Freestanding Hyaluronic Acid/Silk-Based Self-healing Coating toward Tissue Repair with Antibacterial Surface

Xuan, Hongyun; Tang, Xiaoxuan; Zhu, Yue; Ling, Jue; Yang, Yumin

doi:10.1021/acsabm.9b01196

Cited by 32 publications

(18 citation statements)

References 51 publications

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“…Literature report development of hydrogel comprised of quaternaries chitosan and HA which is proved to be useful in wound healing. As well as other in reports researchers developed admantane modified HA and β‐Cyclodextrin modified silk fibroin coatings for wound healing applications 28 …”

Section: Functional Materials For Antimicrobial Applicationsmentioning

confidence: 92%

Natural and synthetic functional materials for broad spectrum applications in antimicrobials, antivirals and cosmetics

Shinde

Pawar

Vitore

et al. 2021

Polymers for Advanced Techs

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Antimicrobial resistance is the leading cause of burden on healthcare sector. There is scientific challenge of developing new functional material as a platform to prevent and treat viral and microbial infection and cosmetic utility. In material chemistry, there is progress in the development of functional material with advent of nanotechnology with aid of synthetic organic chemistry. The properties and application of material can be changed significantly by modification of the surface functional groups (namely, COOH, HO, NH2OH, SO4,), formation of composite with inorganic material and incorporation of active pharmaceutical agents. In antibacterial application functional material of copper, silver, gold, platinum, tin, iron, cobalt, ruthenium, zinc and pharmaceutical antimicrobial agents found utility in the treatment of bacterial and hospital acquired infection with different resistant strains of microorganisms. In antiviral application many functional materials have been shown to possess remarkable antiviral ability like quantum dots, gold and silver nanoparticles, nanoclusters, carbon dots, graphene oxide and silicon materials. The polymers and dendrimers functionalized with USFDA approved antiviral agent also has potential therapeutic outcomes. Despite their difference in antiviral mechanism and inhibition efficacy, these functional material structures have unique features as potential antiviral candidates. In cosmetic applications functional material based on mica, sericite, fullerene, charcoal, peptides, mineral, lipids, glucocorticoid, nanocellulose hybrid material are extensively used. In this review, we have highlighted early promise and prospects of functional material for cosmetics, antibacterial and antiviral applications, advantages and disadvantages, Patent scenario, current challenges for translation into commercial products.

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Section: Functional Materials For Antimicrobial Applicationsmentioning

confidence: 92%

Natural and synthetic functional materials for broad spectrum applications in antimicrobials, antivirals and cosmetics

Shinde

Pawar

Vitore

et al. 2021

Polymers for Advanced Techs

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show abstract

“…Importantly, the hemostatic activity of SF can further act as a cargo to release inflammatory factors to lead hemostasis to the next phase of the healing process ( Santin et al, 1999 ). However, lack of antibacterial activity limits the further application of SF on handling bleeding and dressing the wounds ( Xuan et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Light-Triggered Adhesive Silk-Based Film for Effective Photodynamic Antibacterial Therapy and Rapid Hemostasis

Huang

Zhou

et al. 2022

Front. Bioeng. Biotechnol.

Self Cite

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Successful control of massive hemorrhage in deep wounds with irregular shape and low elasticity still remains great challenges in the clinic. As the wound sites are usually at risk of bacterial infection, it is necessary to design an ideal hemostatic agent with rapid hemostasis and excellent antibacterial activity. In this study, we developed a light responsive hemostatic film for effective handling of liver bleeding with promising photodynamic therapy against S. aureus onnear infrared (NIR) irradiation. Based on silk fibroin, the film exhibited desirable biocompatibility and mechanical property as a hemostat tape. Significantly, the film tape achieved excellent tissue adhesion and hemostasis in vivo within 2 min of UV exposure, which would have a great potential as a multifunctional biomedical material in the field of tissue repair such as wound healing, bone repair, and nerve regeneration.

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“…Self-healing materials are widely used in military equipment, electronic products, [14][15][16][17][18][19] automobiles, airplanes, [20][21][22] building materials, [23] biological materials, [24] medical materials [25][26][27][28][29] and biomimetic technology, [30,31] The proportion of application is also increasing with each passing year (Figs. 1 a, b and c), for instance, self-healing materials can be used in dentistry in medical field.…”

Section: Introductionmentioning

confidence: 99%

Self-healing Materials: A Review of Recent Developments

Song¹,

Jiang²,

Li³

et al. 2021

ES Mater. Manuf.

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Self-healing polymer is a kind of functional polymer materials that can repair scratches, cracks and other mechanical damage, whose unique self-healing ability is of great significance for prolonging the life of materials. Eigen self-healing polymers have become the focus of current research due to their advantages of mild healing conditions and repeatable healing. In this paper, the preparation technology and properties of self-healing elastomers were reviewed, which provided guidance for the preparation of polymers with high repair efficiency and pointed out its future development trend. The self-healing polymer materials based on Diels-Alder reaction, metal bond, hydrogen bond, ionic bond, disulfide bond, etc., are mainly introduced, and their preparation process, healing mechanism and healing properties are reviewed. Although much progress has been made in self-healing elastomers based on different dynamic bonds, the development of materials with high repair efficiency remains a huge challenge. In this paper, various repair pathways of self-healing elastomers were reviewed, which provided guidance for the balance between repair and mechanical properties. The development of inherently self-healing polymers was also prospected.

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Freestanding Hyaluronic Acid/Silk-Based Self-healing Coating toward Tissue Repair with Antibacterial Surface

Cited by 32 publications

References 51 publications

Natural and synthetic functional materials for broad spectrum applications in antimicrobials, antivirals and cosmetics

Natural and synthetic functional materials for broad spectrum applications in antimicrobials, antivirals and cosmetics

Light-Triggered Adhesive Silk-Based Film for Effective Photodynamic Antibacterial Therapy and Rapid Hemostasis

Self-healing Materials: A Review of Recent Developments

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