Free Radical Scavenging Activities of b-Sitosterol Extracted from Abies yuanbaoshanensis

Abstract

Free radical scavengers or antioxidants are currently forged as the drug candidates to counter many diseases, such as drug-associated toxicity, inflammation, atherogenesis and aging in aerobic organisms [1][2][3] . Thus the significance of free radicals in the pathogenesis of various diseases has attracted considerable interest. Minor dietary compositions have been considerably deemed to combat the ill effects of free radicals. In addition, since that what may be learn from natural plants could overcome the toxicity problem of synthetic radical scavengers or antioxidants, so isolation of natural radical scavengers or antioxidants from natural plants has become a popular method.Abies yuanbaoshanensis, which distributed in Rongshui county in Guangxi Province of China, is a peculiar endangered precious plant. The pharmacological research has showed that it possess of wide biological activities 4 , including antitumor, antibacterial, antifungal, antiinflammatory and antitussive activities. Previous studies have indicated that various diseases such as antitumor, antibacterial and antifungal are characteristically associated with free radicals and ROS 5 . It is possible that some constitutes of Abies yuanbaoshanensis should get good free radical scavenging activities. So herein the extraction and radical-scavenging activities of Abies yuanbaoshanensis was studied.Abies yuanbaoshanensis were collected from Rongshui county of Guangxi Zhuang Autonomous Region in China, in July 2009 and verified by Prof. Zong-Ming Su. The air-dried needles and stems of Abies yuanbaoshanensis (10 Kg

Identification of Five New Triterpenoids from Ethylacetate Bark Extract of Holoptelea integrifolia (Roxb.) Planch by GC-MS

“…β-sitosterol (1) is known to possess anti-inflammatory and antipyretic [21], and antioxidant, and anti-diabetic potentials [22]. It has also been found to exhibit tyrosinase inhibitory [23] and radical scavenging properties [24]. It is a proven anticancer against certain cancers, human cancer cell lines (HL-60) [25].…”

Phytochemical and Pharmacological Studies on Four Indonesian Epiphytic Medicinal Plants: Drynaria rigidula, Hydnophytum formicarum, Usnea misaminensis, and Calymperes schmidtii

“…7 Compound 4 was also found in a 5-fold lower yield in our previous investigation of the rhizome D. rigidula (1.63 mg/g sample). 2 Phytochemical investigations into the hexane fraction from the initial methanol extract of H. formicarum produced 2 sterols stigmast-4-en-3-one 6 8 and β-sitosterol 3, 9 and the aniline derivative 4-aminophenyl acetate 7 (spectral data supplied in Supplemental material). This is the first report of these 3 compounds being isolated from this species.…”

“…(a Drynaria rigidula L, b Hynophytum formicarum jack, c Usnea misaminensis (Vain) Motyka and d Calymperes schmidtii broth.) Secondary metabolites isolated from 4 Indonesian epiphytic medicinal plants, Drynaria rigidula (1-3, 4, 5), Hynophytum formicarum(3, 6, 7), Usnea misaminensis(8,9), Calymperes schmidtii(10,11).…”