Furans and their Benzo Derivatives: Applications

Very Efficient and Rapid Catalyst-free One-pot Three Component Synthesis of 2,5-Dihydro-5-imino-2-methylfuran-3,4-dicarboxylate Derivatives Under Ultrasound Irradiation

“…[6][7][8] Many naturally occurring furans show interesting biological activities, such as cytotoxic and antitumor properties 9 as well as antispasmodic 10 antimicrobial 11,12 and several other potentially useful activities. 13 Furthermore, 2,5-disubstituted furan-3,4-dicarboxylates are very important starting materials in the synthesis of natural products containing tetrahydrofuran rings.…”

Synthesis of 2-(alkylamino)-5-{alkyl[(2-oxo-2H-chromen-3-yl)carbonyl]amino}-3,4-furandicarboxylates using a multi-component reaction in water

“…2e5 Many naturally occurring furans have exhibited considerable biological activities, such as antitumor and cytotoxic properties, 6 as well as antimicrobial, 7 antispasmodic, 8 and several other potentially useful activities. 9,10 In addition, furans are also present in commercially important products, such as agrochemical bioregulators, essential oils, cosmetics, dyes, photosensitizers, flavoring and fragrance compounds. 10,11 This broad range of applications has made the development of new and efficient furan synthesis very valuable.…”

Reaction of Substituted Furan-2-carboxaldehydes and Furo[b]pyrrole Type Aldehydes with Hippuric Acid

“…Substituted furans are ubiquitous structural units in natural products and pharmaceuticals [1] and have been widely used as synthetic intermediates [2,3].…”