Fractalkin and cardiovascular disease

Alieva, Amina M.; Алмазова, И. И.; Pinchuk, T. V.; Резник, Е. В.; Rakhaev, A M; Никитин, И. Г.

doi:10.26442/20751753.2020.5.200186

Cited by 11 publications

(1 citation statement)

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“…Данные по биологическим маркёрам находят свое отражение и в современных клинических рекомендациях: для определения вероятности хронической сердечной недостаточности (ХСН) оценивают уровень мозгового натрийуретического пептида (BNP) и его N-концевого предшественника (NT-proBNP) в крови [3]. Однако для лучшего понимания нейрогуморальных и биомеханических аспектов при сердечно-сосудистых заболеваниях (ССЗ) необходима оценка дополнительных лабораторных биомаркёров [4][5][6]. Применение новых маркёров представляется перспективным, активно продолжается поиск «идеального» маркёра, который даст возможность понять многие механизмы ССЗ [1,7].…”

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Diagnostic and therapeutic aspects of neuregulin-1: A review

et al. 2023

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In recent decades, the prospect of using a biomarker strategy for early personalized diagnosis of cardiovascular pathology has been actively explored. The use of new markers seems promising, and the search for an ideal marker is actively ongoing, which will make it possible to understand many mechanisms of cardiovascular diseases. In recent years, the attention of scientists has been actively focused on studying the role of neuregulin-1 as a laboratory biological marker in cardiac pathology. Neuregulins belong to a superfamily of epidermal growth factors that are synthesized by the vascular endothelium in response to ischemia, adrenergic stimulation, and oxidative stress. A number of studies have shown the potentially important diagnostic and prognostic value of assessing neuregulin-1 as a biological marker. It is expected that further scientific and clinical studies will demonstrate the possibility of using this marker as an additional laboratory tool for diagnosing, risk stratifying and predicting cardiovascular events in patients with cardiovascular pathology. The therapeutic effect of recombinant neuregulin-1 on reducing morbidity and mortality in cardiac patients remains to be assessed in more detail.

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Diagnostic and therapeutic aspects of neuregulin-1: A review

et al. 2023

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Ghrelin as a promising biological marker in cardiovascular disease

Alieva

Pinchuk

Baykova

et al. 2022

Medical Journal of the Russian Federation

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This review highlights the current literature data on the peptide hormone ghrelin. Ghrelin is a 28-amino-acid peptide, which is the only known peptide hormone modified with fatty acids. Ghrelin is a natural receptor ligand that stimulates the secretion of growth hormones. In addition to the stomach, ghrelin is expressed in many organs such as the duodenum, jejunum, ileum, colon, lungs, heart, pancreas, kidneys, testicles, pituitary gland, and hypothalamus. The main biological functions of this peptide include growth hormone secretion, appetite stimulation, modulation of gastric acid secretion and motility, and an increase in endocrine and exocrine pancreatic secretions. Reference intervals for ghrelin are 8.50216.6 pg/mL. The studies analyzed have shown a strong relationship between ghrelin and cardiovascular system function. Studies have also described the cardioprotective effects of ghrelin. However, the molecular mechanisms underlying the effects of ghrelin on the heart are not fully understood. A further deeper understanding of the role of ghrelin and future clinical studies are necessary to determine the diagnostic, prognostic, and possibly therapeutic significance of this biomarker.

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Regulatory and legal regulation of medical care in the «cosmetology» profile in the Russian Federation

Kubanov

Kolsanova²,

Chertukhina

2022

Medical Journal of the Russian Federation

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The theoretical and methodological bases of the present study are scientific works, theoretical and methodological developments, current publications of domestic scientists, official normative legal acts, and description of their application in the practical activities of medical organizations providing cosmetology services. This study aimed to examine studies that have focused on the most pressing issues of the legal regulation of medical care to the population of the Russian Federation in the field of cosmetology, identify the main problems associated with the legal regulation of the industry, and summarize the proposals of medical organizations for its improvement. In the study, a survey study was conducted, which allowed researchers to identify and summarize the known literature on this topic, regardless of the publication type and study design. The study presents an analysis of the regulatory and legal regulations of the activities of employees and medical organizations providing services in the field of cosmetology. After completing the initial literature search, the authors analyzed, compared, summarized, and systematized the published information. The analysis made it possible to distribute the data obtained in several key areas of regulatory and legal regulation of domestic cosmetology, i.e., an excursion into history, regulatory and legal support for the activities of a cosmetology medical organization at the present stage, modern requirements for the activities of a doctor, in relation to medical cosmetology care. A content analysis was conducted on the use by medical organizations in the regions of the Russian Federation of the regulatory framework of the cosmetology industry, assessed its effect on the system of providing cosmetological care to the population at the present stage, identified several problems related to the legal regulation of the activities of medical cosmetology organizations and summarized proposals for its improvement.

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Fractalkin and cardiovascular disease

Cited by 11 publications

References 0 publications

Diagnostic and therapeutic aspects of neuregulin-1: A review

Diagnostic and therapeutic aspects of neuregulin-1: A review

Ghrelin as a promising biological marker in cardiovascular disease

Regulatory and legal regulation of medical care in the «cosmetology» profile in the Russian Federation

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