Frequency-dependent selection, metrical characters and molecular evolution

Clarke, Bryan; Shelton, P. R.; Mani, G.S.

doi:10.1098/rstb.1988.0070

Cited by 30 publications

(5 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The conditions to maintain genetic polymorphisms within populations are fairly restrictive, relying on some degree or combination of frequency-dependent selection, overdominance, and overlapping generations (Felsenstein 1976). Besides G × E interactions, frequency-dependent selection represents a powerful, alternative mechanism to maintain polymorphisms in natural populations (Ayala and Campbell 1974;Clarke et al 1988). For example, color polymorphisms in male guppies are maintained by negative frequency-dependent selection mediated by female mate choice (Hughes et al 2013) and a survival advantage of rare males (Olendorf et al 2006).…”

Section: Limitations and Alternativesmentioning

confidence: 99%

Environmental heterogeneity generates opposite gene-by-environment interactions for two fitness-related traits within a population

et al. 2015

View full text Add to dashboard Cite

Theory predicts that environmental heterogeneity offers a potential solution to the maintenance of genetic variation within populations, but empirical evidence remains sparse. The live-bearing fish Xiphophorus variatus exhibits polymorphism at a single locus, with different alleles resulting in up to five distinct melanistic "tailspot" patterns within populations. We investigated the effects of heterogeneity in two ubiquitous environmental variables (temperature and food availability) on two fitness-related traits (upper thermal limits and body condition) in two different tailspot types (wild-type and upper cut crescent). We found gene-by-environment (G × E) interactions between tailspot type and food level affecting upper thermal limits (UTL), as well as between tailspot type and thermal environment affecting body condition. Exploring mechanistic bases underlying these G × E patterns, we found no differences between tailspot types in hsp70 gene expression despite significant overall increases in expression under both thermal and food stress. Similarly, there was no difference in routine metabolic rates between the tailspot types. The reversal of relative performance of the two tailspot types under different environmental conditions revealed a mechanism by which environmental heterogeneity can balance polymorphism within populations through selection on different fitness-related traits.

show abstract

Section: Limitations and Alternativesmentioning

confidence: 99%

Environmental heterogeneity generates opposite gene-by-environment interactions for two fitness-related traits within a population

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Models of balancing selectionincluding negative frequency-dependent selection, spatial or temporal habitat heterogeneity, and heterozygote advantage-provide theoretical frameworks describing the processes that can account for persistent polymorphisms within populations. A core tenet of each balancing selection model is that the selective value of an allele-whether it is beneficial or detrimental-is dependent on the environmental context (Dobzhansky, 1982;Clarke et al, 1988). That is, alleles are advantageous and deleterious in different circumstances.…”

Section: Introductionmentioning

confidence: 99%

Negative Frequency-Dependent Selection Is Frequently Confounding

Brisson

2018

Front. Ecol. Evol.

View full text Add to dashboard Cite

Persistent genetic variation within populations presents an evolutionary problem, as natural selection and genetic drift tend to erode genetic diversity. Models of balancing selection were developed to account for the maintenance of genetic variation observed in natural populations. Negative frequency-dependent selection is a powerful type of balancing selection that maintains many natural polymorphisms, but it is also commonly misinterpreted. This review aims to clarify the processes underlying negative frequency-dependent selection, describe classes of polymorphisms that can and cannot result from these processes, and discuss the empirical data needed to accurately identify processes that generate or maintain diversity in nature. Finally, the importance of accurately describing the processes affecting genetic diversity within populations as it relates to research progress is considered.

show abstract

“…Models of balancing selection -including negative frequency-dependent selection, spatial or temporal habitat heterogeneity, and heterozygote advantage -provide theoretical frameworks of the processes that can account for persistent polymorphisms within populations. A core tenet of each balancing selection model is that the selective value of an allele -whether it is beneficial or detrimentalis dependent on the environmental context [12,13]. That is, alleles are advantageous and deleterious in different ecological contexts.…”

Section: Introductionmentioning

confidence: 99%

Negative frequency-dependent selection is frequently confounding

Brisson

2017

Preprint

View full text Add to dashboard Cite

The existence of persistent genetic variation within natural populations presents an evolutionary problem as natural selection and genetic drift tend to erode genetic diversity. Models of balancing selection were developed to account for the high and sometimes extreme levels of polymorphism found in many natural populations. Negative frequency-dependent selection may be the most powerful selective force maintaining balanced natural polymorphisms but it is also commonly misinterpreted. The aim of this review is to clarify the processes underlying negative frequencydependent selection, describe classes of natural polymorphisms that can and cannot result from these processes, and discuss observational and experimental data that can aid in accurately identifying the processes that generated or are maintain diversity in nature. Finally, I consider the importance of accurately describing the processes affecting genetic diversity within populations as it relates to research progress.

show abstract

Frequency-dependent selection, metrical characters and molecular evolution

Cited by 30 publications

References 17 publications

Environmental heterogeneity generates opposite gene-by-environment interactions for two fitness-related traits within a population

Environmental heterogeneity generates opposite gene-by-environment interactions for two fitness-related traits within a population

Negative Frequency-Dependent Selection Is Frequently Confounding

Negative frequency-dependent selection is frequently confounding

Contact Info

Product

Resources

About