Further Observations on a Human Syncytial Virus From a Nasopharyngeal Carcinoma2

Epstein, M. A.; Achong, B. G.; Ball, G.

doi:10.1093/jnci/53.3.681

Cited by 30 publications

(25 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Ten different serotypes of simian foamy virus (SFV) have been isolated from tissues of healthy or diseased New World and Old World monkeys (Hooks & Gibbs, 1975;Hooks & Hooks, 1981 ;Rhodes-Feuillette et al, 1979). An isolate obtained from human nasopharyngeal carcinoma tissue has been shown to be related to the SFV types 6 and 7 previously found in chimpanzees (Achong et al, 1971 ;Epstein et al, 1974;Brown et al, 1978).…”

Section: Introductionmentioning

confidence: 72%

Purification and Characterization of the Major Envelope Glycoprotein of Simian Foamy Virus Type 1

Benzair

Rhodes-Feuillette

Lasneret

et al. 1985

Journal of General Virology

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 72%

Purification and Characterization of the Major Envelope Glycoprotein of Simian Foamy Virus Type 1

Benzair

Rhodes-Feuillette

Lasneret

et al. 1985

Journal of General Virology

View full text Add to dashboard Cite

“…After 3 h of adsorption at 37 °C with intermittent shaking, 70 ml of fresh medium were added. When a good cytopathic effect (Epstein et aL 1974) involving more than 80 % of the cells was observed, the infected cultures, both cells and medium, were harvested and stored at -70 °C in small volumes.…”

Section: Methodsmentioning

confidence: 99%

Preliminary Seroepidemiological Studies on the Human Syncytial Virus

Achong

Epstein

1978

Journal of General Virology

Self Cite

View full text Add to dashboard Cite

SUMMARYThe seroepidemiology of the human syncytial virus was investigated by means of an indirect immunofluorescence test on 24I sera from Kenya, Tunisia, Singapore and Britain. These included sera from patients with nasopharyngeal carcinoma, other tumours of the oro-nasopharynx, tumours of other parts of the body, and from normal donors. In this study, the virus was found to infect only Kenyan Africans and all but one of these seropositive subjects had tumours, particularly of the oro-nasopharyngeal spaces. The significance of these findings is discussed.

show abstract

“…This isolate was termed human FV because of its origin and became the prototypic laboratory strain when it was subsequently sequenced and infectious molecular clones were derived (68,85,86). Shortly after the isolation of SFVcpz(hu), the original authors concluded that SFVcpz(hu) was a distinct type of FV most closely related to Simian FV (SFV) types 6 and 7, both isolated from chimpanzees (28). In a contradictory report, Brown et al concluded that SFVcpz(hu) was not a distinct type of FV but rather a variant strain of chimpanzee FV (20).…”

Section: Origin Of "Human" Fvmentioning

confidence: 99%

Historical Perspective of Foamy Virus Epidemiology and Infection

2001

View full text Add to dashboard Cite

Foamy viruses (FV) are complex retroviruses which are widespread in many species. Despite being discovered over 40 years ago, FV are among the least well characterized retroviruses. The replication of these viruses is different in many interesting respects from that of all other retroviruses. Infection of natural hosts by FV leads to a lifelong persistent infection, without any evidence of pathology. A large number of studies have looked at the prevalence of primate foamy viruses in the human population. Many of these studies have suggested that FV infections are prevalent in some human populations and are associated with specific diseases. More recent data, using more rigorous criteria for the presence of viruses, have not confirmed these studies. Thus, while FV are ubiquitous in all nonhuman primates, they are only acquired as rare zoonotic infections in humans. In this communication, we briefly discuss the current status of FV research and review the history of FV epidemiology, as well as the lack of pathogenicity in natural, experimental, and zoonotic infections

show abstract

Further Observations on a Human Syncytial Virus From a Nasopharyngeal Carcinoma2

Cited by 30 publications

References 0 publications

Purification and Characterization of the Major Envelope Glycoprotein of Simian Foamy Virus Type 1

Purification and Characterization of the Major Envelope Glycoprotein of Simian Foamy Virus Type 1

Preliminary Seroepidemiological Studies on the Human Syncytial Virus

Historical Perspective of Foamy Virus Epidemiology and Infection

Contact Info

Product

Resources

About