Functional state of palatine tonsils in children with diabetes type 1

Лайко, Андрей Афанасиевич; Гавриленко, Юрий Владимирович; Волгина, Ирина Евгеньевна

doi:10.15587/2313-8416.2016.59330

Cited by 3 publications

(2 citation statements)

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“…Наиболее часто при ХТ развивается патология почек, сердечно-сосудистой системы, щитовидной железы, частота ревматических осложнений составляет 3% [3,4]. Известно, что у пациентов с сахарным диабетом ХТ способствует прогрессированию нарушений углеводного обмена за счет изменения функции поджелудочной железы и гиперсекреции протеолитического фермента [5,6]. В то же время вследствие воздействия патологических импульсов на гипоталамогипофизарную систему возможно развитие гипертиреоза и ряда кожных заболеваний, вегетососудистой и нейроэндокринной дисфункции [7][8][9][10].…”

Section: Introductionunclassified

Management peculiarities of patients with chronic tonsillitis in comorbid conditions

Vladimirova,

Fatenkov,

Sokolova

et al. 2023

Medicinskij sovet

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Introduction. Chronic tonsillitis (CT) remains an urgent challenge in outpatient practice of not only otorhinolaryngologists, but also multi-discipline specialists – primary care physicians and general practitioners.Aim. To study the effectiveness of Tonsilgon® N at the outpatient care stage in CT patients with and without comorbidities. Materials and methods. 62 patients (30 to 56 years of age, average age 43.8 ± 13.2 years) with compensated CT were treated. The patients were divided into two groups: Group 1 (n = 30) included patients with compensated CT, Group 2 (n = 32) – patients with compensated CT and comorbidities: diabetes mellitus was detected in 40.6%, autoimmune thyroiditis in 43.7%, psoriasis in 15.7% of examined patients.Results and discussion. Evaluation of treatment outcomes using a 10-point visual analogue scale showed a significant (p < 0.05) health improvement in patients of both groups who received Tonsilgon® N. The examination showed a 1.8-fold decrease in the severity of the local symptom of CT – hyperemia and a roll-like thickening of the edges of the pillars of the fauces in patients of both groups by the 7th day of treatment. The trends of changes were characterized by uniformity, amounting to 0.09 ± 0.02 scores in Group 1 and 0.1 ± 0.02 scores in Group 2 (p < 0.05) by the 14th day of treatment. In CT patients without comorbidities, exacerbations that developed within 3 months were only observed in 6.6% of patients, and occurred in a mild form, which made it possible to abandon the use of antibacterials for systemic use; in Group 2 with comorbidities, they were more common and developed in 12.5% of patients.Conclusion. The high rate of successful treatment outcomes confirms the safety of the drug as an effective agent to relieve the severity of CT symptoms.

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Section: Introductionunclassified

Management peculiarities of patients with chronic tonsillitis in comorbid conditions

Vladimirova,

Fatenkov,

Sokolova

et al. 2023

Medicinskij sovet

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“…ХТ, сочетающийся с сахарным диабетом, может способствовать прогрессированию нарушения углеводного обмена за счет влияния на функцию поджелудочной железы и гиперсекреции протеолитического фермента. При этом наблюдается повышение гликемического профиля, усиливаются гипергликемия и глюкозурия [19]. В свою очередь декомпенсация углеводного обмена негативно сказывается на течении инфекции небных миндалин [20,21].…”

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Tonsillitis and tonsillogenic conditions

Karpishchenko

Lavrenova

Baranskaya

2016

Vestn. otorinolaringol.

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The objective of the present study was to analyze and summarize the literature publications concerning tonsillitis and related (tonsillogenic) pathological conditions. The retrospective analysis of these materials made it possible to collect and summarize information about the influence of palatine tonsillar pathology (chronic tonsillitis) on the function of various organs and their systems. It has been shown that pathogenesis of a great variety of disease is underlain by pathology of palatine tonsils. Also, the possibility to stabilize the pathological processes in certain organs and systems by the conservative and/or surgical treatment of chronic tonsillitis has been demonstrated. It is concluded that the patients presenting with chronic tonsillitis make up a group of risk of development of many serious somatic diseases and require enhanced attention not only of otorhinolaryngologists but also specialists representing other medical disciplines. The multidisciplinary approach to the management of such patients is the sole way to reduce the frequency ofgeneral complications in the patients with chronic tonsillitis.

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Clinical and Laboratory Peculiarities of Children’s State With Chronic Tonsilitis on Type 1 Diabetes

et al. 2020

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The aim: Improvement of early diagnostics quality and efficiency of chronic pharyngeal diseases (CPD) treatment in children with DM-1 by studying the clinical and laboratory features of the disease course and complex therapy administration. Materials and methods: A comprehensive examination of 707 children with diabetes mellitus-1, aged 3 to 18, was conducted, which determined clinical and laboratory features of their state in the presence and absence of chronic tonsillitis (CT). Results: Using microbiological and cytological examination of the palatine tonsils (PT) crypts, the leading role of microbial associations in the pathogenesis of HT in the formation of immune inflammation was determined, their influence on the local immunity indices was defined. Significant disturbances of the microcirculatory bed (MCB) in the presence of HT in children with DM-1, direct correlation between CPD and the presence of vascular glomeruli, changes in the retinal capillary structure (r = 0,332; p <0,05) according to biomicroscopy bulbar conjunctiva (BMBC) data were determined. The study of psycho-emotional state in children with CT and DM-1 was conducted, along with applied psycho-corrective program, which significantly reduces the manifestations of aggressiveness, aggression, and frustration reactions in them. Сonclusions: A non-invasive complex of the study of PT state on changes of local immunity indices, microbiocenosis and cytological data for correction of CPD course was developed, which allows to obtain faster compensation of CT and contributes to patients’ quality of life improvment.

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Functional state of palatine tonsils in children with diabetes type 1

Cited by 3 publications

References 1 publication

Management peculiarities of patients with chronic tonsillitis in comorbid conditions

Management peculiarities of patients with chronic tonsillitis in comorbid conditions

Tonsillitis and tonsillogenic conditions

Clinical and Laboratory Peculiarities of Children’s State With Chronic Tonsilitis on Type 1 Diabetes

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