Four glycoproteins are expressed in the cat zona pellucida

Stetson, I.; Sánchez, Manuel A. Bueno; Moros, Carlos Lapresta; García-Vázquez, F. A.; Gimeno, Lourdes; Torrecillas, Alejandro; Aliaga, César; Bernardo-Pisa, M.V.; Ballesta, José Antonio Camacho; Izquierdo-Rico, M. J.

doi:10.1016/j.theriogenology.2014.12.019

Cited by 24 publications

(10 citation statements)

References 60 publications

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“…In mouse, it is constituted almost exclusively by three glycoproteins: ZP1, ZP2 and ZP3 (Gupta et al, ). Recently, a fourth glycoprotein (ZP4) was discovered in some species (Goudet, Mugnier, Callebaut, & Monget, ; Izquierdo‐Rico et al, ; Lefièvre et al, ; Stetson et al, ). Zona pellucida poses multiple roles during oogenesis, fertilization and pre‐implantation development (Florman & Ducibella, ; Yanagimachi, ).…”

Section: Introductionmentioning

confidence: 99%

Histochemistry of the zona pellucida of the ovary of a species with natural polyovulation: Lagostomus maximus (Rodentia, Hystricomorpha, Chinchillidae)

Acuña

Hoz

Díaz

et al. 2018

Reprod Domestic Animals

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This study reports the histochemistry and the distribution of glycoconjugates (GCs) in the zona pellucida (ZP) of preantral, secondary, tertiary, polyovulatory and atretic follicles of ovaries from non-pregnant (NPr) and pregnant (Pr) females of Lagostomus maximus. GCs were studied using histochemical and lectin histochemical methods. The viscacha ZP was positive to all the histochemical techniques. In addition, it was observed that the intensity of staining of the ZP was constant in the different follicular stages between both female groups. The lectin histochemical study revealed that ZP was positive for certain lectins (WGA, RCA-I and CON-A) and that the labelling did not vary between the different follicular stages, but between the two groups of females. By using both histochemical techniques, it was established that the GCs present in the ZP label the complexity of the area. These results allow us to increase our knowledge on the biology of the viscacha's ovary, particularly contributing to the study of polyovulation.

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Section: Introductionmentioning

confidence: 99%

Histochemistry of the zona pellucida of the ovary of a species with natural polyovulation: Lagostomus maximus (Rodentia, Hystricomorpha, Chinchillidae)

Acuña

Hoz

Díaz

et al. 2018

Reprod Domestic Animals

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“…The zona pellucida (ZP) is a glycoprotein layer that is synthesized and secreted by mammalian oocytes and surrounds it [ 37 ]. ZP in species like human [ 38 ], hamster [ 39 ], and cat [ 40 ] is formed by four glycoproteins (ZP1, ZP2, ZP3, and ZP4) and plays important roles in species-specific sperm-egg binding, preventing polyspermy, ZP-induced acrosome reaction, and protecting the embryo [ 38 ]. Zona pellucida binding protein (ZPBP) that is expressed in testis [ 28 ] is involved in male fertility, and defects in this gene are associated with abnormal sperm morphology [ 41 ].…”

Section: Discussionmentioning

confidence: 99%

Genome-Wide Identification and Analysis of Variants in Domestic and Wild Bactrian Camels Using Whole-Genome Sequencing Data

Hedayat-Evrigh

Khalkhali-Evrigh

Bakhtiarizadeh

2020

International Journal of Genomics

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The population size of Bactrian camels is smaller than dromedary, and they are distributed in cold and mountain regions and are also at the risk of extinction in some countries such as Iran. To identify and investigate the genome-wide variations, whole-genome sequencing of two Iranian Bactrian camels were performed with 37.4- and 42.6-fold coverage for the first time. Along with Iranian Bactrian camels, sequencing data from two Mongolian domestic and two wild Bactrian camels deposited in the NCBI were reanalyzed. The analysis eventuated to the identification of 4,908,998, 4,485,725, and 4,706,654 SNPs for Iranian, Mongolian domestic, and wild Bactrian camels, respectively. Also, INDEL variations ranged from 358,311 to 533,188 in all six camels. Results of variants annotation in all samples revealed that more than 88 percent of SNPs and INDELs were located in the intergenic and intronic regions. We found that 800,530 SNPs were common among all studied camels, containing 4,046 missense variants that affected 2,428 genes. Investigation of common genes among all camels containing the missense SNPs showed that there are 98 zinc finger and 4 fertility-related genes (ZP1, ZP2, ZP4, and ZPBP) in this set.

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“…The question that arises is whether the ZP from porcine oocytes (PZP) can be used in vaccine formulation meant for other mammalian species. Although the amount of individual ZP components differ, it is conserved among mammalian species; thus, PZP can be used in other species . ZP has two to four glycoprotein components: ZP1 serves as a cross‐linker between ZP2 and ZP3 dimers, ZP2 is the receptor for acrosome‐reacted sperm and prevents polyspermy, and ZP3 is the primary sperm receptor responsible for induction of acrosome reaction .…”

Section: Pzp Vaccinementioning

confidence: 99%

Immunocontraception for Animals: Current Status and Future Perspective

Naz

Saver

2015

American J Rep Immunol

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An alternative to surgical sterilization for fertility control of animals (wild, zoo, farm, and domestic) is needed to prevent problems related to overpopulation, including culling and relocation. A PubMed and Google Scholar database search was conducted using the keywords 'contraceptive vaccine animals,' 'immunocontraception animals,' 'non-surgical sterilization animals,' 'PZP vaccine,' and 'GnRH vaccine.' The searches from 1972 to 2015 yielded over 1500 publications. These articles were read, and 375 were selected for detailed analysis. Articles referenced in these publications were also thoroughly examined. PZP and GnRH contraceptive vaccines (CVs) have been extensively investigated for fertility control of wild, zoo, farm, and domestic animal populations. Both vaccines have shown tremendous success with PZP vaccines taking the lead. Novel technologies and targets are being developed to improve existing vaccines and generate second-generation CVs. Single-shot vaccines, which can be delivered remotely, will greatly advance the field of immunocontraception for animal use with potential human application.

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Four glycoproteins are expressed in the cat zona pellucida

Cited by 24 publications

References 60 publications

Histochemistry of the zona pellucida of the ovary of a species with natural polyovulation: Lagostomus maximus (Rodentia, Hystricomorpha, Chinchillidae)

Histochemistry of the zona pellucida of the ovary of a species with natural polyovulation: Lagostomus maximus (Rodentia, Hystricomorpha, Chinchillidae)

Genome-Wide Identification and Analysis of Variants in Domestic and Wild Bactrian Camels Using Whole-Genome Sequencing Data

Immunocontraception for Animals: Current Status and Future Perspective

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