Foveomacular Schisis in Juvenile X-Linked Retinoschisis: An Optical Coherence Tomography Study

Correlation Between Spectral-Domain OCT Findings and Visual Acuity in X-Linked Retinoschisis

“…10,11 However, a recent in vivo study that used SD-OCT showed that outer retinal abnormalities were also prevalent. [12][13][14]21 Our current study findings also support the results of that SD-OCT study, that is, by revealing that the main manifestation of schisis is at the INL (85%) and/or one of the outer retinal layers (85%). However, the most prevalent area of schisis or defect, when confined to the outer retina layer (including photoreceptor layers), was found in the OPL (60%) and COST line (75%).…”

“…In recent studies, schisis of the inner nuclear layer (INL) and outer nuclear layer (ONL) has also been observed in foveoschisis patients on optical coherence tomography (OCT). [12][13][14] However, Apushkin and associates 13 reported no correlation between visual acuity, foveal thickness, and cystic area in foveoschisis cases using time-domain OCT. 13 To our knowledge, the photoreceptor and choroidal features and their relationship with visual acuity have never been studied to date, although determining the origin and mechanism of poor vision in patients with XLRS is of the utmost importance.…”

Wide-Field Imaging of Nonexudative and Exudative Congenital X-Linked Retinoschisis

“…Optical coherence topography accurately demonstrates the characteristic intraretinal splitting of CXLRS. 2,10 Fluorescein angiography (FA) is a less preferred diagnostic tool, which usually shows characteristically normal findings with no vascular leakage, 2,5 but rare case reports have demonstrated pathologic FA findings including peripheral leakage in schisis cavities. 11,12 Vascular abnormalities noted on clinical examinations also include opacified vessels 11 and vascular sheathing.…”

Spectral Domain Optical Coherence Tomography Findings in Two Cases of X-Linked Juvenil Retinoschisis

“…As in our cases Yu et al reported a large series of XLRS and showed the foveomacular schisis seems to occur predominantly at the INL, occasionally at the ONL/OPL, and only rarely at the RNFL. 10 In conclusion, the schisis cavity can ocur in a number of different layers of neurosensory retina in patients with XLRS. SD-OCT allows enhanced visualization of retinal layers with high resolution imaging and is important for the diagnose and follow-up examinations of the disaese.…”