Gamma Responses Correlate with Temporal Expectation in Monkey Primary Visual Cortex

Lima, Bruss; Singer, Wolf; Neuenschwander, Sergio

doi:10.1523/jneurosci.0957-11.2011

Cited by 91 publications

(91 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…First, elevated narrowband gamma power was a major factor predicting stimulus detection, similar to the role of gamma in visual detection in primates (Fries, 2015;Lima et al, 2011;Womelsdorf et al, 2006). Second, pre-stimulus decorrelation-most prominent in FS neuronspreceded successful stimulus detection, as in primates (Cohen and Maunsell, 2009;Mitchell et al, 2009).…”

Section: Discussionmentioning

confidence: 73%

Cortical states control visual spatial perception

Speed

Rosario

Burgess

et al. 2018

Preprint

View full text Add to dashboard Cite

SummaryMany factors modulate the state of cortical activity, but the importance of cortical states for sensory perception remains debated.We trained mice to detect spatially localized visual stimuli, and simultaneously measured local field potentials and excitatory and inhibitory neuron populations across layers of primary visual cortex (V1). Cortical states with low firing rates and correlations between excitatory neurons, and reduced oscillatory activity in Layer 4, accurately predicted single trials of visual spatial detection behavior. Our results show that cortical states exert strong effects at the initial stage of cortical processing in V1, and play a decisive role for visual spatial behavior in mice.

show abstract

Section: Discussionmentioning

confidence: 73%

Cortical states control visual spatial perception

Speed

Rosario

Burgess

et al. 2018

Preprint

View full text Add to dashboard Cite

show abstract

“…These results have been supported by studies in humans showing enhancement of the early visual P1 potential in response to targets with high temporal expectation (Doherty, Rao, Mesulam, & Nobre, 2005;Zanto et al, 2011). Additionally, studies in humans and nonhuman primates have shown that temporal expectation modulates anticipatory neural activity to enhance the perceptual processing of events occurring at expected times (Besle et al, 2011;Cravo, Rohenkohl, Wyart, & Nobre, 2013;Green & McDonald, 2010;Lima et al, 2011;Praamstra, Kourtis, Kwok, & Oostenveld, 2006;Praamstra & Pope, 2007;Stefanics et al, 2010;van Ede, de Lange, Jensen, & Maris, 2011).…”

Section: Introductionmentioning

confidence: 66%

“…Electrophysiological studies in nonhuman primates have shown that visual areas such as V1 (Lakatos, Karmos, Mehta, Ulbert, & Schroeder, 2008;Lima, Singer, & Neuenschwander, 2011;Shuler & Bear, 2006), V4 (Ghose & Maunsell, 2002), MT (Ghose & Bearl, 2010), and IT (Anderson & Sheinberg, 2008) are Citation: Rohenkohl, G., Gould, I. C., Pessoa, J., & Nobre, A. C. (2014). Combining spatial and temporal expectations to improve visual perception.…”

Section: Introductionmentioning

confidence: 99%

Combining spatial and temporal expectations to improve visual perception

et al. 2014

View full text Add to dashboard Cite

The importance of temporal expectations in modulating perceptual functions is increasingly recognized. However, the means through which temporal expectations can bias perceptual information processing remains ill understood. Recent theories propose that modulatory effects of temporal expectations rely on the co-existence of other biases based on receptive-field properties, such as spatial location. We tested whether perceptual benefits of temporal expectations in a perceptually demanding psychophysical task depended on the presence of spatial expectations. Foveally presented symbolic arrow cues indicated simultaneously where (location) and when (time) target events were more likely to occur. The direction of the arrow indicated target location (80% validity), while its color (pink or blue) indicated the interval (80% validity) for target appearance. Our results confirmed a strong synergistic interaction between temporal and spatial expectations in enhancing visual discrimination. Temporal expectation significantly boosted the effectiveness of spatial expectation in sharpening perception. However, benefits for temporal expectation disappeared when targets occurred at unattended locations. Our findings suggest that anticipated receptive-field properties of targets provide a natural template upon which temporal expectations can operate in order to help prioritize goal-relevant events from early perceptual stages.

show abstract

“…Much attention has been focused on gamma LFP activity in cortical areas and their possible function, for example in coordinating activation between distant cortical areas (72)(73)(74). At the same time, it has been noted that gamma oscillations in sensory cortices tend to be poorly coupled to aspects of visual stimuli or decision-related task variables, calling into question whether they are sufficiently reliable indicators of cortical processing (75).…”

Section: Discussionmentioning

confidence: 99%

Basal forebrain contributes to default mode network regulation

Nair

Klaassen

Arató³

et al. 2018

Proc. Natl. Acad. Sci. U.S.A.

View full text Add to dashboard Cite

The default mode network (DMN) is a collection of cortical brain regions that is active during states of rest or quiet wakefulness in humans and other mammalian species. A pertinent characteristic of the DMN is a suppression of local field potential gamma activity during cognitive task performance as well as during engagement with external sensory stimuli. Conversely, gamma activity is elevated in the DMN during rest. Here, we document that the rat basal forebrain (BF) exhibits the same pattern of responses, namely pronounced gamma oscillations during quiet wakefulness in the home cage and suppression of this activity during active exploration of an unfamiliar environment. We show that gamma oscillations are localized to the BF and that gamma-band activity in the BF has a directional influence on a hub of the rat DMN, the anterior cingulate cortex, during DMNdominated brain states. The BF is well known as an ascending, activating, neuromodulatory system involved in wake-sleep regulation, memory formation, and regulation of sensory information processing. Our findings suggest a hitherto undocumented role of the BF as a subcortical node of the DMN, which we speculate may be important for switching between internally and externally directed brain states. We discuss potential BF projection circuits that could underlie its role in DMN regulation and highlight that certain BF nuclei may provide potential target regions for up-or down-regulation of DMN activity that might prove useful for treatment of DMN dysfunction in conditions such as epilepsy or major depressive disorder.gamma suppression | anterior cingulate cortex | granger causality A highly consistent finding across a wide range of functional imaging studies in humans is that a network of brain regions, referred to as the "default mode network" (DMN), increases its activity during passive mental states compared with the performance of cognitive tasks. This was initially shown in a metaanalysis of several PET studies (1), in which a distribution of brain regions broadly including the medial prefrontal, retrosplenial, and anterior cingulate cortex (ACC), as well as lateral parietal and temporal cortices, was shown to be activated when subjects were in a state of quiet restfulness. The DMN areas are thought to form a cohesive set of intrinsically coupled brain regions, such that fMRI activations in its component regions exhibit similar time courses, allowing them to be identified reliably using seed-region analysis (2-4). Activity in the DMN exhibits anticorrelation with a complementary, largely nonoverlapping, set of fronto-parietal brain areas known as the "dorsal attention network" (DAN) (5). It should be noted, however, that particular brain structures may harbor functionally heterogeneous elements and thus may contribute to multiple functions, as was shown for the ACC (6). During wakefulness, the human brain thus alternates between DAN-and DMN-dominated activation states, corresponding to effortful cognitive task performance on the one hand and quiet restful...

show abstract

Gamma Responses Correlate with Temporal Expectation in Monkey Primary Visual Cortex

Cited by 91 publications

References 59 publications

Cortical states control visual spatial perception

Cortical states control visual spatial perception

Combining spatial and temporal expectations to improve visual perception

Basal forebrain contributes to default mode network regulation

Contact Info

Product

Resources

About