Flavanol Derivatives from Rhizophora stylosa and Their DPPH Radical Scavenging Activity

Li, Dongli; Li, Xiaoming; Peng, Zeyu; Wang, Bin‐Gui

doi:10.3390/12051163

Cited by 37 publications

(33 citation statements)

References 18 publications

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“…The tannins are able to donate electrons to free radicals, stabilize them, and alleviate harmful radical structures [24]. Several studies have also demonstrated the free radical scavenging activity of the condensed tannins [18,19,25,26]. Therefore, mangrove fruit which is abundant in the condensed tannins must be the potential antioxidant agent.…”

Section: Antioxidant Activitymentioning

confidence: 99%

The Bioactive Compounds and Antioxidant Activity of Food Products of Rhizophora stylosa Fruit (Coffee and Tea Mangrove)

Miranti¹,

Ichiura²,

Ohtani³

2018

International Journal of Forestry Research

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The objective of this study is to investigate the bioactive compounds and antioxidant activity of coffee and tea mangrove (locally known in Indonesia) produced from the fruit of Rhizophora stylosa. Furthermore, three raw materials of coffee mangrove were also investigated to clarify their potencies. The crude extracts of five samples were subjected to antioxidant assay using DPPH. The results show that the extract of tea mangrove has the strongest activity; then, it was successfully fractionated using different polarity of solvents and yielded acetone and methanol fractions that had high antioxidant activity. The acetone fraction was purified and gave fractions A1, A2, A3, A4, A5, and A6, but only A2 and A3 indicated antioxidant activity and, therefore, they were subjected to further purification. Fractions A3 (caffeine) and A2 gave AS1 (N,N-dimethyl-L-alanine), AS2 (quercetin-3-O-galactopyranoside), AS3 (dodecanoic acid), and AS4 that had the similar 1 H-NMR spectrometric results with AS2, while the methanol fraction did not exhibit clear peaks on the chromatogram by HPLC. Therefore, the precipitation method was conducted to purify this fraction, and the precipitate was analyzed by NMR spectra. The results from 1 H and 13 C NMR indicate that this fraction is a typical polymer of condensed tannins, containing procyanidin and prodelphinidin units.

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Section: Antioxidant Activitymentioning

confidence: 99%

The Bioactive Compounds and Antioxidant Activity of Food Products of Rhizophora stylosa Fruit (Coffee and Tea Mangrove)

Miranti¹,

Ichiura²,

Ohtani³

2018

International Journal of Forestry Research

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“…Amongst the flavanols isolated, proanthocyanidin B2, epicatechin + catechin and cinchona in Ib had DPPH radical scavenging ability with IC 50 values of 4.3, 6.5 and 7.8 µg/ml, respectively (Li et al, 2007). Proanthocyanidin B2 (4.3 μg/ml) with the strongest free radical scavenging activity was 4.2 times stronger than butylated hydroxytoluene (18 μg/ml), the positive control.…”

Section: Resultsmentioning

confidence: 91%

“…The potent antioxidant properties of stems of R. stylosa could be attributed to flavanols (Li et al, 2007;Takara et al, 2008) and pentacyclic triterpenoids (Li et al, 2008). Amongst the flavanols isolated, proanthocyanidin B2, epicatechin + catechin and cinchona in Ib had DPPH radical scavenging ability with IC 50 values of 4.3, 6.5 and 7.8 µg/ml, respectively (Li et al, 2007).…”

Section: Resultsmentioning

confidence: 99%

Antioxidant, anti-tyrosinase and anti-quorum sensing activities of four mangrove tree species vs. green tea

Chan¹,

Ng²,

Sim³

et al. 2017

J App Pharm Sci

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This study was conducted to validate a claim that mangrove teas have stronger antioxidant and anti-tyrosinase properties than green tea. Different plant parts (leaves, stems and roots) of four mangrove tree species namely Rhizophora apiculata, Rhizophora stylosa, Avicennia rumphiana and Sonneratia alba were analysed their antioxidant, anti-tyrosinase and anti-quorum sensing (anti-QS) properties. Strongest antioxidant properties were observed in the stems of R. stylosa. Antioxidant properties of the mangrove species (fresh samples) and their teas (dried leaves) were inferior to leaves of Camellia sinensis and green tea, respectively. The anti-tyrosinase activity of leaves and stems of R. apiculata, and stems of S. alba was outstanding but was not detected in green tea. All four mangrove species possessed anti-QS properties with moderate activity displayed by green tea.

