2-min mouth rinses with 7 and 10 ml 0.05% NaF were carried out by 9 adults and 24 children (10–11 years old). Each person rinsed 5 times with , fluoride each volume. The oral expectorate with the rinsing solu tion was then weighed. The fluoride ion activity of the expectorates was determined, and retention of fluoride (μg and %) was calculated. Significantly higher fluoride ion activity with 10 than with 7 ml was obtained both by the adults (14.7 ± 6.5 ppm F-) and the children (9.0 ± 5.7 ppm F-). The differences in retention with 10 vs. 7 ml rinses were significant: 64 ± 30μg (n = 9) and 89 ± 81 μg (n = 24). The percentage retention with 7 ml was 15.4 ± 2.6 (n = 9) and 14.1 ± 4.8 (n = 24), the corresponding values with 10ml were 13.6 ± 2.2 and 13.8 + 3.6. Each subject seemed to have a pattern in the amount of expectorated fluid and fluoride ion activity with the 7- and 10-ml volumes, whereas no retention pattern was indicated. The findings indicate that in programs using fluoride mouth rinses, 7 ml are preferable to 10 ml, as (1) reduced amounts of swallowed fluid probably cause decreased retention and (2) the anti-caries effect seems to be equal.