From salt to hypertension, what is missed?

Ma, Zhiyi; Hummel, Scott L.; Sun, Ning; Chen, Yuanyuan

doi:10.1111/jch.14402

Cited by 6 publications

(3 citation statements)

References 99 publications

(212 reference statements)

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“…Excess dietary salt consumption was also an essential risk factor for the development and progression of cardiovascular disease. Educational degree is an important socioeconomic factor, there was developing proof that in addition to these widespread risk factors, income level and social status were factors that may associated be with BP control ( 39 ). As a result, stopping unhealthy lifestyles may additionally make a contribution to patients' health.…”

Section: Discussionmentioning

confidence: 99%

Association Between ABCA1 Gene Polymorphisms and the Risk of Hypertension in the Chinese Han Population

Ren

Tong

Chen

et al. 2022

Front. Public Health

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BackgroundHypertension is rising as a major public health burden around the world. This study explored the association between single-nucleotide polymorphisms (SNPs) in the adenosine triphosphate (ATP)-Binding Cassette Subfamily A1 (ABCA1) gene and hypertension among Chinese Han adults.MethodA total of 2,296 Han Chinese in southeast China were recruited for this study. We collected medical reports, lifestyle details, and blood samples from individuals. The polymerase chain reaction-ligase detection reaction (PCR-LDR) method was used to detect the genotypes of these SNPs in the ABCA1 gene.ResultsAfter adjusting some covariates, the additive and recessive models of the rs2472510 and rs2515614 were significantly associated with hypertension. The haplotypes TCTA (rs2297406-rs2472433-rs2472510-rs2515614) were associated with high SBP, and the haplotypes CCTA, TCTA, and TTTA were associated with high diastolic blood pressure (DBP).ConclusionThe results of the relationship between the polymorphisms of rs2297406, rs2472433, rs2472510, and rs2515614 in ABCA1 and hypertension in southeastern China would provide a theoretical basis for genetic screening and disease prevention.

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Section: Discussionmentioning

confidence: 99%

Association Between ABCA1 Gene Polymorphisms and the Risk of Hypertension in the Chinese Han Population

Ren

Tong

Chen

et al. 2022

Front. Public Health

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“…[7][8][9] High salt intake was defined as salt intake ≥ 6 g/d. [10] Insufficient physical activity was defined as less than 150 minutes of moderate-intensity aerobic exercise per week or less than 75 minutes of high-intensity aerobic exercise per week in adults. [11] Good sleep was defined as sleeping for 6 to 8 hours a day, and poor sleep was defined as sleeping less than 6 hours or more than 8 hours a day.…”

Section: Diagnostic Criteria and Relevant Definitionsmentioning

confidence: 99%

Epidemiological survey of hypertension among middle-aged and elderly adults in Anhui Province

Zhai,

Cui,

et al. 2023

Medicine

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To understand and analyze the prevalence and treatment of hypertension among residents aged 45 years and older in northern and southern Anhui Province to provide an opportunity to improve awareness, taking into account and standardizing hypertension management. Using a stratified cluster random sampling method, Anhui Province was divided into northern and southern Anhui regions using the Yangtze River as the boundary. The prevalence rate, awareness rate, treatment rate, control rate, related risk factors and complications of hypertension in the community population aged ≥ 45 years in Anhui Province were investigated using a questionnaire survey and a physical examination. The chi-square test was used to analyze the regional differences in hypertension prevalence, awareness, treatment and control rates. Weighted logistic regression was used to analyze the risk factors for hypertension. A total of 1331 residents aged ≥ 45 years were included. The results showed that the overall prevalence of hypertension in the Anhui Province population aged ≥ 45 years was 47.48% (50.73% in northern Anhui and 43.21% in southern Anhui), and the prevalence of hypertension in northern Anhui was higher than that in southern Anhui. The survey showed that the overall hypertension awareness rate in Anhui Province was 59.67%, the hypertension treatment rate was 44.46%, and the hypertension control rate was 30.70%. The differences between the 2 regions was statistically significant. The hypertension awareness, treatment and control rates in southern Anhui were higher than those in northern Anhui (P < .05). The risk factors for hypertension were older age, rural residence, male, obesity, low education level, high salt diet, smoking, excessive drinking, poor sleep, insufficient exercise, a family history of hypertension, a history of diabetes, and a history of hyperlipidemia. The most common complication of hypertension in middle-aged and elderly people in Anhui Province was cerebrovascular disease, followed by cardiovascular disease. Calcium channel blockers were the most commonly used antihypertensive drugs in middle-aged and elderly people in Anhui Province, followed by angiotensin converting enzyme inhibitor or angiotensin receptor blocker receptor antagonists.

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“…Although the reduction in sodium consumption along with an increase in potassium intake are well‐known recommendations in the management of hypertension (Castro et al, 2015; Lari et al, 2021; Leung et al, 2016; Ma et al, 2021; Mahmood et al, 2019), functional foods have gained interest in lowering BP due to the food matrix effect, which includes not only macronutrients, micronutrients, and fiber, but also non‐essential elements such as flavonoids (Borghi & Cicero, 2017; Matsutomo, 2020; Santos et al, 2020. 2021; Santos & RCO, 2018; P. Wang et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

The effects of blueberry and cranberry supplementation on blood pressure in patients with cardiovascular diseases: A systematic review and meta‐analysis of randomized clinical trials

Delpino,

dos Santos,

Flores

et al. 2023

Phytotherapy Research

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Blueberries and cranberries are berry fruits with the highest number of randomized clinical trials (RCTs) focusing on blood pressure (BP). This systematic review and meta‐analysis of RCTs analyzed the effects of blueberry and cranberry supplementation alone and in concert with systolic BP (SBP) and diastolic BP (DBP) in patients with cardiometabolic diseases. The searches were performed until August 2023 in the following databases: PubMed, Scopus, Web of Science, Cochrane, and Embase. Studies that examined the effects of blueberry or cranberry intake/supplementation were included. The risk of bias was evaluated using the Rob 2 scale. A meta‐analysis was performed to estimate the effects of blueberry and cranberry supplementation on BP levels in patients with cardiometabolic diseases. A total of 17 articles were included, from which two found significant results from blueberry and/or cranberry supplementation in reducing BP. Pooled results revealed statistically non‐significant reductions of −0.81 mm Hg for SBP (95% confidence interval [CI]: −2.26, 0.63; I2 = 0%) and −0.15 mm Hg for DBP (95% CI: −1.36, 1.05; I2 = 27%). Blueberry and/or cranberry supplementation had neutral effects on SBP and DBP in patients with cardiometabolic diseases, regardless of duration or age. Further high‐quality studies are needed to firmly establish clinical efficacy.

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From salt to hypertension, what is missed?

Cited by 6 publications

References 99 publications

Association Between ABCA1 Gene Polymorphisms and the Risk of Hypertension in the Chinese Han Population

Association Between ABCA1 Gene Polymorphisms and the Risk of Hypertension in the Chinese Han Population

Epidemiological survey of hypertension among middle-aged and elderly adults in Anhui Province

The effects of blueberry and cranberry supplementation on blood pressure in patients with cardiovascular diseases: A systematic review and meta‐analysis of randomized clinical trials

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