GC-MS analysis of ethyl acetate extract of &lt;i&gt;Ficus sycomorus&lt;/i&gt; root Linn. (Moraceae

Abubakar, U.; Danmalam, U.H.; Ahmed, Amran; Abdullahi, S.M.; Abba, A.; Rukayya, N.

doi:10.4314/bajopas.v9i2.6

Cited by 5 publications

(7 citation statements)

References 3 publications

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“…Steroids is absent in both extracts. This agreed with previous findings [36][37][38][39]. In another study using root back extract of the same plant, reducing sugar was also found [40].…”

Section: Phytochemical Constituents Of F Sycomorus Stem Bark Extractssupporting

confidence: 92%

Potential of Silver Nano Particles Synthesized from Ficus sycomorus Linn Against Multidrug Resistant Shigella species Isolated from Clinical Specimens

Saheed¹,

Umar²,

Iliyasu³

2020

AJLS

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Ficus sycomorus Plant was known traditionally for its medicinal properties, Shigella species as a bacterial was also known for their resistance to orthodox medicine. Hence the synthesis of silver nanoparticles from Ficus sycomorus. This study was carried out to investigate the anti-shigellosis potential of silver nanoparticles synthesized from Ficus sycomorus Linn stem bark aqueous extract against Multi-drug Resistant (MDR) Shigella species isolated from clinical specimen collected from patients attending Yobe State Specialist Hospital Damaturu, Nigeria. A total of 400 diarrhoeagenic stools were screened for isolation of Shigella species and determined their antibiotic susceptibility pattern using standard methods. Phytochemical constituents of Ficus sycomorus extract were used to synthesize silver nanoparticles using green synthesis approach. The nanoparticles was analyzed for transmittance, functional groups, sizes and shapes using Uv-vis, FTIR and Scanning Electron Microscopy (SEM), and was tested for antibacterial activities on MDR Shigella isolates. There is no significant difference in Shigella recovery relation to patients gender (P<0.05). The age group, 0-10 years were more susceptible, 40% (36), followed by >30 years (21). Shigella were also found to be sensitive to Ciprofloxacin (92%), Augmentin (87%), Cefuroxime (85%), Streptomycin (83.5%) while the most frequent resistance was showcased against Nalidixic Acid (48%), and Tetracycline (27%). Phytochemicals detected include saponins, flavonoids, alkaloids, cardiac glycoside and tannin. Uv-vis showed broad peaks around 460nm, the FTIR showed C-H stretch of hydroxyl group of alkanes and the SEM showed nanoparticles with wide range of shapes and sizes. Anti-Shigella activities of silver nanoparticles is higher at zones of inhibition between 10mm and 30mm higher compared to the activities of crude aqueous extract and AgNO 3 solution against the MDR Shigella species which showed an enhanced activities. The high prevalence of shigellosis among children in this study, indicated that improved hygiene is needed for children in the area and detailed examination is required for the treatment of diarrhoea in adults. Ciprofloxacin and Amoxicillin Clavulanate, Nalidixic acid could be used only where culture and sensitivity results prevailed. Enhanced traditional medicine should be given priority because of its potentials. This study have demonstrated feasibility of the green synthesis of F. sycomorus as a potent antishigellosis to combat the global burden of the disease. This is the first study On Stem bark aqueous extracts of F. sycomorus against shigella species in the area.

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“…Steroids is absent in both extracts. This agreed with previous findings [36][37][38][39]. In another study using root back extract of the same plant, reducing sugar was also found [40].…”

Section: Phytochemical Constituents Of F Sycomorus Stem Bark Extractssupporting

confidence: 92%

Potential of Silver Nano Particles Synthesized from Ficus sycomorus Linn Against Multidrug Resistant Shigella species Isolated from Clinical Specimens

Saheed¹,

Umar²,

Iliyasu³

2020

AJLS

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“…This analysis was performed to study the effects of gamma rays on secondary compounds of (Ficus palmata) the best doses of gamma 30 &40 Gray, as they increased the secondary compounds of the plant. These results were confirmed by (Abubakar et al, 2016) 15-methyltricyclo[6.5.2(13,14).0(7,15)]pentadeca-1,3,5,7,9,11,13-heptene 25.79 C16H14 206 23.30 Acetic acid,10,7,7, [6.5.2(13,14).0(7,15)]pentadeca-1, 3,5,7,9,11,13- (5,6,7,8-tetrahydro-2,8,8-trimethyl-4h-cyclohepta[b]furan-5-yl)-…”

Section: Effect Of Radiation On Secondary Compounds In Callus Of Ficu...supporting

confidence: 65%

“…The mass spectrometric detector was operated in an electron impact ionization mode with an ionizing energy of 70 eV. (Abubakar et al, 2016).…”

Section: Gc-ms Analysismentioning

confidence: 99%

Molecular Genetic Studies on (Ficus Palmata & Ficus Carica Subsp Rupestris.) Under the Effect of Gamma Radiation by Tissue Culture Techniques

