Flavonoids and anthraquinones of some Egyptian Rumex species (Polygonaceae)

Saleh, Nabiel A.M.; El-Hadidi, M.N.; Arafa, Raafat F.M.

doi:10.1016/0305-1978(93)90049-w

Cited by 35 publications

(20 citation statements)

References 3 publications

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“…The presence of the ion [M−H−18] − in compounds 3 , 10 , 12 indicated the position of the C‐glycosylation at C‐6. The absence of this latter ion indicated a C‐8 glycosylation in compounds 1 and 2 ; comparing these results and UV absorbance with that of authentics and literature data (Ferreres and others 2006; Krasteva and Nocolov 2008), they were identified as 8‐C‐glucosyl‐apigenin (vitexin) 1 , 8‐C‐glucosyl‐luteolin (orientin) 2 that were previously identified by Saleh and others (1993), and 6‐C‐hexosyl‐quercetin 3 , 6‐C‐hexosyl‐naringenin 10 , 6‐C‐hexosyl‐catechin 12 . In MS2 of O‐glycosides, compound 4 showed a deprotonated molecular ions at m/z 609 [M−H] − and a peak of the aglycone due to loss of sugar part 301 (100%, [A−H] − ) were characteristic to rutin (Ferreres and others 2006).…”

Section: Resultssupporting

confidence: 61%

A Profile of Bioactive Compounds of Rumex vesicarius L.

El‐Hawary¹,

Sokkar²,

Ali³

et al. 2011

Journal of Food Science

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The present study was designed to investigate the bioactive compounds in extracts of Rumex vesicarius L. (Polygonaceae), a wild edible herb growing in Egypt. Ethyl acetate and n-butanol fractions of leaves of R. vesicarius were conducted by HPLC-PDA-MS/MS-ESI in the negative mode to analyze phenolics content. Results revealed the identification of 13 phenolic compounds: 8-C-glucosyl-apigenin, 8-C-glucosyl-luteolin, 6-C-hexosyl-quercetin, 3-O-rutinosyl-quercetin, 7-O-rhamno-hexosyl-diosmetin, 7-O-rhamno-acetylhexosyl-diosmetin, catechin, epicatechin, ferulohexoside, 6-C-glucosyl-naringenin, epicatechin gallate, 6-C-glucosyl-catechin, and epigallocatechin gallate. Quantification of the identified compounds revealed that 6-C-glucosyl-naringenin was the major compound. Also, qualitative and quantitative analysis of the hydro-ethanolic extract of leaves was carried out for ascorbic acid, α-tocopherol, β-carotene. The essential oil as well as lipids analysis of saponifiable and unsaponifiable matters. The biochemical studies were conducted to evaluate the antioxidant and hepatoprotective potential of roots (REE), leaves (LEE), and fruits (FEE) ethanolic extracts of R. vesicarius (100 mg/kg b.wt., p.o., each) against hepatotoxicity induced by CCl(4) (0.5 mL/kg b.wt., p.o., 3 times a week) compared with silymarin (50 mg/kg b.wt., p.o.) as standard drug. The results confirmed that coadministration of the tested extracts or silymarin with CCl(4) for 4 wk exhibited a marked hepatoprotective activity, attributed to their antioxidant potential, membrane stabilizing effect, and antifibrogenic activities. Practical Application: Investigation of the effect of hommad as a safe hepatoprotective diet that prospectively directs the attention to a valuable therapeutic natural herb rich in bioactive constituents.

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Section: Resultssupporting

confidence: 61%

A Profile of Bioactive Compounds of Rumex vesicarius L.

El‐Hawary¹,

Sokkar²,

Ali³

et al. 2011

Journal of Food Science

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“…The medicinal importance of this genus is a reflection of its chemical composition since plants contain many bioactive substances such as flavonoids (vitexin, isovitexin, orientin and isorientin) (Saleh et al 1993). Rumex is also rich in anthraquinones, particularly in roots (emodin and chrysophanol).…”

Section: Introductionmentioning

confidence: 99%

Enhancement of phenolic compounds production in in vitro grown Rumex cyprius Murb.

et al. 2016

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Plant tissue culture can readily be applied to the field of medicinal plants and secondary metabolites production. In this study, in vitro propagation protocol of Rumex cyprius Murb. was established. The highest shoot multiplication rate was observed from explants grown on MS medium supplemented with 1.5 mg/L BA (7.8 shoots per explant). For rooting, the maximum root induction rate was observed on MS medium supplemented with 1.5 mg/L IBA or 1.0 mg/L NAA. The longest roots were observed for plants grown on MS medium supplemented with 1.5 mg/L IBA. For callus induction, leaves from in vitro grown plants were cultured in various levels of 2,4-D or different combinations of BA and NAA. The highest fresh weight (5.86 g) of calli was observed at 1.5 and 0.5 mg/L BA and NAA, respectively. The second part of this work investigated the effects of abiotic factors (NaCl and Mannitol) and biotic factors (Yeast extract and Chitosan) on secondary metabolites accumulation of in vitro grown R. cyprius. Phenolic compounds were extracted, and the individual phenolic compounds and antioxidant activity of the extracts were determined of in vitro grown R. cyprius. The total phenol content and antioxidant activity increased significantly by the pervious factors. Reversed high-pressure liquid chromatography (RP-HPLC) was used to measure the effect of these factors on the contents of individual phenolic compound. New phenolic compounds (Gallic acid and Chlorogenic acid) not found in R. cyprius plants grown on control media were produced in R. cyprius plants grown on media supplemented with elicitors. Results indicate that using elicitors in plant tissue culture could be used to produce/enhance secondary metabolites accumulation in R. cyprius.

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“…Plants in the Rumex genus belong to the family of Polygonaceae, and are annual or perennial herbs distributed throughout the world [1,2]. In Chinese folk medicine, plants in this genus have been used for treating various diseases from ancient times, and have medicinal functions of promoting blood circulation, removing blood stasis, detoxication, etc [2,3].…”

Section: Introductionmentioning

confidence: 99%

Effect of acetone extract of <i>Rumex japonicas</i> Houtt on hydrogen peroxide-induced apoptosis in rat myocardial cells

Zhou¹,

Cao²,

Song³

et al. 2017

Trop. J. Pharm Res

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Purpose: To investigate the protective effect of the acetone extract of Rumex japonicas Houtt. (AER) on rat myocardial cells. Methods: R. japonicas was extracted with 75 % aqueous ethanol by reflux to afford total extract (TER H2O2 (p < 0.05, p < 0.01, p < 0.01, respectively). AER (50, 100 and 200 μg/mL) decreased LDH and CK contents of H9c2 cells (p < 0.01). The levels of SOD (p<0.01) and CAT (p < 0.01) were increased by AER treatments (100 and 200 μg/mL); in addition, AER (50, 100 and 200 μg/mL) decreased MDA levels (p < 0.01

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Flavonoids and anthraquinones of some Egyptian Rumex species (Polygonaceae)

Cited by 35 publications

References 3 publications

A Profile of Bioactive Compounds of Rumex vesicarius L.

A Profile of Bioactive Compounds of Rumex vesicarius L.

Enhancement of phenolic compounds production in in vitro grown Rumex cyprius Murb.

Effect of acetone extract of <i>Rumex japonicas</i> Houtt on hydrogen peroxide-induced apoptosis in rat myocardial cells

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