2008
DOI: 10.2741/2883
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Fundamental principles and applications of microfluidic systems

Abstract: Microelectromechanical systems (MEMS) technology has provided the platform for the miniaturization of analytical devices for biological applications. Beside the fabrication technology, the study and understanding of flow characteristics of fluid in micrometer or even nanometer scale is vital for the successful implementation of such miniaturized systems. Microfluidics is currently under the spotlight for medical diagnostics and many other bio-analysis as its physical size manifested numerous advantages over la… Show more

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Cited by 73 publications
(41 citation statements)
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“…antibodies), and the quantity of the sample volumes are often limited [3]. Another appealing aspect of such devices as lab-on-a-chip (LOC) is that they are able to carry out separation and detection with high resolution and sensitivity [4,5]. Thirdly, the small size makes it a portable analytical device without the need of access to a proper laboratory.…”
Section: Introductionmentioning
confidence: 99%
“…antibodies), and the quantity of the sample volumes are often limited [3]. Another appealing aspect of such devices as lab-on-a-chip (LOC) is that they are able to carry out separation and detection with high resolution and sensitivity [4,5]. Thirdly, the small size makes it a portable analytical device without the need of access to a proper laboratory.…”
Section: Introductionmentioning
confidence: 99%
“…Moreover, microfluidics is a promising technology in cell-based screening industry as their benefits include reduced reagent consumption and thus lower cost [13].…”
Section: Introductionmentioning
confidence: 99%
“…Finally, the potential and challenges about integrated PCR chips are discussed. As a supplement to this review, readers are referred to other reviews about microfluidic technology [11][12][13][14].…”
Section: Introductionmentioning
confidence: 99%