GAMBARAN KADAR ASAM URAT PADA MAHASISWA ANGKATAN 2011 FAKULTAS KEDOKTERAN UNIVERSITAS  SAM RATULANGI DENGAN INDEKS MASSA TUBUH ≥ 23 kg/m2

Karimba, Andre; Kaligis, Stefana H.M.; Purwanto, Diana S.

doi:10.35790/ebm.1.1.2013.1175

Cited by 5 publications

(5 citation statements)

References 9 publications

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“…This may be due to genetic factors that contribute to elevated uric acid levels and reduced physical activity (Rau, Ongkowijaya, & Kawengian, 2015). Another study found their high levels of uric acid in the respondents overweight and obesity with the possible result of a decrease in renal excretion of uric acid due to insulin resistance and hyperinsulinemia occurring in the state of overweight and obesity (Karimba, Kaligis, and Purwanto, 2013).…”

Section: Resultsmentioning

confidence: 99%

Macronutrient Intake, Vitamin C, Purine Intake, Body Mass Index and Uric Acid Levels in Man (Aged 26-45 Years Old) in Rw 05 Sub-District Bukit Duri Jakarta

Wahyuni

Kholifah

Jus’at

2020

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Hyperurisemia is a condition that uric acid levels in blood above the normal value. Uric acid levels are influenced by consumption of purines, carbohydrate intake, protein, fat, vitamin C and Body Mass Indeks (BMI). The purpose of study was to describe correlation of consumption of purine, carbohydrate intake, protein, fat, vitamin C, BMI and uric acid level in man (aged 26-45 years old) in RW 05 sub-district Bukit Duri Jakarta, 2017. This study was used a cross sectional design with sample of 56 man aged 26-45 years old. Data of carbohydrate , protein, fat,vitamin C and purine intake were collected from Food Frequency Questionaire semi quantitative used food phothograph. BMI was measured by is a person’s weight in kilograms divided by the square of height in meters. Uric acid levels was measured by GCU Easy Touch. Data was analyzed by Pearson’s test and One-Way ANOVA test. There are 56 respondents, as many as 57.1% had normal uric acid levels. While 37.5% respondents have high uric acid levels. Based on statistical Pearson’s test showed there are significant relation between consumption of purine (0,001), protein intake (0,001), fat intake (0,001), vitamin C (0,008) and uric acid levels. There is not relation between carbohidrat intake (0,259), IMT (0,117). Another One-Way ANOVA test founded that there are differences consumption of purine, carbohydrate intake, protein, fat, vitamin C based on uric acid levels (p<0,020). The higher intake of the purin, protein and fat increases uric acid levels. The higher intake of the vitamin C can reduce uric acid levels

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Section: Resultsmentioning

confidence: 99%

Macronutrient Intake, Vitamin C, Purine Intake, Body Mass Index and Uric Acid Levels in Man (Aged 26-45 Years Old) in Rw 05 Sub-District Bukit Duri Jakarta

Wahyuni

Kholifah

Jus’at

2020

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“…Sehingga pada keadaan hiperinsulinemia pada pra diabetes terjadi peningkatan reabsorbsi yang akan menyebabkan hiperurisemia. 8,9 Konsumsi makanan sehari-hari dapat mempengaruhi kadar asam urat. Mengonsumsi makanan-makanan seafood dan daging sangat berpengaruh terjadinya gout.…”

Section: Uji Statistikunclassified

“…Sehingga pada keadaan hiperinsulinemia pada pra diabetes terjadi peningkatan reabsorbsi yang akan menyebabkan hiperurisemia. 8,9 Obesitas dapat didefinisikan sebagai kelebihan lemak tubuh. Penanda kandungan lemak tubuh yang digunakan adalah indeks masa tubuh (IMT), yang dapat dihitung sebagai Berat badan (kg)/Tinggi badan (m 2 ).…”

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Perbandingan Kadar Asam Urat Pada Subyek Obes Dan Non-Obes Di Fakultas Kedokteran Universitas Sam Ratulangi Manado

Rau¹,

Ongkowijaya²,

Kawengian³

2015

eCl

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Uric acid is the end product of purine metabolism. Circulating uric acid in the human body is produced by the body (endogenous uric acid) as well as derived from food (exogenous uric acid). Normal serum uric acid level is <7.0 mg / dL in men and <6.0 in women. Obesity can be defined as excess body fat. One of the markers used for body fat content is body mass index (BMI). This study aimed to compare the levels of uric acid in obese and non-obese subjects. This was an analytical study with a cross sectional design. The population is students of Faculty of Medicine University of Sam Ratulangi Manado. Samples were male students of batch 2013. There were 42 male students, consisted of 21 obese and 21 non-obese students. The results showed that the average of uric acid levels in obese group was 8.05 mg/dL and in non-obese group 6.63 mg/dL. In the obese group, 67% had an increase in uric acid level meanwhile in the non-obese group only 38%. The statistical test showed a sig 0,009. Conclusion: In this study, the average of uric acid level in obese group was significantly higher than in the non-obese group. However, there were students with either normal or high uric acid levels in both groups.Keywords: uric acid, obeseAbstrak: Asam urat merupakan produk akhir metabolisme purin. Asam urat yang beredar di dalam tubuh manusia di produksi sendiri oleh tubuh (asam urat endogen) dan berasal dari makanan (asam urat eksogen). Normalnya kadar asam urat serum <7,0 mg/dL pada pria dan <6,0 mg/dL pada wanita. Obesitas dapat di definisikan sebagai kelebihan lemak tubuh. Penanda kandungan lemak tubuh yang digunakan ialah indeks masa tubuh (IMT). Penelitian ini bertujuan untuk mengetahui perbandingan kadar asam urat pada subyek obes dan non obes. Penelitian ini bersifat analitik dengan pendekatan potong lintang. Populasi penelitian ialah mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi Manado. Sampel idalah mahasiswa pria angkatan 2013 dan didapatkan 42 orang yang terbagi atas 21 obes dan 21 non obes. Hasil penelitian memperlihatkan rerata kadar asam urat pada obes 8,05 mg/dL dan pada non-obes 6,63 mg/dL. Peningkatan kadar asam urat ditemukan 67% pada kelompok obes dan 38% pada kelompok non-obes. Uji statistik menunjukkan nilai sig 0,009. Simpulan: Pada penelitian ini rerata kadar asam urat pada kelompok obes lebih tinggi secara bermakna daripada kelompok non-obes. Walaupun demikian, pada kedua kelompok ditemukan mahasiswa dengan kadar asam urat normal maupun meningkat.Kata kunci: asam urat, obesitas