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“…proantosianidin B2 dari ekstrak metanol batang dan ranting R. stylosa [4]. Kemudian dua senyawa golongan steroid yang diisolasi dari ekstrak kloroform kulit batang R. mucronata yaitu 4-metil-kolest-24-en-3-ol dan 4-metilstigmast-22-en-3-ol.…”

Section: Pendahuluanunclassified

Phytochemical Test and Antibacterial Test of Rhizopora apiculata Mangrove-Root against Escherichia coli and Staphylococcus aureus Bacteria

Usman

2018

JKPK

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ABSTRAKIndonesia memiliki berbagai jenis mangrove namun pemanfaatan mangrove sebagai produk obat dan makanan kesehatan belum banyak dimanfaatkan karena masih terbatasnya informasi dan penelitian mengenai kandungan senyawa bioaktif pada tumbuhan mangrove. Salah satu spesies mangrove yang banyak ditemukan di kawasan hutan mangrove Bontang Kalimantan Timur adalah R. apiculata. Tumbuhan ini dimanfaatkan oleh masyarakat pesisir sebagai bahan bakar, bahan bangunan, bahan pembuatan kapal, dan sebagai bahan obat tradisional. Penelitian ini bertujuan untuk mengetahui golongan senyawa metabolit sekunder dan aktivitas antibakteri ekstrak metanol akar mangrove R. apiculata. Ekstraksi dilakukan dengan metode maserasi dengan menggunakan pelarut metanol. Golongan senyawa metabolit sekunder yang terkandung pada sampel mangrove tersebut ditentukan secara kualitatif dengan menggunakan beberapa pereaksi uji fitokimia. Metode yang digunakan untuk uji antibakteri terhadap E. coli dan S. aureus adalah metode difusi dengan variasi konsentrasi ekstrak metanol akar mangrove R. apiculata 500 μg/well, 250 μg/well, dan 125 μg/well serta variasi waktu inkubasi 12 jam, 24 jam, 48 jam, dan 72 jam. Berdasarkan hasil uji Fitokimia dapat disimpulkan bahwa ekstrak metanol akar mangrove R. apiculata mengandung golongan senyawa metabolit sekunder: alkaloid, flavonoid, dan triterpenoid. Hasil uji antibakteri ekstrak metanol akar mangrove R. apiculata mampu menghambat pertumbuhan bakteri S. aureus pada konsentrasi 500 µg/well dengan waktu inkubasi 12 jam, 24 jam, 48 jam, dan 72 jam dengan zona hambat masing-masing 7.95 mm, 8.3 mm, 8.0 mm, dan 7.0 mm. Pada konsentrasi 250 µg/well dengan waktu inkubasi 48 jam memiliki zona hambat 7.5 mm. Namun ekstrak metanol akar mangrove R. apiculata tidak menghambat pertumbuhan bakteri Escherichia coli. Berdasarkan data zona hambatan pada uji antibakteri terhadap S. aureus dapat disimpulkan bahwa aktivitas antibakteri ekstrak metanol akar mangrove R. apiculata terhadap S. aureus tergolong kategori lemah. Kata kunci: Rhizophora apiculata, senyawa metabolit sekunder, antibakteri ABSTRACTIndonesia has many kinds of mangrove but they have not been widely utilized as health food and medicinal products because of the limited information and research on the content of bioactive compounds in the mangroves. One of the mangrove species that are found in the

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Flavanol Derivatives from Rhizophora stylosa and Their DPPH Radical Scavenging Activity

Cited by 37 publications

References 18 publications

The Bioactive Compounds and Antioxidant Activity of Food Products of Rhizophora stylosa Fruit (Coffee and Tea Mangrove)

The Bioactive Compounds and Antioxidant Activity of Food Products of Rhizophora stylosa Fruit (Coffee and Tea Mangrove)

Antioxidant, anti-tyrosinase and anti-quorum sensing activities of four mangrove tree species vs. green tea

Phytochemical Test and Antibacterial Test of Rhizopora apiculata Mangrove-Root against Escherichia coli and Staphylococcus aureus Bacteria

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