“…The activity of the plant against both Grampositive and Gram-negative bacteria may be indicative to the presence of broad spectrum antibiotic compounds or simply general metabolic toxins in the plant, in addition to the plant (fruits, leaves and root) content of pharmacological active metabolites like furostanol and spirostanol saponins (Kostova and Dinchev, 2005), flavonoid glycosides (Saleh et al, 1982), phytosterols and some amides (Xu et al, 2000). The plant also contains a mixture of Bcarboline alkaloids: harmane, norharmane, tetrahydroharmane, harmine, harmaline, harmol, harmalol, ruin and dihydroruin (Bourke et al, 1990).…”