Free radical scavenging actions of virgin coconut oil

Abstract

Natural antioxidants are quite popular in beauty products. In further product development, natural antioxidants are needed from local products of the NTB community. This study aims to optimize the antioxidant activity of local products Virgin Coconut Oil (VCO) from Cocos nucifera L. grown in Lombok. This type of research is experimental laboratory research using the DPPH method. VCO was isolated by conventional methods, namely standing and layered filtration. Data were obtained from the results of the UV-Vis spectroscopy test. The results showed that the free radical inhibition of VCO was strong, with an IC50 value of 51.57 and an inhibition of 48% at a 5% VCO concentration. The absorbance of DPPH decreased with increasing reaction time. The decrease in absorbance from every 5 minutes indicates the antioxidant activity continues to a stationary point. A color change indicates the stationary point to yellow. The strong antioxidant activity of VCO is used as the basis for its use as an active ingredient in various cosmetic products. VCO is also believed to have a function as a natural moisturizer.

Determination of flavonoid levels of Macaranga gigantea and its activity as antioxidants

“…The purpose of scanning lambda is to obtain lambda DPPH with the maximum absorbance in a certain absorption area, where absorption light will be transmitted to a sample [16]. The Results obtained were 516 nm, and according to devotional research, that maximum lamda is 516 [7].…”

“…Test antioxidant quantitative with DPPH Test this started with the preparation of 0.4 mM DPPH in 25 mL methanol. Determination lamda max implemented with scanning Visible wavelength [7] Determination curve raw Scanning Wavelength _ is carried out at 400-500 nm. Quercetin concentrations were used _ to make curve raw is 5,10,20,40,80,160 ppm read at max lambda obtained from scanning long wave with operating time of 38 minutes [8] b.…”

Cytotoxicity activity of ethanol extract of mentangor stem skin (Calophyllum rufigemmatum) against breast cancer cells MCF-7 in vitro

“…The cytotoxic ethanol extract of the stem bark of mentangor (Calophyllum rufigemmatum) has the potential to be developed as a chemopreventive agent compared to the stem extract of Calophyllum rigidum Miq. which has an IC50 value of 1063.17 g/mL which is not toxic to breast cancer cells [12][13][14][15][16].…”

Antioxidants in the extract of balinese salak rind (Salacca amboinensis (Becc) Mogea) as an alternative substance to decrease blood sugar levels among Mus musculus L. with hyperglycemia

“…At the same time, inhibition of the glucokinase enzyme's thiol group disrupts Adenosine Triphosphate's formation in pancreatic beta cells, causing a decrease in insulin secretion. Based on the mechanism of action of alloxan, salak fruit extract containing saponins and flavonoids is able to provide antioxidant effects by donating electrons to the alloxan radicals formed so as to form more stable alloxan compounds and reduce the danger of alloxan in rat pancreas tissue [20][21][22]. It can be seen from the results of other studies, which showed the antioxidant content in doses of pare fruit extract [23], dragon fruit extract [24], and salak fruit extract combined with sappan wood extract [20].…”