Gambaran Kejadian Efek Samping Pada Penggunaan Obat Off Label Pasien Lupus

Yuwindry, Iwan; Noval,

doi:10.51817/bjp.v4i1.273

Cited by 2 publications

(3 citation statements)

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“…The occurrence of side effects in the use of Off Label drugs occurs due to the nature and potential of drugs to cause side effects such as drug selection, the period of drug use and the interaction between drugs. Each drug has a different mechanism and place of action so that it can cause different side effects [10].…”

Section: Incidence Of Off-label Side Effectsmentioning

confidence: 99%

Study of the Impact of Side Effects of Using Off-Label Drugs in Patients with Systemic Lupus Erythematosus on Health Costs

Yuwindry¹,

Yusri²,

Tangkas³

2023

Journal of Advances in Medicine and Pharmaceutical Sciences (JA

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The main problem in conducting lupus treatment is that most drugs for the therapy provided have not been authorized so that they are still included in the class of off-label drugs for the treatment of lupus. The use of off-label drugs can carry the potential for side effects in Lupus patients which have an impact on increasing health costs. This study aims to determine the impact of side effects of using off-label drugs on health costs in lupus patients, as an integrated evaluation in seeking to improve the quality of life and ensure proper care in Lupus patients. This study was conducted using a cross-sectional method by means of a survey using the Naranjo Algorithm instrument (PESO Book) to determine the incidence rate of side effects that exist in LSE therapy using off-label drugs and calculate the health costs of lupus patients. The results showed that the most respondents were in adulthood (19 respondents or 47.5%), then the most respondents were female (37 respondents or 92.5%). Data on the incidence of side effects obtained the most respondents in the Probable category (most likely to occur ROM) of 14 respondents or 35%. In addition, data on health costs incurred by more respondents experienced an increase, namely 23 respondents or 57.5%. The research data shows the calculated r value is 0.3044 and the Sig (2-tailed) value is 0.000 with a confidence level (CI) of 0.05. The results of the analysis clearly show that there is a significant relationship between the side effects of using off-label drugs on the health costs of lupus patients, in this correlation there is a unidirectional relationship, where if the value of side effects experienced by respondents is high, the value of respondents' health costs is also high.

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Section: Incidence Of Off-label Side Effectsmentioning

confidence: 99%

Study of the Impact of Side Effects of Using Off-Label Drugs in Patients with Systemic Lupus Erythematosus on Health Costs

Yuwindry¹,

Yusri²,

Tangkas³

2023

Journal of Advances in Medicine and Pharmaceutical Sciences (JA

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“…The immune system in Lupus patients will experience a loss of the ability to see the difference between foreign substances (non-self) and the body's cells and tissues. The World Health Organization or WHO records that the number of Lupus sufferers worldwide today has reached five million people (Yuwindry, I. (2020;Maria & Ediati, 2020).…”

Section: Introductionmentioning

confidence: 99%

“…Of the approximately 1,250,000 Indonesians affected by Lupus (assuming a prevalence of 0.5%), very few know they suffer from Lupus (Damayat & Wardani, 2023). Most of them are women of reproductive age, and every year more than 100 thousand new sufferers are found (Yuwindry, 2020).…”

Section: Introductionmentioning

confidence: 99%

Providing compensation for patients with diseases who cannot be given the COVID-19 Vaccine

Yamin,

Hidayat,

Sadino

2023

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This study aims to describe the procedures and barriers associated with compensating disease sufferers who are not eligible to receive the COVID-19 vaccine. The research method used is normative research, which focuses on analyzing legal aspects based on legal regulations, including Presidential Regulation Number 99 of 2020, concerning Procurement of Vaccines and Implementation of Vaccinations in the Context of Overcoming the 2019 Coronavirus Disease (COVID-19) Pandemic, as well as regulations other relevant matters. Research data was obtained through literature study and document analysis, including primary and secondary legal materials. Data analysis was carried out descriptively and qualitatively with a deductive approach, which refers to general legal principles. The research results identified various obstacles, including technical problems such as a lack of public discipline in undergoing health checks before receiving vaccination and a lack of compliance from medical personnel who manage vaccination procedures per established guidelines. As a result, some groups of people who should not receive the COVID-19 vaccine still receive vaccination, which can ultimately cause side effects. The research also highlights Presidential Regulation Number 14 of 2021 concerning Procurement of Vaccines and Implementation of Vaccinations in the Context of Overcoming the COVID-19 Pandemic, which provides compensation guarantees following applicable regulations if a Post-Vaccination Adverse Event (AEFI) occurs which has the potential to cause disability or death in sufferers of the disease who are not eligible to receive the COVID-19 vaccine. The results of this research provide a deeper understanding of the challenges and obstacles in implementing COVID-19 vaccination, especially in the context of disease sufferers who do not meet the requirements to receive the vaccine, as well as the importance of guaranteeing compensation in AEFI situations that have the potential to have profound impacts.

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Gambaran Kejadian Efek Samping Pada Penggunaan Obat Off Label Pasien Lupus

Cited by 2 publications

References 0 publications

Study of the Impact of Side Effects of Using Off-Label Drugs in Patients with Systemic Lupus Erythematosus on Health Costs

Study of the Impact of Side Effects of Using Off-Label Drugs in Patients with Systemic Lupus Erythematosus on Health Costs

Providing compensation for patients with diseases who cannot be given the COVID-19 Vaccine

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