvement in Human Immunodeficiency Virus Infection

Sawhney

2008

Medical Journal Armed Forces India

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Fine Needle Aspiration Cytology of Lymph Nodes in Hiv Infected Patients

Cited by 17 publications

References 10 publications

Study of Prevalence of Granulomatous Lymphadenitis in Individuals Affected With Hiv Infection

Study of Prevalence of Granulomatous Lymphadenitis in Individuals Affected With Hiv Infection

Fnac of Hiv Lymphadenopathy in a Tertiary Care Hospital: A Two Year Study

Lymphoreticular Involvement in Human Immunodeficiency Virus Infection

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