Gender difference in the association of dietary patterns and metabolic parameters with obesity in young and middle-aged adults with dyslipidemia and abnormal fasting plasma glucose in Taiwan

Abstract

BackgroundThe increasing prevalence of obesity has become a pandemic problem, and dietary patterns are one of the important factors causing obesity. Although the correlation between dietary patterns and obesity has been well explored, the gender difference on the association between dietary patterns and obesity remains unclear. The objective of this study examined whether gender difference existed in the relationship of dietary patterns with metabolic parameters and specific indices of adiposity among young and middle-aged adults with dyslipidemia and abnormal fasting plasma glucose (FPG) in Taiwan.MethodsA total of 14,087 subjects aged between 20 and 50 years with dyslipidemia and abnormal FPG were recruited in Taiwan between 2001 and 2010 for a cross-sectional study. Dyslipidemia was defined primarily according to the National Cholesterol Education Program Adult Treatment Panel III guidelines with minor modification. Abnormal FPG level was defined by the American Diabetes Association. Principal component analysis was conducted to identify dietary patterns. Multivariate logistic regression analysis was performed to evaluate the association of dietary patterns and metabolic parameters with different indices of adiposity including general obesity, central obesity, and high body fat, stratified by gender.ResultsTwo dietary patterns derived from principal component analysis were the prudent dietary pattern and the western dietary pattern. Both men and women in the highest quartile of the western dietary pattern had a significantly increased odds ratio of general obesity, central obesity, and high body fat. However, only male subjects in the higher quartiles of the prudent dietary pattern had a significantly decreased odds ratio of all indices of obesity. Both men and women with higher high-density lipoprotein cholesterol and total cholesterol levels had a significantly reduced odds ratio of general and central obesity, while those with higher triglycerides and FPG levels had a significantly increased odds ratio of general and central obesity. Higher low-density lipoprotein cholesterol level was significantly associated with an elevated odds ratio of high body fat, while higher total cholesterol level was significantly correlated with a reduced odds ratio of high body fat only in women.ConclusionsGender difference exists in the association of dietary patterns and metabolic parameters with obesity and body fat in young and middle-aged adults with dyslipidemia and abnormal FPG in Taiwan.

Obesity and Dyslipidemia in Chinese Adults: A Cross-Sectional Study in Shanghai, China

“…Compared with females, significantly higher risk of different forms of dyslipidemia was observed in obese males. A possible reason for this is the intensity of work pressure, unhealthy lifestyle and diets for males, which account for excessive fat accumulation [ 44 ]. The proportion of smoking and drinking among males is higher than that of females, which are risk factors of dyslipidemia [ 45 ].…”

Modified WCRF/AICR Score and All-Cause, Digestive System, Cardiovascular, Cancer and Other-Cause-Related Mortality: A Competing Risk Analysis of Two Cohort Studies Conducted in Southern Italy

“…Our study showed that for DSD-related mortality and for cancer-related mortality, only in the male sub-cohort did an association emerge between a high score and a reduction in mortality risk. As well as for other-cause mortality in the female sub-cohort, gender differences have been reported also for dietary habits, as well as individual responses to dietary intake [71,72]. Indeed, there appears to be some resistance to following a healthy diet in males [73].…”

Lipid Profile dan Tekanan Darah pada Wanita Dewasa Berdasarkan Pemeriksaan BMI dan LP

“…Namun tidak adanya hubungan antara BMI dengan total kolesterol dan trigliserida dalam penelitian ini bertentangan dengan hasil penelitian yang menyatakan bahwa obesitas berhubungan dengan profil lipid darah (Eslami et al, 2019;Lin et al, 2019). Trigliserida berhubungan dengan BMI dan lemak tubuh, dan total kolesterol berhubungan positif dengan lingkar pinggang, namun memiliki hubungan negatif dengan lemak tubuh (Telles et al, 2018).…”