Gastrointestinal issues in cystic fibrosis: a lifetime of disease

Abstract

Cystic fibrosis (CF) is one of the most common inherited diseases in the UK, affecting 1:2500 live births. There are now more adults than children with CF in the UK, with a median survival of approximately 40 years. The pulmonary complications of CF are commonly understood and are the main cause of mortality; however, gastrointestinal (GI) complications are wide ranging and remain a primary cause of morbidity. Common GI complications include malabsorption and pancreatic insufficiency; however, less well known are problems such as inflammatory bowel disease and GI cancers. Managing lung disease has historically been the principal aim of care; however, with an increasingly older population GI complications must be addressed; the CF community urgently needs to engage with gastroenterologists who are willing to develop a special interest in this area.

Model for predicting of the liver cirrhosis development in children with cystic fibrosis

“…Читайте нас на сайте: http://med expert.com.ua rity, does not develop in all patients with this pathology [12]. The variety of clinical manifesta tions of hepatobiliary system lesions in patients with CF are represented by increased liver enzymes, newborn cholestasis, liver steatosis, focal biliary cirrhosis, multilobular cirrhosis, pathology of the gall bladder [4,14].…”