Frequency of incidental fatty liver on ultrasound and its association with diabetes mellitus and hypertension

Abstract

Objective:To see the frequency of incidental fatty liver on ultrasound and its association with diabetes mellitus and hypertension.Methods:A cross sectional study was conducted from January 2016 to June 2016 in the department of Surgery and Radiology at Hamdard University Hospital. Patients of both genders and all ages were selected by non purposive convenience sampling. Critically ill, trauma cases and all those patients who had a history of chronic liver disease, alcohol intake and expected pregnancy were excluded. Blood pressure and random blood sugar were recorded.Results:Six hundred patients were included in the study with mean age of 44.65±18.8 years. 240 patients (40%) had incidental finding of fatty liver on ultrasound. Out of 240 with fatty liver patients 117 were males (48.8%) and 123 were females (51.3%). Total 141 patients were diagnosed with hypertension, out of which 81(57.44%, p< 0.001) had fatty liver on ultrasound. Diabetes mellitus was diagnosed in 84 patients, in which 57 patients (67.8%, p<0.001) had fatty liver.Conclusion:Fatty liver is a frequently found incidental finding on ultrasound. There is a significant association of fatty liver with diabetes mellitus and hypertension.

Evaluation of the Role of Hyaluronic Acid as A potential Biomarker for Diagnosis of Non-Alcoholic Fatty Liver Disease

“…We also found in our study that there was a highly significant statistical difference between study groups as regard random blood sugar (RBS) (p<0.001). This result agrees with the study of Zubair et al (13) who reported that diabetic patients are at strong risk for both NAFLD and NASH and there is a significant association of fatty liver with DM. Another study explained that the close association between NAFLD and type 2 DM lies in that they have a common pathogenesis, which is insulin resistance.…”

The development of the Metabolic-associated Fatty Liver Disease during pharmacotherapy of mental disorders - a review

“…Less often it can be associated with noticeable fatigue or discomfort in the right upper quadrant of the abdomen. It can be diagnosed unexpectedly, during an ultrasound examination (USG) performed for another reason or based on elevated serum of alanine transaminase (ALT) and aspartate aminotransferase (AST) liver enzymes [8,12].…”

Dietary sodium intake in relation to non-alcoholic fatty liver disease risk: a case-control study

“…Other risk factors include hypertension (HTN) (Li et al , 2017) and cardiovascular disease (CVD) (Ma et al , 2017). The development of NAFLD is caused by multiple factors such as dietary habits and sedentary lifestyle (Zubair et al , 2018). NAFLD includes different degrees of hepatic disorders from a simple steatosis, up to cirrhosis and hepatocellular carcinoma (Zubair et al , 2018; Mullish et al , 2018).…”

“…The development of NAFLD is caused by multiple factors such as dietary habits and sedentary lifestyle (Zubair et al , 2018). NAFLD includes different degrees of hepatic disorders from a simple steatosis, up to cirrhosis and hepatocellular carcinoma (Zubair et al , 2018; Mullish et al , 2018). In addition to hepatic complications, NAFLD has some extra hepatic complications such as metabolic syndrome, T2DM, HTN (Zubair et al , 2018) and other metabolic disorders such as dyslipidemia and CVD (Huh et al , 2015).…”

“…NAFLD includes different degrees of hepatic disorders from a simple steatosis, up to cirrhosis and hepatocellular carcinoma (Zubair et al , 2018; Mullish et al , 2018). In addition to hepatic complications, NAFLD has some extra hepatic complications such as metabolic syndrome, T2DM, HTN (Zubair et al , 2018) and other metabolic disorders such as dyslipidemia and CVD (Huh et al , 2015). Regarding bidirectional association between NAFLD and other metabolic disorders, it is important to identify the modifiable risk factors of NAFLD and prevent the onset and progression of NAFLD and its consequences.…”