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“…4 Untuk prevalensi hiperurisemia di daerah Minahasa Sulawesi Utara berdasarkan penelitian yang dilakukan oleh Rotty yang memiliki prevalensi 34,30% pada laki-laki dan 23,31% pada perempuan. 5 Peningkatan kadar asam urat dalam darah (hiperurisemia) disebabkan oleh dua keadaan yang mengganggu keseimbangan kadar purin dalam tubuh manusia, yaitu peningkatan produksi purin dan penurunan ekskresi asam urat. Peningkatan produksi purin dapat disebabkan oleh karena konsumsi makanan tinggi purin sedangkan penurunan eksresi asam urat dapat terjadi akibat gangguan fungsi ginjal.…”

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Gambaran kadar asam urat darah pada pekerja kantor

Darmawan¹,

Kaligis²,

Assa³

2016

eBM

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Prolonged hyperuricemia is the cause of gout arthritis, which has become one of burden diseases in the wide society. Several conditions can increase hyperuricemia and one of that conditions is insulin resistance associated with decreased physical activity. People with low physical activity like office workers have a higher risk of hyperuricemia. This study was aimed to describe the level of blood uric acid among office workers. This was a descriptive study with a cross-sectional design using total sampling method to obtain respondents. The results showed that there were 52 respondents in this study. Thirty eight respondents (79,1%) had normal blood uric acid level and 14 respondents (26,9%) had high blood uric acid level. The average of blood uric acid level was 6,09 mg/dL,the median was 6.15 mg/dL, the minimum and maximum values were 3 mg/dL and 9,36 mg/dL respectively, and the standard of deviation was 1,615 mg/dL. Of 14 respondents with high blood uric acid level, one was female (7.1%) and the rest were males (92.9%). Conclusion: The majority of office workers had normal blood uric acid.Keywords: blood uric acid, office workers. Abstrak: Hiperurisemia yang berkepanjangan merupakan penyebab terjadinya penyakit gout arthritis, yang telah menjadi salah satu beban penyakit dimasyarakat. Beberapa keadaan dapat meningkatkan kejadian hiperurisemia, salah satunya ialah resistensi insulin yang terkait dengan penurunan aktivitas fisik. Orang dengan aktivitas fisik yang rendah seperti pekerja kantor berisiko tinggi terhadap terjadinya hiperurisemia. Penelitian ini bertujuan untuk mengetahui gambaran kadar asam urat pada pekerja kantor. Jenis penelitian ialah deskriptif dengan metode total sampling. Hasil penelitian mendapatkan 52 pekerja kantor sebagai responden. Terdapat 38 orang (79,1%) memiliki kadar asam urat dalam batas normal dan 14 orang (26,9%) memiliki kadar asam urat tinggi. Nilai rerata kadar asam urat darah 6,09 mg/dL, nilai median 6,15 mg/Dl, nilai minimum dan maksimum pada 3 mg/dL dan 9mg/dL serta standar deviasi 1,615 mg/dL. Dari 14 responden tersebut terdapat satu orang perempuan (7,1%) sedangkan sisanya ialah laki-laki (92,9%) . Simpulan: Sebagian besar pekerja kantor memiliki kadar asam urat darah normal. Kata kunci: asam urat darah, pekerja kantor.

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GAMBARAN KADAR ASAM URAT PADA MAHASISWA ANGKATAN 2011 FAKULTAS KEDOKTERAN UNIVERSITAS SAM RATULANGI DENGAN INDEKS MASSA TUBUH ≥ 23 kg/m2

Cited by 5 publications

References 9 publications

Macronutrient Intake, Vitamin C, Purine Intake, Body Mass Index and Uric Acid Levels in Man (Aged 26-45 Years Old) in Rw 05 Sub-District Bukit Duri Jakarta

Macronutrient Intake, Vitamin C, Purine Intake, Body Mass Index and Uric Acid Levels in Man (Aged 26-45 Years Old) in Rw 05 Sub-District Bukit Duri Jakarta

Perbandingan Kadar Asam Urat Pada Subyek Obes Dan Non-Obes Di Fakultas Kedokteran Universitas Sam Ratulangi Manado

Gambaran kadar asam urat darah pada pekerja kantor

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