Abstract. Let S ⊆ {0, +, −, + 0 , − 0 , * , #} be a set of symbols, where + (resp., −, + 0 and − 0 ) denotes a positive (resp., negative, nonnegative and nonpositive) real number, and * (resp., #) denotes a nonzero (resp., arbitrary) real number. An S-pattern is a matrix with entries in S. In particular, a {0, +, −}-pattern is a sign pattern and a {0, * }-pattern is a zero-nonzero pattern. This paper extends the following problems concerning spectral properties of sign patterns and zero-nonzero patterns to S-patterns: spectrally arbitrary patterns; inertially arbitrary patterns; refined inertially arbitrary patterns; potentially nilpotent patterns; potentially stable patterns; and potentially purely imaginary patterns. Relationships between these classes of S-patterns are given and techniques that appear in the literature are extended. Some interesting examples and properties of patterns when # belongs to the symbol set are highlighted. For example, it is shown that there is a {0, +, #}-pattern of order n that is spectrally arbitrary with exactly 2n − 1 nonzero entries. Finally, a modified version of the nilpotent-Jacobian method is presented that can be used to show a pattern is inertially arbitrary.