2007
DOI: 10.1016/j.toxlet.2007.05.286
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Further development of an in vitro skin absorption method to measure compartmental disposition and kinetics for chemicals in skin

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“…A new experimental approach based on ex vivo human skin has recently been investigated, whereby parameters, such as skin compartmental concentrations and delivery kinetics (flux) of chemicals, can be measured (31). In addition, ongoing work funded by COLIPA aims to derive similar predictions of skin compartment-specific bioavailability through the in silico, mathematical modelling of chemistry parameter data sets (13).…”
Section: ) Consumer Exposure Informationmentioning
confidence: 99%
“…A new experimental approach based on ex vivo human skin has recently been investigated, whereby parameters, such as skin compartmental concentrations and delivery kinetics (flux) of chemicals, can be measured (31). In addition, ongoing work funded by COLIPA aims to derive similar predictions of skin compartment-specific bioavailability through the in silico, mathematical modelling of chemistry parameter data sets (13).…”
Section: ) Consumer Exposure Informationmentioning
confidence: 99%