Flow-sonochemiluminescence method for antioxidant capacity analysis

Two-phase dual-signal-readout immunosensing platform based on multifunctional carbon nano-onions for ovarian cancer biomarker detection

“…Firstly, the SCL signal that originates from ˙OH with strong oxidative effects is generated via the cavitation effect of water. 11 Then, the ˙OH was trapped by the ethanol in solution to produce the reduced CH 3 C˙H(OH), 29 and the CH 3 C˙H(OH) reduces O 2 and Luc 2+ , 30 producing O 2 ˙ − and Luc˙ + , respectively. 31 Lastly, the reaction between O 2 ˙ − and Luc˙ + produced the unstable dioxetane-type intermediate Luc(OO), and this intermediate decomposes to produce an excited state of N -methyl-9-acridone (NMA*) for the SCL signal.…”

“…10 Accordingly, the SCL signal generated via excitation of the acoustic cavitation effect offers great potential for sensor applications. Since ultrasound irradiation enables the generation of reactive oxygen species (ROS), 11 current SCL research is focused on analysis of the antioxidant capacity of antioxidants, including ascorbic acid, 12 bentazone, 13 etc. However, there are relatively few reports on sonochemiluminescence in the field of biosensing, due to the disadvantage of its low selectivity and the fact that the SCL signal may be too weak to meet the sensitivity requirements of the analysis.…”

Kinetics of luminol sonochemiluminescence quenched by purines

“…The 3‐aminophthalhydrazide (luminol) SCL reaction has become a useful analytical approach as an alternative for antioxidation capacity analysis . However, details of the reaction mechanism, including the number and nature of the reactive intermediates that lead to SCL, have not been fully determined.…”