Frequency of Abh Secretors and Non Secretors in Pakistani Population

Saboor, Muhammad; Ullah, Aman; Qamar, Khansa; Mir, Awal; Moinuddin, Mohammed

doi:10.12669/pjms.301.4194

Cited by 17 publications

(18 citation statements)

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“…Emeribe et al [11] and Jaff [12] reported similar findings in their studies. Saboor M et al, [13] conducted a study to evaluate the ABH blood group among 101 healthy adult students and concluded that the frequency was highest in blood group B which was in accordance with our study. It is also seen that out of 50 subjects, 48 of them showed the secretor level similar to the study conducted by Pereira M et al, [14] Kimura A et al, [15] Parekh P et al, [16] and Pawan Motghare et al [4] .…”

Section: Discussionsupporting

confidence: 91%

Saliva in identification of ABO Blood Grouping Rhesus Factor

Harshada R

2020

Indian Journal of Forensic Medicine & Toxicology

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Aim: To assess the efficacy and reliability of saliva in identification of ABO blood grouping. Materials and Method:The study was conducted in the outpatient department of Oral Medicine and Radiology. The serum and saliva of 50 participants were collected and the blood group of the individual from serum was identified by the slide agglutination method and from saliva by the absoption elution method.Results: Data obtained were subjected to statistical analysis using Paerson's chi square test and it showed high significance (P = <0.001). Conclusion:The outcome of the present study showed that saliva can be used as an aid in forensics for identification of ABO blood grouping of an individual.

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Section: Discussionsupporting

confidence: 91%

Saliva in identification of ABO Blood Grouping Rhesus Factor

Harshada R

2020

Indian Journal of Forensic Medicine & Toxicology

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“…Lewis blood type is genetically determined by the Lewis gene ( fucosyltransferase 3 ), which encodes for α1,3/4 fucosyltransferase, and the Secretor gene ( fucosyltransferase 2 ), which encodes for α1,2 fucosyltransferase [ 8 ]. Worldwide it is estimated that around 20% of individuals have inactive secretor genes (non-secretor) though geographic and racial differences have been reported [ 9 , 10 ]. The breast milk of non-secretor mothers lack α1,2 fucosyl-oligosaccharides [ 7 , 11 ] and contain around half of the amount of neutral oligosaccharides compared to the breast milk of mothers with active Secretor genes [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Mothers Secretor Status Affects Development of Childrens Microbiota Composition and Function: A Pilot Study

et al. 2016

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BackgroundOne mechanism by which early life environment may influence long term health is through modulation of the gut microbiota. It is widely accepted that the optimal source of nutrition in early life is breast milk, with Human Milk Oligosaccharides (HMOs) thought to play an important role in nourishing the developing microbiota. However, mothers with inactive secretor genes have altered HMO composition and quantities in their breast milk. In this pilot study we examine the influence of secretor status and breast-feeding on microbiota composition at 2 to 3 years of age.Methods37 children and 17 eligible mothers were recruited. Secretor status was determined from blood and saliva samples using hemagglutination inhibition technique and faecal microbiota composition was examined by 16S rRNA gene sequencing.ResultsSecretor status was determined for 28 eligible children with 20 being secretors (S, 71.4%). Eleven of the 17 mothers were secretors (S, 64.7%). Unweighted UniFrac distances were significantly associated with child secretor status (R2 = 0.069, p = 0.030) and with mother secretor status in children exclusively breastfed for at least 4 months (R2 = 0.167, p = 0.028), suggesting an influence on the presence/absence of microbes, with Prevotella not detected in samples from secretor children and children of secretor mothers. In children who were exclusively breast-fed for at least 4 months of life the abundance of the known HMO consumers Bifidobacterium were increased in the children of secretor mothers compared to non-secretor mothers. The relative abundance of an OTU related to Bacteroides plebeius, a bacterium noted for its capacity to utilise sulphated polysaccharides for growth, was decreased in these children.ConclusionsChild and mothers’ secretor status have an impact on childrens’ microbiota composition at 2 to 3 years of age.

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“…Out of which 75% were of group O and 61.5% in group A [Table/ Fig-3]. These two studies compared Absorption-Inhibition and Absorption-Elution Methods in the detection of ABO (H) antigens in vaginal samples, submitted in sexual offense cases and stated that the Absorption-inhibition is a well-established method for the identification of ABO (H) antigens [14].…”

Section: Discussionmentioning

confidence: 99%

“…In the most recent study done in 2014 by Saboor M et al, to evaluate the ABH blood group among 101 healthy adult students (76 male, 25 female ranging in age from 15 to 40 years), to know the secretors and non-secretors in people of Karachi, Pakistan using haemagglutination inhibition method of saliva [14]. They concluded that frequency of ABH secretor is high (64.4%).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Secretor Status of ABO Blood Group Antigens in Saliva among Southern Rajasthan Population Using Absorption Inhibition Method

Metgud

Khajuria²,

Mamta

et al. 2016

JCDR

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Introduction:The ABO blood group system was the significant element for forensic serological examination of blood and body fluids in the past before the wide adaptation of DNA typing. A significant proportion of individuals (80%) are secretors, meaning that antigens present in the blood are also found in other body fluids such as saliva. Absorption inhibition is one such method that works by reducing strength of an antiserum based on type and amount of antigen present in the stains. Aim:To check the efficacy of identifying the blood group antigens in saliva and to know the secretor status using absorption inhibition method among southern Rajasthan population.

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Frequency of Abh Secretors and Non Secretors in Pakistani Population

Cited by 17 publications

References 1 publication

Saliva in identification of ABO Blood Grouping Rhesus Factor

Saliva in identification of ABO Blood Grouping Rhesus Factor

Mothers Secretor Status Affects Development of Childrens Microbiota Composition and Function: A Pilot Study

Evaluation of the Secretor Status of ABO Blood Group Antigens in Saliva among Southern Rajasthan Population Using Absorption Inhibition Method

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