GABAA overactivation potentiates the effects of NMDA blockade during the brain growth spurt in eliciting locomotor hyperactivity in juvenile mice

Regional Dysregulation and Aberrant Functional Connectivity in ADHD

“…(iii) N-methyl-D-aspartate (NMDA) neonatally-injected antagonist models in rodents, e.g. NMDA blockade during the brain growth spurt period (Oliveira-Pinto et al, 2015) [66], and single unit recordings of basal and glutamateinduced excitability of pyramidal neurons in the prefrontal cortex of anaesthetised rats coupled with microiontophoresis (Di Miceli and Gronier, 2016) [67], as well as biomorphic electrode concurrent evaluations of glutamate in aligned networks of the frontal cortex that involve the cingulate, prelimbic, infralimbic and dorsal peduncle regions (Miller et al, 2015. [68] (iv) Models based upon changes induced by the environment, e.g.…”