Fluoride Ion Activity in vitro and in vivo of Two Sodium Fluoride Dentifrices

Jm, Birkeland

doi:10.1159/000259747

Cited by 11 publications

(5 citation statements)

References 2 publications

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“…The measured values are relative, but observations are comparable [Birkeland, 1971] (a) The standard deviation by pipetting the original 7.0 ml fluid was 0.005 g (n=10), i.e. below 0.1%.…”

Section: Sdjoo Xmentioning

confidence: 67%

“…The electrode potential (mV) of the expectorates, without any pH and buffer adjustment, was measured during stirring. The measurements (in duplicate) were compared with the fluoride ion activities (ppm F") of stand ards at pH 6.4 (solutions of sodium fluoride [Orion,] diluted with deion ized water) [Birkeland, 1971], Amount of fluoride. The total fluoride ion concentrations of the fluids were determined (in duplicate) after pH and ionic strenght adjustment (Tisab, Orion 94-09-10A; 1.0 ml sample + 1.0 ml buffer).…”

Section: Methodsmentioning

confidence: 99%

“…(3) The fluoride ion concentration in the oral fluid increases follow ing fluoride rinses [Aasenden et al, 1968;de Boever and M ühle mann, 1970;Birkeland, 1971], but observations on the clearance show concentrations of 0.19 ppm fluoride (i.e. 10~5m) about 1 h after treat ment [de Boever and M ühlemann, 1970;H assel et al, 1971a;Birkeland, 1971].…”

Section: Sdjoo Xmentioning

confidence: 99%

“…10~5m) about 1 h after treat ment [de Boever and M ühlemann, 1970;H assel et al, 1971a;Birkeland, 1971]. The possibility exists that increased retention may secondly raise the fluoride ion concentration of saliva.…”

Section: Sdjoo Xmentioning

confidence: 99%

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Intra- and Interindividual Observations on Fluoride Ion Activity and Retained Fluoride with Sodium Fluoride Mouth Rinses

Birkeland¹

1973

Caries Res

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2-min mouth rinses with 7 and 10 ml 0.05% NaF were carried out by 9 adults and 24 children (10–11 years old). Each person rinsed 5 times with , fluoride each volume. The oral expectorate with the rinsing solu tion was then weighed. The fluoride ion activity of the expectorates was determined, and retention of fluoride (μg and %) was calculated. Significantly higher fluoride ion activity with 10 than with 7 ml was obtained both by the adults (14.7 ± 6.5 ppm F^-) and the children (9.0 ± 5.7 ppm F^-). The differences in retention with 10 vs. 7 ml rinses were significant: 64 ± 30μg (n = 9) and 89 ± 81 μg (n = 24). The percentage retention with 7 ml was 15.4 ± 2.6 (n = 9) and 14.1 ± 4.8 (n = 24), the corresponding values with 10ml were 13.6 ± 2.2 and 13.8 + 3.6. Each subject seemed to have a pattern in the amount of expectorated fluid and fluoride ion activity with the 7- and 10-ml volumes, whereas no retention pattern was indicated. The findings indicate that in programs using fluoride mouth rinses, 7 ml are preferable to 10 ml, as (1) reduced amounts of swallowed fluid probably cause decreased retention and (2) the anti-caries effect seems to be equal.

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“…The measured values are relative, but observations are comparable [Birkeland, 1971] (a) The standard deviation by pipetting the original 7.0 ml fluid was 0.005 g (n=10), i.e. below 0.1%.…”

Section: Sdjoo Xmentioning

confidence: 67%

Section: Methodsmentioning

confidence: 99%

Section: Sdjoo Xmentioning

confidence: 99%

Section: Sdjoo Xmentioning

confidence: 99%

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Intra- and Interindividual Observations on Fluoride Ion Activity and Retained Fluoride with Sodium Fluoride Mouth Rinses

Birkeland¹

1973

Caries Res

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“…In the work of MCCANN (1968 a), the fluoride ion activity in saliva 10^-' mol/1 was used. Since then, it has been found that this value is a little too high and probably is closer to 10"" mol/1 (BIRKELAND 1971). A correction for this would not change the important relationship in this context.…”

Section: Discussionmentioning

confidence: 94%

Degrees of saturation with respect to apatites in parotid saliva at various pH values

Larsen¹

1975

European J Oral Sciences

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The purpose of the present work was to investigate the degrees of saturation with respect to hydroxyapatite and fluorapatite in saliva at various pH's. The data of ionic activities in parotid saliva were collected from the literature and the degrees of saturation with respect to hydroxyapatite and fluorapatite were calculated. It was found that parotid saliva was supersaturated with respect to both apatites above pH 5.5, unsaturated with respect to hydroxyapatite and concurrently supersaturated with respect to fluorapatite in the pli range 5.5-4.5, while it was unsaturated with respect to both apatites below pH 4.5. In the laboratory it has been found that when enamel is exposed to a liquid unsaturated with respect to hydroxyapatite and supersaturated with respect to fluorapatite, a caries-like lesion is developed. A liquid unsaturated with respect to both apatites leads to an erosion-like injury. It is concluded that the two chemical conditions leading to the two types of enamel lesions may both occur in the oral cavity.In previous studies, it has been shown that calcium, phosphate and fluoride sufficient enamel can be dissolved in two fundament-to supersaturate the oral fluids with respect ally different ways: when the liquid phase to the enamel mineral at physiologic pH is unsaturated with respect to both hyd-(BENEDICT & KANTHAK 1932, SCHMIDTroxyapatite and fluorapatite, both apatites NIELSEN 1946, ERICSSON 1949 dissolve coincidently, which results in an 1968a). Furthermore, it has been demonerosion-like surface etching. The other strated that saliva becomes less supersatutype of dissolution is caused by a liquid rated and even unsaturated with respect which is unsaturated with respect to hyd-to enamel when pH decreases, owing to roxyapatite and supersaturated with re-the increase-of the enamel solubility spect to fluorapatite, which causes a for- (SCHMIDT-NIELSEN 1946, ERICSSON 1949. mation of fluorapatite and a dissolution of However, how the degrees of saturation hydroxyapatite, the resulting lesion being with respect to hydroxyapatite and fluorvery like a natural caries lesion in vivo apatite in saliva change as a function of (LARSEN 1974a,b). pH has not yet been investigated. It has been shown that saliva contains Therefore, based on data collected from

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In-vitro affinity of fluoride to proteins, dextans, bacteria and salivary components

Birkeland

Rölla

1972

Archives of Oral Biology

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Fluoride Ion Activity in vitro and in vivo of Two Sodium Fluoride Dentifrices

Cited by 11 publications

References 2 publications

Intra- and Interindividual Observations on Fluoride Ion Activity and Retained Fluoride with Sodium Fluoride Mouth Rinses

Intra- and Interindividual Observations on Fluoride Ion Activity and Retained Fluoride with Sodium Fluoride Mouth Rinses

Degrees of saturation with respect to apatites in parotid saliva at various pH values

In-vitro affinity of fluoride to proteins, dextans, bacteria and salivary components

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