Follicular bronchiolitis in association with connective tissue diseases

Fortoul, Teresa I.; Cano-Valle, Fernando; Oliva, Elena; Barrios, Roberto

doi:10.1007/bf02713828

Cited by 88 publications

(44 citation statements)

References 27 publications

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“…Chest radiographs of our patient showed bilateral re ticulonodular shadows similar to those described in the literature (3). Pulmonary function tests of 21 cases in the literature of follicular bronchiolitis revealed a restrictive defect in seven, an obstructive defect in three and a mixed ventilatory defect in seven cases (2,3,9). Our case showed a mixed ventilatory defect.…”

Section: Case Reportmentioning

confidence: 94%

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Follicular Bronchiolitis Associated with Rheumatoid Arthritis.

et al. 1992

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Section: Case Reportmentioning

confidence: 94%

“…In addition to the above-mentioned pleural and pulmonary lesions, bronchiolar lesions as sociated with RA have more widely known in recent years. In 1985, Fortoul et al (2) and Yousem et al (3) reported cases of follicular bronchiolitis which is a rare pulmonary disorder associated with RA and other con nective tissue diseases.…”

Section: Introductionmentioning

confidence: 99%

Follicular Bronchiolitis Associated with Rheumatoid Arthritis.

et al. 1992

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“…Follicular bronchiolitis is primarily a histopathological diagnosis and is characterized by hyperplastic lymphoid follicles ranged along bronchioles which are consequently compressed; there is also infiltration of the adjacent bronchiolar walls and interstitium by polyclonal lymphocytes [144,145]. The exact relationship between follicular bronchiolitis, lymphocytic interstitial pneumonitis and constrictive obliterative bronchiolitis, particularly in patients with rheumatoid arthrititis in whom these pathologies may coexist, remains controversial [146].…”

Section: Follicular Bronchiolitismentioning

confidence: 99%

“…The plain chest radiograph shows nonspecific small nodular or reticulonodular opacities [145,149], but may be normal. In an HRCT study of 14 patients (12 with a connective tissue disease) with biopsy proven follicular bronchiolitis, the predominant abnormality was small nodules (3 mm diameter, but up to 12 mm in some cases) [150].…”

Section: Follicular Bronchiolitismentioning

confidence: 99%

Small airways diseases: detection and insights with computed tomography

Dm¹

2001

Eur Respir J

146

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Diseases affecting the small airways are difficult to detect by traditional diagnostic tests. Widespread involvement is needed before symptoms and abnormalities on pulmonary function testing or chest radiography become apparent. Obstruction of the bronchioles may be detected indirectly by computed tomography (CT) because regional under-ventilation results in reduced perfusion which in turn is shown as a mosaic attenuation pattern of the lung parenchyma. When there is inflammation of the bronchioles with accompanying exudate, the airways may become directly visible on CT, for example in cases of diffuse panbronchiolitis.Quantification of the various morphological features of small airways disease is possible from CT images and this increased precision has aided investigations of structure/function relationships.An understanding of the pathology and microscopic distribution of disease in relation to the airways allows some prediction of the likely computed tomography appearances in this wide spectrum of conditions, and thus helps to refine the differential diagnosis.

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“…FB has been reported in patients with rheumatoid arthritis (RA), Sjögren's syndrome, immunodeficiency syndrome, and hypersensitivity reactions. [1][2][3][4][5][6] As FB is occasionally confused with asthma or COPD, FB has also been reported with asthma. 7 There is insufficient experience regarding the treatment of FB.…”

Section: Introductionmentioning

confidence: 99%

Successful Colchicine Therapy in a Patient With Follicular Bronchiolitis Presumed to Be Asthma

Göksel¹,

Nart²,

Ergönül

et al. 2015

Respir Care

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Follicular bronchiolitis (FB) is a rare small-airway pathology that is associated mainly with connective tissue diseases. This case report presents a new, diagnosed, different airway disease in a non-smoker with rheumatoid arthritis in remission who was treated for presumed asthma, but was not controlled. She was ultimately diagnosed with FB after video-assisted thoracoscopic surgery. The clinical findings of FB were controlled successfully by colchicine after she did not respond to systemic steroid therapy. This is the first case report of FB associated with rheumatoid arthritis that responded to colchicine.

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Follicular bronchiolitis in association with connective tissue diseases

Cited by 88 publications

References 27 publications

Follicular Bronchiolitis Associated with Rheumatoid Arthritis.

Follicular Bronchiolitis Associated with Rheumatoid Arthritis.

Small airways diseases: detection and insights with computed tomography

Successful Colchicine Therapy in a Patient With Follicular Bronchiolitis Presumed to Be Asthma

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