Fluorometric lateral flow immunoassay for simultaneous determination of three mycotoxins (aflatoxin B1, zearalenone and deoxynivalenol) using quantum dot microbeads

Li, Runxian; Meng, Chengzhen; Yang, Wen; Fu, Wei; He, Pingli

doi:10.1007/s00604-019-3879-6

Cited by 75 publications

(24 citation statements)

References 33 publications

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“…The assays provide mainly visual qualitative results, however, semi-quantitative results for any positive samples can be also achieved with dedicated handheld devices. LFDs for multi mycotoxin detection in food and feed are also available [142][143][144]. A description of different LFDs for mycotoxin detection is presented in Table 2, showing various commercial entities offering LFDs validated for OTA and aflatoxin detection in wine and grape products, among other matrices.…”

Section: Lateral Flow and Flow-through Immunoassays (Lfia Ftia)mentioning

confidence: 99%

Recent Advances in Mycotoxin Analysis and Detection of Mycotoxigenic Fungi in Grapes and Derived Products

Kizis

Vichou

Natskoulis³

2021

Sustainability

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Mycotoxins are secondary metabolites of filamentous fungi that can cause toxic effects in human and animal health. Most of the filamentous fungi that produce these mycotoxins belong to four genera, namely, Aspergillus, Penicillium, Fusarium, and Alternaria. Mycotoxigenic fungi, along with mycotoxins, create a constant and serious economic threat for agriculture in many terms, counting product losses due to crop contamination and food spoilage, as well malnutrition when considering nutritional quality degradation. Given the importance of robust and precise diagnostics of mycotoxins and the related producing fungi in the grape food chain, one of the most important agricultural sectors worldwide, the present review initially delivers a comprehensive presentation of mycotoxin reports on grape and derived products, including a wide range of commodities such as fresh grapes, raisins, wine, juices, and other processed products. Next, based on worldwide regulations’ requirements for mycotoxins, and referring to the relative literature, this work presents methodological approaches for mycotoxin determination, and stresses major methods for the detection of fungal species responsible for mycotoxin production. The principle of function and basic technical background on the available analytical and molecular biology techniques developed—including chromatography, mass spectrometry, immunochemical-based assays, biosensors, and molecular assays—is briefly given, and references for their application to grape and derived product testing are highlighted.

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Section: Lateral Flow and Flow-through Immunoassays (Lfia Ftia)mentioning

confidence: 99%

Recent Advances in Mycotoxin Analysis and Detection of Mycotoxigenic Fungi in Grapes and Derived Products

Kizis

Vichou

Natskoulis³

2021

Sustainability

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“…75 Li et al reported the simultaneous detection of three mycotoxins, aflatoxin B1 (AFB1), zearalenone (ZEN) and deoxynivalenol (DON), with the LODs of 10, 80 and 500 pg/mL with the help of fluorometric lateral flow immunoassay (LFA) using CdSe/SiO2 quantum dot microbeads. 76 Fumonisins (FMs) are mycotoxins mainly produced by Fusarium species growing on agricultural commodities in the field, at the harvest or during storage. There are different forms of fumonisins and among these, Fumonisin B1 (FMB1) is the most common naturally occurring form, followed by FMB2 and FMB3.…”

Section: •3•2 Mycotoxinsmentioning

confidence: 99%

Quantum Dots as Biosensors in the Determination of Biochemical Parameters in Xenobiotic Exposure and Toxins

Ravi

Ganesan

2020

ANAL. SCI.

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Quantum dots (QDs) have been exploited for a range of scientific applications where the analytes can be expected to have significant photoluminescent properties. Previously, the applications of QDs as nanosensors for the detection of toxics in biospecimens, especially in cases of poisoning, have been discussed. This review focuses on the applications of QDs as biosensors for the detection of phytotoxins, vertebrate and invertebrate toxins, and microbial toxins present in biospecimens. Further, the role of QDs in the measurement of biochemical parameters of patient/victim as an indirect method of poison detection is also highlighted.

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“…Previous research studies have reported on the use of QDs as the uorescence label in immunoassays. 20,21 Compared with traditional dye molecules and CG, QDs have excellent uorescence characteristics, including a wide and continuous excitation spectrum, narrow and symmetrical emission spectrum, adjustable color, high photochemical stability, long uorescence lifetime and high quantum yield. 22 QDs are also excellent uorescent label candidates because of their photoluminescence brightness, and widely applied in the life sciences, semiconductor devices, medical and health elds.…”

Section: Introductionmentioning

confidence: 99%

Development of a fluorescent immunochromatographic assay based on quantum dots for the detection of fleroxacin

Yang

Zhou

et al. 2021

RSC Adv.

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Fluorometric lateral flow immunoassay for simultaneous determination of three mycotoxins (aflatoxin B1, zearalenone and deoxynivalenol) using quantum dot microbeads

Cited by 75 publications

References 33 publications

Recent Advances in Mycotoxin Analysis and Detection of Mycotoxigenic Fungi in Grapes and Derived Products

Recent Advances in Mycotoxin Analysis and Detection of Mycotoxigenic Fungi in Grapes and Derived Products

Quantum Dots as Biosensors in the Determination of Biochemical Parameters in Xenobiotic Exposure and Toxins

Development of a fluorescent immunochromatographic assay based on quantum dots for the detection of fleroxacin

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