Formulation of cartap hydrochloride crosslinked chitosan tripolyphosphate nanospheres and its characterization

Kaur, Ishtpreet; Goyal, Dinesh; Agnihotri, Shekhar

doi:10.1007/s00396-021-04866-x

Cited by 10 publications

(1 citation statement)

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“…Nanospheres are solid hollow particles with diameter in nanometer range and their empty core posses' great potential for encapsulation of guest molecules [29]. These nanoparticle insecticide formulations can be readily dispersed in solution, which helps in eliminating the problems associated with leaching and drifting.…”

Section: Introductionmentioning

confidence: 99%

Fabrication of chitosan–alginate nanospheres for controlled release of cartap hydrochloride

2021

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Insecticide cartap hydrochloride (C) was fabricated as nanospheres by a two-step method of ionic gelification and polyelectrolyte complexation of alginate (ALG) and chitosan (CS) to undermine its adverse effects on environment. Nanospheres were characterized by field emission scanning electron microscope, Fourier transform infrared spectra and x-ray diffraction. The size of cartap hydrochloride entrapped chitosan alginate nanospheres (C-CS-ALG nps) was in range of 107.58–173.07 nm. Cartap hydrochloride nanospheres showed encapsulation efficiency of 76.19% and were stable for 30 d at ambient temperature. Release of cartap from nanospheres fitted best with first order linear kinetics followed by Hixson and Higuchi model suggesting super case II transport release. With the application of such control release nanoformulations, it is possible to reduce the frequency of field application of insecticide due to its slow release to the target organism, which is economical as well as environmentally safe.

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Section: Introductionmentioning

confidence: 99%