The first purpose of this study is to test the validity and reliability of the Self-Silencing Scale in a Turkish sample. The second purpose of this study is to examine if there is any relationships between selfsilencing and general distress, and to investigate if there is any mediating role of self-esteem on this possible relationship. A total of 427 university students within the range age of 18 to 31 years, with a mean age of 20.70 participated in this study. Participants were administered The Self-Silencing Scale, Two-Dimensional Self-Esteem Scale, Depression, Anxiety, and Stress Scale (DASS), and a personal information form. CFA and regression-based mediation analyzes were carried out in the study. According to the CFA result, the 29-item structure of the scale was confirmed in the Turkish sample. As another result of the research, the findings revealed a negative significant relationship between selfsilencing and self-esteem. On the other hand, a positive significant relationship was found between selfsilencing and depression, anxiety and stress. In addition, self-esteem mediated the relationship between self-silencing and depression, anxiety and stress. The indirect effects of self-silencing on general distress were also found to be significant. In other words, it has been observed that self-silencing has both direct effects on depression, anxiety and stress, and indirect effects through self-esteem.