“…These potential benefits, however, must be weighed against the risk of low-quality, non-peer-reviewed research fueling media-driven panic or resulting in inappropriate clinical and policy decisions based on erroneous data, which both could cause harm to individuals and compromise scientific integrity. [29][30][31][32] Even articles published in reputable journals have been retracted, including from Annals of Internal Medicine, 33 The Lancet, 34,35 and The New England Journal of Medicine. 36 A recent review reports that, despite the large number of publications, only a fraction of the published studies fulfilled the principles of evidence-based practice.…”