2018
DOI: 10.3389/fmicb.2018.00583
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Fungi-Induced Upper and Lower Respiratory Tract Allergic Diseases: One Entity

Abstract: Introduction: Aspergillus can cause different allergic diseases including allergic bronchopulmonary aspergillosis (ABPA) and allergic fungal rhinosinusitis (AFRS). ABPA is allergic pulmonary disease against Aspergillus antigens. AFRS is a type of chronic rhinosinusitis (CRS) presented as hypersensitivity reactions to the fungal presence in sinuses. The aim of the present study was to clarify if ABPA and AFRS could be considered as a common disease entity.Methodology: The prospective cohort study included 75 pa… Show more

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Cited by 30 publications
(16 citation statements)
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“…Our data showed no bacterial growths in 5.3% of sputum and 14.61% of bronchial wash specimens (Table I). The undetectable bacterial growth might not reflect the absence of LRIs, as some LRIs cases are due to fungal or viral infections (Troeger, et al, 2019;Barac, et al, 2018). However, this suggestion was not conformed since the focus of this study was only on bacteria.…”
Section: Discussionmentioning
confidence: 83%
“…Our data showed no bacterial growths in 5.3% of sputum and 14.61% of bronchial wash specimens (Table I). The undetectable bacterial growth might not reflect the absence of LRIs, as some LRIs cases are due to fungal or viral infections (Troeger, et al, 2019;Barac, et al, 2018). However, this suggestion was not conformed since the focus of this study was only on bacteria.…”
Section: Discussionmentioning
confidence: 83%
“…Aspergillus species primarily affects the lungs causing upper and lower airway disorders. [12,13] Its spores are ubiquitous and present almost everywhere in the human environment, outdoor and indoor. [14] Among Aspergillus species, A. fumigatus was most commonly isolated followed by A. flavus in our study, this finding is similar to Farooq S et al related to mycological profile of LRTI.…”
Section: Discussionmentioning
confidence: 99%
“…In one study of 95 patients with ABPA, diagnoses of definite and probable AFRS were reached in 7 (7%) and 13 (14%) patients, respectively [7], although their concurrence might be more frequent based on the “one airway, one disease” hypothesis. Another study reported that AFRS was confirmed in 80% with patients of ABPA [8]. The difference in the percentage of patients with concomitant ABPA and AFRS between the two studies might be partially explained by the differences in the diagnostic criteria for ABPA and AFRS.…”
Section: Discussionmentioning
confidence: 99%