Gastroenteritis: A Continuing Problem of Child Health in Britain

Tripp, J.; Wilmers, MaryJ.; Wharton, B. A.

doi:10.1016/s0140-6736(77)92846-x

Cited by 37 publications

(7 citation statements)

References 6 publications

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“…Relatively few of the patients in our series were seriously dehydrated and ill. Of all of the 357 admitted with diarrhoea in the 12-month period, only 5 (1.4%) required IV infusion therapy and this was mostly necessitated by complicating disorders rather than severe dehydration. This fits with the current trend in the UK (13,14).…”

Section: Discussionsupporting

confidence: 90%

Safety and Efficacy of Three Oral Rehydration Solutions for Children with Diarrhoea (Edinburgh 1984–85)

et al. 1989

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Of 357 children with acute diarrhoea admitted to the City Hospital, Edinburgh, over a 12-month period, only 5 (1.4%) required IV infusions. Three hundred and nineteen were treated with oral rehydration (OR). Of these 269 were studied in detail and 43% had signs of dehydration, but in none of them was it severe. There were no fatalities. Patients were randomly allocated to treatment with one of three OR solutions in a double blind trial. The solutions had sodium concentrations of 35, 50 and 90 mmol (mEq)/l, and dextrose of 200 (36 g/l), 111 (20 g/l) and 110 (19.8 g/l) mmol/l, respectively. Hypernatraemia was not a clinical problem and only 5 children (2%) were biochemically hypernatraemic on admission. Treatment did not cause clinical hypernatraemia. At the second assessment only 3 children were biochemically hypernatraemic, one from each treatment group, and no one had clinical signs. All three solutions were safe and effective in the relatively mildly dehydrated patients currently seen in the UK.

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Section: Discussionsupporting

confidence: 90%

Safety and Efficacy of Three Oral Rehydration Solutions for Children with Diarrhoea (Edinburgh 1984–85)

et al. 1989

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“…Recent surveys from Hackney (London) and Newcastle upon Tyne show a decline in the duration and severity of infantile gastroenteritis (British Medical Journal, 1977b;Pullan et al, 1977;Tripp et al, 1977) but severe dehydration and prolonged diarrhoea were still common in the very young babies. In the present study only 10% of the children were under 3 months, and from the younger babies other viruses or no pathogens were found in the stools more often than rotavirus.…”

Section: Discussionmentioning

confidence: 99%

A year's experience of the rotavirus syndrome and its association with respiratory illness.

Lewis¹,

Parry²,

Davies³

et al. 1979

Archives of Disease in Childhood

101

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SUMMARY In a hospital study rotavirus was identified in 51 % of 152 children with diarrhoea. These patients showed a clinical pattern that was distinct from patients in whom the diarrhoea was associated with bacteria, other viruses, or no pathogens. A respiratory illness was described in 66 % of rotavirus patients and usually preceded the gastrointestinal symptoms. Vomiting lasted between one and 3 days and was curtailed by substituting the normal diet with clear fluids. Watery diarrhoea continued for 4 or 5 days, even when rehydration was by the intravenous rather than the oral route. Prolonged diarrhoea was rare. Most children infected with rotavirus were under 2 years of age, but dehydration was most severe in infants aged between 12 and 18 months. A clinician can thus recognise the rotavirus syndrome and expect spontaneous recovery if adequate rehydration is maintained for a critical few days.

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“…As in earlier reports of nonbacterial gastroenteritis where viral studies were not done (Gribbin et al, 1975;Tripp et al, 1977), most studies of rotavirus gastroenteritis report that boys are more often affected than girls (see Table 1). The reason for this male predominance is not yet clear, but it is most obvious in the younger children.…”

Section: Sex Ratiomentioning

confidence: 64%

Rotavirus gastroenteritis.

Walker-Smith¹

1978

Archives of Disease in Childhood

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Gastroenteritis: A Continuing Problem of Child Health in Britain

Cited by 37 publications

References 6 publications

Safety and Efficacy of Three Oral Rehydration Solutions for Children with Diarrhoea (Edinburgh 1984–85)

Safety and Efficacy of Three Oral Rehydration Solutions for Children with Diarrhoea (Edinburgh 1984–85)

A year's experience of the rotavirus syndrome and its association with respiratory illness.

Rotavirus gastroenteritis.

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