Eissa

Sayed

Allah

et al. 2021

Al-Azhar Journal of Agricultural Research

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Ficus spp. are used as medicine and are used to reducing the risk of cancer and heart disease. The phytochemical screening of the Ficus palmata plant extracts showed the presence of alkaloids, tannins, flavonoids, terpenoids and cardiac glycosides. This investigation was undertaken by using tissue culture technique on Ficus palmata & Ficus carica subsp rupestris. Study the effect of gamma rays doses of 0.0, 20, 30 and 40 Gy on callus production and the secondary plant constituents. The highest callus fresh weightand callus induction were achieved by callus derived from (leaves & stem) explants, which were cultured on (MS) medium supplemented with different concentrations of 2,4-D at 2.0 (mg/l) and Kin at 0.2 (mg/l). Polymerase chain reaction (PCR) amplification using eight ISSR primers showed polymorphic patterns with different response to gamma radiation doses. found genetic differences at the molecular level using ISSR with gamma doses compared to control. The total number of polymorphic bands was 239 bands (99.58% polymorphism). Found that there was genetic stability between the mother plants and product tissue culture for plants (Ficus palmata & Ficus carica subsp rupestris). The chemical composition of Ficus palmata was studied by means of GC-MS analysis under the effect of gamma radiation. The best doses of gamma were 30 & 40 Gy, as they increased the secondary compounds of Ficus palmata.

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“…Abubakar et al, [40] reported that, the leaves of Fiscus sycomorus have antidiabetic, antioxidant, antitumor, and antibacterial activity. Also the aqueous extract of stem bark exhibits sedative, anticonvulsant and muscular activities due to the present of alkaloids, flavonoids and other phytoconstituents.…”

Section: Pharmacological Activities Of Nigerian Medicinal Plantsmentioning

confidence: 99%

Phytochemical Compositions in Some Nigerian Medicinal Plants and Their Pharmacological Properties: A Review

Kutama¹,

Abdulkadir²,

Kwalli³

et al. 2018

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Nigeria is naturally blessed with both savannah and tropical rainforests vegetation and these offer a wide distribution of plants believed to possesses secondary metabolites which are responsible for treating or curing various diseases. Several researches have been carried out in order to explore and identify the chemical compositions responsible for various pharmacological activities in Nigerian medicinal plants. This paper discussed the meaning and historical development of medicinal plants. A brief account of phytochemicals (alkaloids and flavonoids) were also given. The plants presented in this paper confirmed the pharmacological activities of these plants and includes;

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GC-MS analysis of ethyl acetate extract of <i>Ficus sycomorus</i> root Linn. (Moraceae

Cited by 5 publications

References 3 publications

Potential of Silver Nano Particles Synthesized from <i>Ficus sycomorus</i> <i>Linn</i> Against Multidrug Resistant <i>Shigella species</i> Isolated from Clinical Specimens

Potential of Silver Nano Particles Synthesized from <i>Ficus sycomorus</i> <i>Linn</i> Against Multidrug Resistant <i>Shigella species</i> Isolated from Clinical Specimens

Molecular Genetic Studies on (Ficus Palmata & Ficus Carica Subsp Rupestris.) Under the Effect of Gamma Radiation by Tissue Culture Techniques

Phytochemical Compositions in Some Nigerian Medicinal Plants and Their Pharmacological Properties: A Review

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GC-MS analysis of ethyl acetate extract of <i>Ficus sycomorus</i> root Linn. (Moraceae

Cited by 5 publications

References 3 publications

Potential of Silver Nano Particles Synthesized from &lt;i&gt;Ficus sycomorus&lt;/i&gt; &lt;i&gt;Linn&lt;/i&gt; Against Multidrug Resistant &lt;i&gt;Shigella species&lt;/i&gt; Isolated from Clinical Specimens

Potential of Silver Nano Particles Synthesized from &lt;i&gt;Ficus sycomorus&lt;/i&gt; &lt;i&gt;Linn&lt;/i&gt; Against Multidrug Resistant &lt;i&gt;Shigella species&lt;/i&gt; Isolated from Clinical Specimens

Molecular Genetic Studies on (Ficus Palmata & Ficus Carica Subsp Rupestris.) Under the Effect of Gamma Radiation by Tissue Culture Techniques

Phytochemical Compositions in Some Nigerian Medicinal Plants and Their Pharmacological Properties: A Review

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Potential of Silver Nano Particles Synthesized from <i>Ficus sycomorus</i> <i>Linn</i> Against Multidrug Resistant <i>Shigella species</i> Isolated from Clinical Specimens

Potential of Silver Nano Particles Synthesized from <i>Ficus sycomorus</i> <i>Linn</i> Against Multidrug Resistant <i>Shigella species</i> Isolated from Clinical Specimens