Five-membered N-Heterocycles Synthesis Catalyzed by Nano-silica Supported Copper(II)–2-imino-1,2-diphenylethan-1-ol Complex

Phosphomolybdic acid supported on Schiff base functionalized graphene oxide nanosheets: Preparation, characterization, and first catalytic application in the multi‐component synthesis of tetrahydrobenzo[a]xanthene‐11‐ones

“…These compounds, either alone or in a metal chelated form, are widely applied as antioxidant, anticonvulsant, antihypertensive α‐blocking agent, and in cancer diagnosis . In recent years, SBs derived from aromatic (benzene) rings containing carbonyl groups such as benzil or benzil like compounds, salicyaldehyde, and benzoin are widely used in functionalization of nanomaterials . These SB functionalized nanomaterials are used for different kinds of applications in catalysis, CO 2 capture for environmental clean‐up, antibacterial agents, fabrication of polymer nanocomposites, and electromagnetic studies …”

Silica‐supported Cu(II)–quinoline complex: Efficient and recyclable nanocatalyst for one‐pot synthesis of benzimidazolquinoline derivatives and 2H‐indazoles

“…In continuation, ring closure takes place by the nucleophilic attack of the NH 2 group. Finally, oxidation process can convert the intermediate V to corresponding product (Figure ) …”

“…In the past decade, a great deal of attention has focused on copper‐based nanocatalysts because of their high activity and selectivity in various organic reactions including multicomponent, cross‐coupling and click reactions . These Cu(II)‐based catalysts are readily available, of low cost, stable in air and can be easily handled in comparison to other transition metal catalysts .…”

An Efficient Ultrasound Promoted Three‐Component and Regioselective Synthesis of Indenoquinoxaline Compounds Containing Pyrrolopyrimidine Skeleton

“…The term MCRs (multicomponent reactions) offers an efficient and one‐pot pathway to construct densely functionalized targets from simple and readily available substrates. The MCRs also have the benefits including high atom economy, high chemical yields, selectivity, and flexibility . Furthermore, MCRs are of notable significance in chemical, medicinal and pharmaceutical laboratories and have been known as one of the most powerful synthetic tools due to high efficiency in the construction of heterocyclic frameworks with high molecular complexity and diversity ,…”

“…The MCRs also have the benefits including high atom economy, high chemical yields, selectivity, and flexibility. [5][6][7] Furthermore, MCRs are of notable significance in chemical, medicinal and pharmaceutical laboratories and have been known as one of the most powerful synthetic tools due to high efficiency in the construction of heterocyclic frameworks with high molecular complexity and diversity. [8,9] Quinoxaline (1,4-diazanaphthalene) derivatives are well recognized for their widespread biological properties such as anti-bacterial, [10] anti-fungal, [11,12] anti-cancer, [13] anti-microbial, [14] anti-tubercular, [15] anti-depressant, [16] anti-convulsant, [17] antiinflammatory, [18] anti-malarial, [19] anti-hypertensive, [20] P-glycoprotein-mediated drug efflux inhibitor, [21] anti-diabetic, [22] and anti-HIV.…”