Furosemide vor Test for the Detection of Endolymphatic Hydrops

Ito, Muneharu; Watanabe, Yukio; Shojaku, Hideo; Kobayashi, Hideto; Aso, Shin; Mizukoshi, Kanemasa

doi:10.3109/00016489309128123

Cited by 19 publications

(12 citation statements)

References 8 publications

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“…Unfortunately, the electronystagmography test is most abnormal during an attack and although abnormal eye movements can be created in laboratory animals, they are unpredictable in a clinical setting. Ito et al 17 found that vestibular ocular reflexes were accurate predictors of disease in 50% of their patients with classic Meniere's disease. More recently, Dobie et al 18 showed that when there are audiologic signs and symptoms of Meniere's disease, the electronystagmography test is normal in 25% of the cases.…”

Section: Introductionmentioning

confidence: 99%

Use of electrocochleography in the diagnosis of meniere's disease

1998

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Section: Introductionmentioning

confidence: 99%

Use of electrocochleography in the diagnosis of meniere's disease

1998

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“…Schuknecht called this condition delayed endolymphatic hydrops (DEH) and subdivided this disease into 3 types: ipsilateral, contralateral and bilateral [1,2]. Several clinical tests (caloric test, furosemide test, glycerol test and electrocochleography) are applied to evaluate patients with DEH [3,4]. However, these tests are not suitable for evaluating the otolith organs.…”

Section: Introductionmentioning

confidence: 99%

Vestibular Evoked Myogenic Potentials in Ipsilateral Delayed Endolymphatic Hydrops

Ohki

Matsuzaki²,

Sugasawa³

et al. 2002

ORL

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We recorded vestibular evoked myogenic potentials (VEMPs) in 12 patients diagnosed as having ipsilateral delayed endolymphatic hydrops (DEH). Seventy-five percent (9/12) of the patients showed decreased or absent VEMPs in the affected ears. Almost all patients had normal VEMPs in the unaffected ears. In addition, in 4 patients, VEMPs were recorded before and 3 h after oral glycerol administration (1.3 g/kg body weight). VEMPs improved after glycerol administration in 2 of the 3 patients whose VEMPs had been abnormal in the affected ears before glycerol administration. None of the 4 patients presented significant changes in VEMPs in the unaffected ears after glycerol administration. Improvement of VEMPs after glycerol administration confirmed the existence of endolymphatic hydrops in patients with ipsilateral DEH. In conclusion, VEMPs are useful to evaluate the function of otolith organs in patients with ipsilateral DEH, and the glycerol test using VEMPs may be useful to detect endolymphatic hydrops in ipsilateral DEH.

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“…Ito et al recently reported that with a test battery of ECoG and the furosemide test, abnormal responses were found in 51/58 (88%) patients with definite MD in each of the tests [7]. Kimura et al reported that 97% of 118 patients with definite MD showed at least one positive test result in a battery of three tests, and that the combination of three rather than two tests resulted in an improved diagnostic accuracy [6].…”

Section: Discussionmentioning

confidence: 99%

Comparison of the diagnostic value of 3 T MRI after intratympanic injection of GBCA, electrocochleography, and the glycerol test in patients with Meniere's disease

Fukuoka¹,

Takumi²,

Tsukada³

et al. 2011

Acta Oto-Laryngologica

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Conclusion.3 T MRI after intratympanic injection of gadolinium-based contrast agent (GBCA) is more useful for the diagnosis of endolymphatic hydrops compared with the glycerol test and electrocochleography (ECoG).Objective:To investigate the relationship between 3 T MRI after intratympanic injection of GBCA, the glycerol test, and ECoG in patients with Meniere's disease (MD).Methods:A total of 20 patients with MD were evaluated. Diluted gadodiamide (a gadolinium-based contrast agent) was administered to the bilateral tympanic cavity by injection through the tympanic membrane. After 24 h, the endolymphatic hydrops was evaluated by a 3.0 T MR scanner. To investigate cochlear hydrops, the glycerol test and ECoG were carried out in all patients.Results:A positive result was observed in 11 patients (55%) in the glycerol test and in 12 patients (60%) by ECoG. The incidence of positive findings when evaluating the same patients with both the glycerol test and ECoG increased to 75%. Nineteen of 20 (95%) patients showed positive results for 3 T MRI.

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Furosemide vor Test for the Detection of Endolymphatic Hydrops

Cited by 19 publications

References 8 publications

Use of electrocochleography in the diagnosis of meniere's disease

Use of electrocochleography in the diagnosis of meniere's disease

Vestibular Evoked Myogenic Potentials in Ipsilateral Delayed Endolymphatic Hydrops

Comparison of the diagnostic value of 3 T MRI after intratympanic injection of GBCA, electrocochleography, and the glycerol test in patients with Meniere's disease

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